(Q36772397)

16 August 2017

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title

Natural products of filamentous fungi: enzymes, genes, and their regulation (English)

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16 August 2017

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Dirk Hoffmeister

1

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16 August 2017

Nancy P Keller

series ordinal

2

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16 August 2017

publication date

20 December 2006

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16 August 2017

published in

Natural Product Reports

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16 August 2017

volume

24

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16 August 2017

issue

2

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16 August 2017

page(s)

393-416

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Pigments of fungi (Macromycetes).

16 August 2017

cites work

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Biologically active compounds from Aphyllophorales (polypore) fungi

21 January 2018

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21 January 2018

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Molecular biology of mycotoxin biosynthesis

21 January 2018

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Host-selective toxins: agents of compatibility

21 January 2018

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Natural products--a simple model to explain chemical diversity

21 January 2018

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Metabolic pathway gene clusters in filamentous fungi

21 January 2018

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LaeA, a regulator of secondary metabolism in Aspergillus spp

21 January 2018

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Role of Horizontal Gene Transfer in the Evolution of Fungi.

21 January 2018

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Horizontal gene transfer and the evolution of secondary metabolite gene clusters in fungi: an hypothesis

21 January 2018

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The biosynthesis, molecular genetics and enzymology of the polyketide-derived metabolites

21 January 2018

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Advances in cloning, functional analysis and heterologous expression of fungal polyketide synthase genes

21 January 2018

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Phylogenomic analysis of type I polyketide synthase genes in pathogenic and saprobic ascomycetes.

21 January 2018

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Twenty-five coregulated transcripts define a sterigmatocystin gene cluster in Aspergillus nidulans

21 January 2018

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Genetic organization and function of the aflatoxin B1 biosynthetic genes

21 January 2018

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Enzyme reactions and genes in aflatoxin biosynthesis

21 January 2018

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Dothistroma pini, a forest pathogen, contains homologs of aflatoxin biosynthetic pathway genes

21 January 2018

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A polyketide synthase gene required for biosynthesis of the aflatoxin-like toxin, dothistromin.

21 January 2018

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A polyketide synthase gene required for ochratoxin A biosynthesis in Aspergillus ochraceus

21 January 2018

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Development of a Real Time PCR system for detection of Penicillium nordicum and for monitoring ochratoxin A production in foods by targeting the ochratoxin polyketide synthase gene.

21 January 2018

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The developmentally regulated Aspergillus nidulans wA gene encodes a polypeptide homologous to polyketide and fatty acid synthases

21 January 2018

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Gene cluster involved in melanin biosynthesis of the filamentous fungus Alternaria alternata

21 January 2018

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Structural analysis of PKS1, a polyketide synthase gene involved in melanin biosynthesis in Colletotrichum lagenarium

21 January 2018

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A melanin polyketide synthase (PKS) gene from Nodulisporium sp. that shows homology to the pks1 gene of Colletotrichum lagenarium

21 January 2018

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Biosynthesis of fungal melanins and their importance for human pathogenic fungi

21 January 2018

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Identification of a polyketide synthase gene (pksP) of Aspergillus fumigatus involved in conidial pigment biosynthesis and virulence.

21 January 2018

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Hydrolytic polyketide shortening by ayg1p, a novel enzyme involved in fungal melanin biosynthesis

21 January 2018

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Molecular cloning and characterization of WdPKS1, a gene involved in dihydroxynaphthalene melanin biosynthesis and virulence in Wangiella (Exophiala) dermatitidis

21 January 2018

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Putative polyketide synthase and laccase genes for biosynthesis of aurofusarin in Gibberella zeae

21 January 2018

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GIP2, a putative transcription factor that regulates the aurofusarin biosynthetic gene cluster in Gibberella zeae

21 January 2018

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Identification of a gene cluster responsible for the biosynthesis of aurofusarin in the Fusarium graminearum species complex

21 January 2018

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The polyketide synthase gene pks4 from Gibberella fujikuroi encodes a key enzyme in the biosynthesis of the red pigment bikaverin.

21 January 2018

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Two different polyketide synthase genes are required for synthesis of zearalenone in Gibberella zeae

21 January 2018

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Characterization of two polyketide synthase genes involved in zearalenone biosynthesis in Gibberella zeae

21 January 2018

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The PKS4 gene of Fusarium graminearum is essential for zearalenone production

21 January 2018

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Novel polyketide synthase from Nectria haematococca

21 January 2018

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Polyketide synthase gene responsible for citrinin biosynthesis in Monascus purpureus

21 January 2018

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Molecular cloning and characterization of an ML-236B (compactin) biosynthetic gene cluster in Penicillium citrinum

21 January 2018

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A polyketide synthase is required for fungal virulence and production of the polyketide T-toxin

21 January 2018

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A polyketide synthase gene required for biosynthesis of fumonisin mycotoxins in Gibberella fujikuroi mating population A.

21 January 2018

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Characterization of four clustered and coregulated genes associated with fumonisin biosynthesis in Fusarium verticillioides

21 January 2018

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Co-expression of 15 contiguous genes delineates a fumonisin biosynthetic gene cluster in Gibberella moniliformis.

21 January 2018

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Fumonisin production in the maize pathogen Fusarium verticillioides: genetic basis of naturally occurring chemical variation

21 January 2018

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A bidomain nonribosomal peptide synthetase encoded by FUM14 catalyzes the formation of tricarballylic esters in the biosynthesis of fumonisins

21 January 2018

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Functional replacement of the ketosynthase domain of FUM1 for the biosynthesis of fumonisins, a group of fungal reduced polyketides.

21 January 2018

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Regulation of fumonisin B(1) biosynthesis and conidiation in Fusarium verticillioides by a cyclin-like (C-type) gene, FCC1.

21 January 2018

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An iterative type I polyketide synthase PKSN catalyzes synthesis of the decaketide alternapyrone with regio-specific octa-methylation

21 January 2018

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Functional analysis of the polyketide synthase genes in the filamentous fungus Gibberella zeae (anamorph Fusarium graminearum).

21 January 2018

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Fusarin C biosynthesis in Fusarium moniliforme and Fusarium venenatum.

21 January 2018

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Equisetin biosynthesis in Fusarium heterosporum

21 January 2018

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6-Methylsalicylic acid synthetase from Penicillium patulum. Some catalytic properties of the enzyme and its relation to fatty acid synthetase

21 January 2018

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The multifunctional 6-methylsalicylic acid synthase gene of Penicillium patulum. Its gene structure relative to that of other polyketide synthases

21 January 2018

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Purification and properties of 6-methylsalicylic acid synthase from Penicillium patulum

21 January 2018

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Cloning of the polyketide synthase gene atX from Aspergillus terreus and its identification as the 6-methylsalicylic acid synthase gene by heterologous expression

21 January 2018

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Cloning and molecular characterization of Penicillium expansum genes upregulated under conditions permissive for patulin biosynthesis.

21 January 2018

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Endogenous lipogenic regulators of spore balance in Aspergillus nidulans

21 January 2018

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Oxylipins act as determinants of natural product biosynthesis and seed colonization in Aspergillus nidulans

21 January 2018

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Three putative oxylipin biosynthetic genes integrate sexual and asexual development in Aspergillus nidulans

21 January 2018

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Aspergillus cyclooxygenase-like enzymes are associated with prostaglandin production and virulence.

21 January 2018

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Modular Peptide Synthetases Involved in Nonribosomal Peptide Synthesis

21 January 2018

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Biosynthesis of natural products on modular peptide synthetases

21 January 2018

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Nonribosomal peptides: from genes to products

21 January 2018

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Biosynthesis of nonribosomal peptides1.

21 January 2018

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Penicillin and cephalosporin biosynthetic genes: structure, organization, regulation, and evolution

21 January 2018

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Evolution of beta-lactam biosynthesis genes and recruitment of trans-acting factors

21 January 2018

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The reaction cycle of isopenicillin N synthase observed by X-ray diffraction

21 January 2018

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Structure of a cephalosporin synthase

21 January 2018

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Amplification and disruption of the phenylacetyl-CoA ligase gene of Penicillium chrysogenum encoding an aryl-capping enzyme that supplies phenylacetic acid to the isopenicillin N-acyltransferase

21 January 2018

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Biosynthesis of cyclosporin A: partial purification and properties of a multifunctional enzyme from Tolypocladium inflatum

21 January 2018

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The peptide synthetase catalyzing cyclosporine production in Tolypocladium niveum is encoded by a giant 45.8-kilobase open reading frame

21 January 2018

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Structure and localization of cyclosporin synthetase, the key enzyme of cyclosporin biosynthesis in Tolypocladium inflatum

21 January 2018

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delta-(L-alpha-Aminoadipyl)-L-cysteinyl-D-valine synthetase, that mediates the first committed step in penicillin biosynthesis, is a cytosolic enzyme.

21 January 2018

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Biotechnology and genetics of ergot alkaloids

21 January 2018

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d-lysergic acid-activating enzyme from the ergot fungus Claviceps purpurea

21 January 2018

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The Claviceps purpurea gene encoding dimethylallyltryptophan synthase, the committed step for ergot alkaloid biosynthesis.

21 January 2018

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Evidence for an ergot alkaloid gene cluster in Claviceps purpurea

21 January 2018

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Molecular cloning and analysis of the ergopeptine assembly system in the ergot fungus Claviceps purpurea

21 January 2018

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The ergot alkaloid gene cluster in Claviceps purpurea: extension of the cluster sequence and intra species evolution

21 January 2018

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Origins and significance of ergot alkaloid diversity in fungi

21 January 2018

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Identification of the cytochrome P450 monooxygenase that bridges the clavine and ergoline alkaloid pathways

21 January 2018

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Elimination of ergovaline from a grass-Neotyphodium endophyte symbiosis by genetic modification of the endophyte

21 January 2018

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The determinant step in ergot alkaloid biosynthesis by an endophyte of perennial ryegrass

21 January 2018

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Elimination of ergoline alkaloids following treatment of Ipomoea asarifolia (Convolvulaceae) with fungicides

21 January 2018

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Molecular characterization of a seed transmitted clavicipitaceous fungus occurring on dicotyledoneous plants (Convolvulaceae)

21 January 2018

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An ergot alkaloid biosynthesis gene and clustered hypothetical genes from Aspergillus fumigatus

21 January 2018

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Overproduction, purification and characterization of FgaPT2, a dimethylallyltryptophan synthase from Aspergillus fumigatus

21 January 2018

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Reverse prenyltransferase in the biosynthesis of fumigaclavine C in Aspergillus fumigatus: gene expression, purification, and characterization of fumigaclavine C synthase FGAPT1.

21 January 2018

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The epipolythiodioxopiperazine (ETP) class of fungal toxins: distribution, mode of action, functions and biosynthesis

21 January 2018

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The sirodesmin biosynthetic gene cluster of the plant pathogenic fungus Leptosphaeria maculans

21 January 2018

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The ABC transporter gene in the sirodesmin biosynthetic gene cluster of Leptosphaeria maculans is not essential for sirodesmin production but facilitates self-protection

21 January 2018

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Bioinformatic and expression analysis of the putative gliotoxin biosynthetic gene cluster of Aspergillus fumigatus

21 January 2018

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Disruption of a nonribosomal peptide synthetase in Aspergillus fumigatus eliminates gliotoxin production

21 January 2018

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GliZ, a transcriptional regulator of gliotoxin biosynthesis, contributes to Aspergillus fumigatus virulence

21 January 2018

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Overproduction, purification and characterization of FtmPT1, a brevianamide F prenyltransferase from Aspergillus fumigatus

21 January 2018

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The fumitremorgin gene cluster of Aspergillus fumigatus: identification of a gene encoding brevianamide F synthetase

21 January 2018

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Molecular genetics of fungal siderophore biosynthesis and uptake: the role of siderophores in iron uptake and storage

21 January 2018

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Characterization of the Ustilago maydis sid2 gene, encoding a multidomain peptide synthetase in the ferrichrome biosynthetic gene cluster

21 January 2018

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The distal GATA sequences of the sid1 promoter of Ustilago maydis mediate iron repression of siderophore production and interact directly with Urbs1, a GATA family transcription factor

21 January 2018

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The siderophore system is essential for viability of Aspergillus nidulans: functional analysis of two genes encoding l-ornithine N 5-monooxygenase (sidA) and a non-ribosomal peptide synthetase (sidC).

21 January 2018

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Nonribosomal peptide synthesis in Schizosaccharomyces pombe and the architectures of ferrichrome-type siderophore synthetases in fungi

21 January 2018

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Analysis of a nonribosomal peptide synthetase gene from Alternaria brassicae and flanking genomic sequences.

21 January 2018

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A cyclic peptide synthetase gene required for pathogenicity of the fungus Cochliobolus carbonum on maize

21 January 2018

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A putative branched-chain-amino-acid transaminase gene required for HC-toxin biosynthesis and pathogenicity in Cochliobolus carbonum

21 January 2018

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A eukaryotic alanine racemase gene involved in cyclic peptide biosynthesis

21 January 2018

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Identification of peptide synthetase-encoding genes from filamentous fungi producing host-selective phytotoxins or analogs

21 January 2018

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The destruxins: synthesis, biosynthesis, biotransformation, and biological activity

21 January 2018

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Molecular characterization of the enniatin synthetase gene encoding a multifunctional enzyme catalysing N-methyldepsipeptide formation in Fusarium scirpi

21 January 2018

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Bacterial expression of catalytically active fragments of the multifunctional enzyme enniatin synthetase.

21 January 2018

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Enniatin synthetase is a monomer with extended structure: evidence for an intramolecular reaction mechanism

21 January 2018

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Identification of peptaibols from Trichoderma virens and cloning of a peptaibol synthetase.

21 January 2018

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Multiple non-ribosomal peptide synthetase genes determine peptaibol synthesis in Trichoderma virens

21 January 2018

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A symbiosis expressed non-ribosomal peptide synthetase from a mutualistic fungal endophyte of perennial ryegrass confers protection to the symbiotum from insect herbivory

21 January 2018

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Expressed sequence tags and genes associated with loline alkaloid expression by the fungal endophyte Neotyphodium uncinatum.

21 January 2018

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Gene clusters for insecticidal loline alkaloids in the grass-endophytic fungus Neotyphodium uncinatum

21 January 2018

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Gibberellin biosynthesis in Gibberella fujikuroi: cloning and characterization of the copalyl diphosphate synthase gene

21 January 2018

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Gibberellin biosynthetic pathway in Gibberella fujikuroi: evidence for a gene cluster

21 January 2018

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The P450-1 gene of Gibberella fujikuroi encodes a multifunctional enzyme in gibberellin biosynthesis

21 January 2018

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The gibberellin 20-oxidase of Gibberella fujikuroi is a multifunctional monooxygenase

21 January 2018

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Characterization of the final two genes of the gibberellin biosynthesis gene cluster of Gibberella fujikuroi: des and P450-3 encode GA4 desaturase and the 13-hydroxylase, respectively

21 January 2018

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AREA directly mediates nitrogen regulation of gibberellin biosynthesis in Gibberella fujikuroi, but its activity is not affected by NMR.

21 January 2018

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Biosynthesis of gibberellins in Gibberella fujikuroi: biomolecular aspects

21 January 2018

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Gibberellin biosynthesis in fungi: genes, enzymes, evolution, and impact on biotechnology

21 January 2018

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Functional characterization of two cytochrome P450 monooxygenase genes, P450-1 and P450-4, of the gibberellic acid gene cluster in Fusarium proliferatum (Gibberella fujikuroi MP-D).

21 January 2018

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Distribution of gibberellin biosynthetic genes and gibberellin production in the Gibberella fujikuroi species complex

21 January 2018

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Molecular cloning and genetic analysis of an indole-diterpene gene cluster from Penicillium paxilli

21 January 2018

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Four gene products are required for the fungal synthesis of the indole-diterpene, paspaline

21 January 2018

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Indole-diterpene gene cluster from Aspergillus flavus

21 January 2018

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Molecular cloning and genetic analysis of a symbiosis-expressed gene cluster for lolitrem biosynthesis from a mutualistic endophyte of perennial ryegrass

21 January 2018

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A complex gene cluster for indole-diterpene biosynthesis in the grass endophyte Neotyphodium lolii

21 January 2018

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Cyclophilin A and calcineurin functions investigated by gene inactivation, cyclosporin A inhibition and cDNA arrays approaches in the phytopathogenic fungus Botrytis cinerea

21 January 2018

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Evidence for a gene cluster involving trichothecene-pathway biosynthetic genes in Fusarium sporotrichioides

21 January 2018

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The Tri4 gene of Fusarium sporotrichioides encodes a cytochrome P450 monooxygenase involved in trichothecene biosynthesis

21 January 2018

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Tri13 and Tri7 determine deoxynivalenol- and nivalenol-producing chemotypes of Gibberella zeae

21 January 2018

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Inactivation of a cytochrome P-450 is a determinant of trichothecene diversity in Fusarium species

21 January 2018

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Trichothecene 3-O-acetyltransferase protects both the producing organism and transformed yeast from related mycotoxins. Cloning and characterization of Tri101.

21 January 2018

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The mystery of the trichothecene 3-O-acetyltransferase gene. Analysis of the region around Tri101 and characterization of its homologue from Fusarium sporotrichioides

21 January 2018

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Tri16 Is Required for Esterification of Position C-8 during Trichothecene Mycotoxin Production by Fusarium sporotrichioides

21 January 2018

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Characterization of a fusarium 2-gene cluster involved in trichothecene C-8 modification

21 January 2018

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The trichothecene biosynthesis gene cluster of Fusarium graminearum F15 contains a limited number of essential pathway genes and expressed non-essential genes

21 January 2018

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Multiplex PCR assay for the identification of nivalenol, 3- and 15-acetyl-deoxynivalenol chemotypes in Fusarium.

21 January 2018

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Functional demarcation of the Fusarium core trichothecene gene cluster

21 January 2018

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Cloning of a gene cluster responsible for the biosynthesis of diterpene aphidicolin, a specific inhibitor of DNA polymerase alpha.

21 January 2018

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A carotenoid biosynthesis gene cluster in Fusarium fujikuroi: the genes carB and carRA.

21 January 2018

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Mutants of the carotene cyclase domain of al-2 from Neurospora crassa

21 January 2018

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Characterization of a gene in the car cluster of Fusarium fujikuroi that codes for a protein of the carotenoid oxygenase family

21 January 2018

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Cloning of the astaxanthin synthase gene from Xanthophyllomyces dendrorhous (Phaffia rhodozyma) and its assignment as a beta-carotene 3-hydroxylase/4-ketolase

21 January 2018

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Structural diversity and functional novelty of new carotenoid biosynthesis genes

21 January 2018

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Regulation of secondary metabolism in filamentous fungi

21 January 2018

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Relationship between secondary metabolism and fungal development

21 January 2018

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Signalling pathways connecting mycotoxin production and sporulation

21 January 2018

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Fungal secondary metabolism - from biochemistry to genomics

21 January 2018

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Sequence-specific binding by Aspergillus nidulans AflR, a C6 zinc cluster protein regulating mycotoxin biosynthesis

21 January 2018

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Secondary metabolic gene cluster silencing in Aspergillus nidulans.

21 January 2018

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Clustered pathway genes in aflatoxin biosynthesis

21 January 2018

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Functional analysis of mlcR, a regulatory gene for ML-236B (compactin) biosynthesis in Penicillium citrinum

21 January 2018

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Regulation of cyclic peptide biosynthesis in a plant pathogenic fungus by a novel transcription factor

21 January 2018

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AcFKH1, a novel member of the forkhead family, associates with the RFX transcription factor CPCR1 in the cephalosporin C-producing fungus Acremonium chrysogenum

21 January 2018

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Winged helix transcription factor CPCR1 is involved in regulation of beta-lactam biosynthesis in the fungus Acremonium chrysogenum

21 January 2018

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The penicillin regulator PENR1 of Aspergillus nidulans is a HAP-like transcriptional complex

21 January 2018

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HAP-Like CCAAT-binding complexes in filamentous fungi: implications for biotechnology.

21 January 2018

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The aflatoxin pathway regulator AflR induces gene transcription inside and outside of the aflatoxin biosynthetic cluster

21 January 2018

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A novel regulatory gene, Tri10, controls trichothecene toxin production and gene expression

21 January 2018

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Cloning of the creA gene from Aspergillus nidulans: a gene involved in carbon catabolite repression

21 January 2018

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Studies on the role of the areA gene in the regulation of nitrogen catabolism in Aspergillus nidulans

21 January 2018

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Regulation of Aspergillus nidulans penicillin biosynthesis and penicillin biosynthesis genes acvA and ipnA by glucose

21 January 2018

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Ochratoxin A biosynthetic genes in Aspergillus ochraceus are differentially regulated by pH and nutritional stimuli

21 January 2018

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PAC1, a pH-regulatory gene from Fusarium verticillioides

21 January 2018

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Deletion of the Gibberella fujikuroi glutamine synthetase gene has significant impact on transcriptional control of primary and secondary metabolism

21 January 2018

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LaeA, a regulator of morphogenetic fungal virulence factors.

21 January 2018

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The expression of sterigmatocystin and penicillin genes in Aspergillus nidulans is controlled by veA, a gene required for sexual development

21 January 2018

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veA is required for toxin and sclerotial production in Aspergillus parasiticus

21 January 2018

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The lipid body protein, PpoA, coordinates sexual and asexual sporulation in Aspergillus nidulans

21 January 2018

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Deletion and allelic exchange of the Aspergillus fumigatus veA locus via a novel recyclable marker module.

21 January 2018

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Connection of propionyl-CoA metabolism to polyketide biosynthesis in Aspergillus nidulans.

21 January 2018

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Blockage of methylcitrate cycle inhibits polyketide production in Aspergillus nidulans

21 January 2018

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Signal transduction cascades regulating fungal development and virulence.

21 January 2018

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Aspergillus sporulation and mycotoxin production both require inactivation of the FadA G alpha protein-dependent signaling pathway

21 January 2018

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The Aspergillus nidulans sfaD gene encodes a G protein beta subunit that is required for normal growth and repression of sporulation

21 January 2018

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The phosducin-like protein PhnA is required for Gbetagamma-mediated signaling for vegetative growth, developmental control, and toxin biosynthesis in Aspergillus nidulans

21 January 2018

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The gprA and gprB genes encode putative G protein-coupled receptors required for self-fertilization in Aspergillus nidulans.

21 January 2018

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Regulation of aflatoxin synthesis by FadA/cAMP/protein kinase A signaling in Aspergillus parasiticus

21 January 2018

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G-protein signalling mediates differential production of toxic secondary metabolites

21 January 2018

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Distinct roles for two G protein alpha subunits in fungal virulence, morphology, and reproduction revealed by targeted gene disruption

21 January 2018

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The G protein alpha subunit Tga1 of Trichoderma atroviride is involved in chitinase formation and differential production of antifungal metabolites.

21 January 2018

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Lipid signaling in pathogenic fungi

21 January 2018

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Prostanoids and prostanoid receptors in signal transduction

21 January 2018

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The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids

21 January 2018

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Identification of 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids as ligands of the G protein-coupled receptor G2A

21 January 2018

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Functional analysis of all nonribosomal peptide synthetases in Cochliobolus heterostrophus reveals a factor, NPS6, involved in virulence and resistance to oxidative stress

21 January 2018

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Characterization of the function of the ver-1A and ver-1B genes, involved in aflatoxin biosynthesis in Aspergillus parasiticus

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1128/AEM.62.12.4568-4575.1996

Identifiers

DOI

10.1039/B603084J

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16 August 2017

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