(Q36435230)

14 August 2017

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title

The biosynthesis, molecular genetics and enzymology of the polyketide-derived metabolites (English)

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14 August 2017

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Alison M Hill

1

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14 August 2017

publication date

19 December 2005

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14 August 2017

published in

Natural Product Reports

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14 August 2017

volume

23

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14 August 2017

issue

2

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14 August 2017

page(s)

256-320

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Type I polyketide biosynthesis in bacteria (Part A--erythromycin biosynthesis).

14 August 2017

cites work

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Type I polyketide biosynthesis in bacteria (part B).

21 January 2018

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Biosynthesis of polyketides (other than actinomycete macrolides).

21 January 2018

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Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli

21 January 2018

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Biosynthesis of polyketides in heterologous hosts

21 January 2018

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Polyketide biosynthesis beyond the type I, II and III polyketide synthase paradigms

21 January 2018

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Nonribosomal peptides: from genes to products

21 January 2018

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Ways of assembling complex natural products on modular nonribosomal peptide synthetases

21 January 2018

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Multimodular biocatalysts for natural product assembly

21 January 2018

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Combinatorial biosynthesis of polyketides and nonribosomal peptides

21 January 2018

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Hybrid peptide-polyketide natural products: biosynthesis and prospects toward engineering novel molecules

21 January 2018

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Combinatorial biosynthesis of antibiotics: challenges and opportunities

21 January 2018

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4-[2-(2-amino-2-oxoethyl)-2,7-dihydroxy-4-oxochroman-5-yl]-3-hydroxybut-2-enoic acid

21 January 2018

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Building-block selectivity of polyketide synthases

21 January 2018

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Nonnatural substrates for polyketide synthases and their associated modifying enzymes

21 January 2018

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Genetic approaches to polyketide antibiotics. 1.

21 January 2018

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Antibiotic biosynthesis: from natural to unnatural compounds

21 January 2018

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Regulation and manipulation of the gene clusters encoding type-I PKSs

21 January 2018

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Combinatorial biosynthesis of antimicrobials and other natural products

21 January 2018

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21 January 2018

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Natural product biosynthesis: a new interface between enzymology and medicine

21 January 2018

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Modification of post-PKS tailoring steps through combinatorial biosynthesis

21 January 2018

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Enzymology of acyl chain macrocyclization in natural product biosynthesis

21 January 2018

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Intermodular communication in polyketide synthases: comparing the role of protein-protein interactions to those in other multidomain proteins

21 January 2018

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Engineering biodiversity with type II polyketide synthase genes

21 January 2018

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The chalcone synthase superfamily of type III polyketide synthases

21 January 2018

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Big effects from small changes: possible ways to explore nature's chemical diversity.

21 January 2018

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A biosynthetic classification of fungal and streptomycete fused-ring aromatic polyketides

21 January 2018

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Merging the potential of microbial genetics with biological and chemical diversity: an even brighter future for marine natural product drug discovery

21 January 2018

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Engineering of secondary metabolite pathways

21 January 2018

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Recent efforts in engineering microbial cells to produce new chemical compounds

21 January 2018

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Biochemical engineering of natural product biosynthesis pathways

21 January 2018

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Biogenetic speculation and biosynthetic advances

21 January 2018

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Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: Versatility from a unique substrate channel

21 January 2018

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Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases

21 January 2018

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Expression, site-directed mutagenesis, and steady state kinetic analysis of the terminal thioesterase domain of the methymycin/picromycin polyketide synthase

21 January 2018

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Loss of co-linearity by modular polyketide synthases: a mechanism for the evolution of chemical diversity

21 January 2018

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Skipping in a hybrid polyketide synthase. Evidence for ACP-to-ACP chain transfer

21 January 2018

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Chain initiation on the soraphen-producing modular polyketide synthase from Sorangium cellulosum

21 January 2018

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Metabolic engineering of a methylmalonyl-CoA mutase-epimerase pathway for complex polyketide biosynthesis in Escherichia coli

21 January 2018

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Enhancing the atom economy of polyketide biosynthetic processes through metabolic engineering.

21 January 2018

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A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity

21 January 2018

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Impact of thioesterase activity on tylosin biosynthesis in Streptomyces fradiae.

21 January 2018

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Role of type II thioesterases: evidence for removal of short acyl chains produced by aberrant decarboxylation of chain extender units

21 January 2018

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Process and metabolic strategies for improved production of Escherichia coli-derived 6-deoxyerythronolide B.

21 January 2018

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Stereochemistry of catalysis by the ketoreductase activity in the first extension module of the erythromycin polyketide synthase

21 January 2018

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Erythromycin biosynthesis. The 4-pro-S hydride of NADPH is utilized for ketoreduction by both module 5 and module 6 of the 6-deoxyerythronolide B synthase

21 January 2018

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Substrate specificity of the loading didomain of the erythromycin polyketide synthase

21 January 2018

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Engineering specificity of starter unit selection by the erythromycin-producing polyketide synthase

21 January 2018

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Alteration of the substrate specificity of the malonyl-CoA/acetyl-CoA:acyl carrier protein S-acyltransferase domain of the multifunctional fatty acid synthase by mutation of a single arginine residue

21 January 2018

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Precursor-directed biosynthesis of 16-membered macrolides by the erythromycin polyketide synthase.

21 January 2018

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Precursor-directed biosynthesis: biochemical basis of the remarkable selectivity of the erythromycin polyketide synthase toward unsaturated triketides

21 January 2018

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Assessing the balance between protein-protein interactions and enzyme-substrate interactions in the channeling of intermediates between polyketide synthase modules

21 January 2018

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Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations.

21 January 2018

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A defined system for hybrid macrolide biosynthesis in Saccharopolyspora erythraea

21 January 2018

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New erythromycin derivatives from Saccharopolyspora erythraea using sugar O-methyltransferases from the spinosyn biosynthetic gene cluster

21 January 2018

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Selective protein-protein interactions direct channeling of intermediates between polyketide synthase modules

21 January 2018

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Quantitative analysis of the relative contributions of donor acyl carrier proteins, acceptor ketosynthases, and linker regions to intermodular transfer of intermediates in hybrid polyketide synthases

21 January 2018

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Biosynthesis and combinatorial biosynthesis of pikromycin-related macrolides in Streptomyces venezuelae

21 January 2018

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Mechanisms of molecular recognition in the pikromycin polyketide synthase

21 January 2018

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The hidden steps of domain skipping: macrolactone ring size determination in the pikromycin modular polyketide synthase

21 January 2018

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Isolation and structure determination of novamethymycin, a new bioactive metabolite of the methymycin biosynthetic pathway in Streptomyces venezuelae

21 January 2018

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Characterization and analysis of the PikD regulatory factor in the pikromycin biosynthetic pathway of Streptomyces venezuelae

21 January 2018

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Biochemical evidence for an editing role of thioesterase II in the biosynthesis of the polyketide pikromycin

21 January 2018

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The Streptomyces venezuelae pikAV gene contains a transcription unit essential for expression of enzymes involved in glycosylation of narbonolide and 10-deoxymethynolide

21 January 2018

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Generation of multiple bioactive macrolides by hybrid modular polyketide synthases in Streptomyces venezuelae

21 January 2018

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An unexpected interaction between the modular polyketide synthases, erythromycin DEBS1 and pikromycin PikAIV, leads to efficient triketide lactone synthesis

21 January 2018

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The tylosin-biosynthetic genes of Streptomyces fradiae

21 January 2018

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Expression analysis of the tylosin-biosynthetic gene cluster: pivotal regulatory role of the tylQ product.

21 January 2018

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Differential roles of two SARP-encoding regulatory genes during tylosin biosynthesis.

21 January 2018

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Feedback control of polyketide metabolism during tylosin production

21 January 2018

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Influence of dimethylsulfoxide on tylosin production in Streptomyces fradiae

21 January 2018

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Genetic engineering of aminodeoxyhexose biosynthesis in Streptomyces fradiae

21 January 2018

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Functional analysis of OleY L-oleandrosyl 3-O-methyltransferase of the oleandomycin biosynthetic pathway in Streptomyces antibioticus

21 January 2018

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Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26.

21 January 2018

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Heterologous production of the antifungal polyketide antibiotic soraphen A of Sorangium cellulosum So ce26 in Streptomyces lividans

21 January 2018

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The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units

21 January 2018

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The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum

21 January 2018

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Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.

21 January 2018

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Myxobacteria: proficient producers of novel natural products with various biological activities--past and future biotechnological aspects with the focus on the genus Sorangium

21 January 2018

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Investigation of the early stages in soraphen A biosynthesis

21 January 2018

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Novel soraphens from precursor directed biosynthesis

21 January 2018

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Amphidinolides, bioactive macrolides from symbiotic marine dinoflagellates

21 January 2018

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Amphidinolides T2, T3, and T4, new 19-membered macrolides from the dinoflagellate Amphidinium sp. and the biosynthesis of amphidinolide T1.

21 January 2018

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Biosynthetic study of amphidinolide W.

21 January 2018

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Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa

21 January 2018

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A cluster of genes for the biosynthesis of spinosyns, novel macrolide insect control agents produced by Saccharopolyspora spinosa.

21 January 2018

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Rhamnose biosynthesis pathway supplies precursors for primary and secondary metabolism in Saccharopolyspora spinosa

21 January 2018

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Genes for the biosynthesis of spinosyns: applications for yield improvement in Saccharopolyspora spinosa

21 January 2018

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Engineered biosynthesis of novel spinosyns bearing altered deoxyhexose substituents

21 January 2018

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Organization of biosynthetic gene cluster for avermectin in Streptomyces avermitilis: analysis of enzymatic domains in four polyketide synthases

21 January 2018

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A second branched-chain alpha-keto acid dehydrogenase gene cluster (bkdFGH) from Streptomyces avermitilis: its relationship to avermectin biosynthesis and the construction of a bkdF mutant suitable for the production of novel antiparasitic avermecti

21 January 2018

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A novel delta(3),delta(2)-enoyl-CoA isomerase involved in the biosynthesis of the cyclohexanecarboxylic acid-derived moiety of the polyketide ansatrienin A.

21 January 2018

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Identification of a cyclohexylcarbonyl CoA biosynthetic gene cluster and application in the production of doramectin

21 January 2018

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Engineering of complex polyketide biosynthesis--insights from sequencing of the monensin biosynthetic gene cluster

21 January 2018

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Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization

21 January 2018

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Accumulation of an E,E,E-triene by the monensin-producing polyketide synthase when oxidative cyclization is blocked

21 January 2018

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Precursor supply for polyketide biosynthesis: the role of crotonyl-CoA reductase

21 January 2018

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'Streptomyces nanchangensis', a producer of the insecticidal polyether antibiotic nanchangmycin and the antiparasitic macrolide meilingmycin, contains multiple polyketide gene clusters

21 January 2018

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A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin

21 January 2018

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Macrotetrolide biosynthesis: a novel type II polyketide synthase

21 January 2018

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Genetic localization and molecular characterization of the nonS gene required for macrotetrolide biosynthesis in Streptomyces griseus DSM40695.

21 January 2018

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Cloning and heterologous expression of the macrotetrolide biosynthetic gene cluster revealed a novel polyketide synthase that lacks an acyl carrier protein

21 January 2018

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C-O bond formation by polyketide synthases

21 January 2018

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Nonactin biosynthesis: the initial committed step is the condensation of acetate (malonate) and succinate

21 January 2018

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Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes

21 January 2018

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Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.

21 January 2018

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The candicidin gene cluster from Streptomyces griseus IMRU 3570.

21 January 2018

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Organizational and mutational analysis of a complete FR-008/candicidin gene cluster encoding a structurally related polyene complex

21 January 2018

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Engineered biosynthesis of novel polyenes: a pimaricin derivative produced by targeted gene disruption in Streptomyces natalensis.

21 January 2018

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Enediyne Natural Products: Biosynthesis and Prospect Towards Engineering Novel Antitumor Agents

21 January 2018

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A genomics-guided approach for discovering and expressing cryptic metabolic pathways.

21 January 2018

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The calicheamicin gene cluster and its iterative type I enediyne PKS

21 January 2018

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The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases

21 January 2018

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Genes for production of the enediyne antitumor antibiotic C-1027 in Streptomyces globisporus are clustered with the cagA gene that encodes the C-1027 apoprotein

21 January 2018

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A novel 4-methylideneimidazole-5-one-containing tyrosine aminomutase in enediyne antitumor antibiotic C-1027 biosynthesis

21 January 2018

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Biosynthesis of the orthosomycin antibiotic avilamycin A: deductions from the molecular analysis of the avi biosynthetic gene cluster of Streptomyces viridochromogenes Tü57 and production of new antibiotics

21 January 2018

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Production of polyunsaturated fatty acids by polyketide synthases in both prokaryotes and eukaryotes

21 January 2018

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On the origin of deoxypentoses: evidence to support a glucose progenitor in the biosynthesis of calicheamicin

21 January 2018

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The first gene in the biosynthesis of the polyketide antibiotic TA of Myxococcus xanthus codes for a unique PKS module coupled to a peptide synthetase

21 January 2018

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Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.

21 January 2018

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Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.

21 January 2018

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Identification of stsC, the gene encoding the L-glutamine:scyllo-inosose aminotransferase from streptomycin-producing Streptomycetes

21 January 2018

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Biosynthesis of 1-deoxy-1-imino-D-erythrose 4-phosphate: a defining metabolite in the aminoshikimate pathway

21 January 2018

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Kanosamine biosynthesis: a likely source of the aminoshikimate pathway's nitrogen atom

21 January 2018

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Characterization of the early stage aminoshikimate pathway in the formation of 3-amino-5-hydroxybenzoic acid: the RifN protein specifically converts kanosamine into kanosamine 6-phosphate.

21 January 2018

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Recent developments in the maytansinoid antitumor agents

21 January 2018

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The loading module of rifamycin synthetase is an adenylation-thiolation didomain with substrate tolerance for substituted benzoates

21 January 2018

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The loading and initial elongation modules of rifamycin synthetase collaborate to produce mixed aryl ketide products

21 January 2018

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Engineered biosynthesis of an ansamycin polyketide precursor in Escherichia coli.

21 January 2018

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Molecular characterization and analysis of the biosynthetic gene cluster for the antitumor antibiotic mitomycin C from Streptomyces lavendulae NRRL 2564

21 January 2018

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Identification of a set of genes involved in the formation of the substrate for the incorporation of the unusual "glycolate" chain extension unit in ansamitocin biosynthesis

21 January 2018

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The Post-Polyketide Synthase Modification Steps in the Biosynthesis of the Antitumor Agent Ansamitocin by Actinosynnema pretiosum

21 January 2018

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Identification of asm19 as an acyltransferase attaching the biologically essential ester side chain of ansamitocins using N-desmethyl-4,5-desepoxymaytansinol, not maytansinol, as its substrate

21 January 2018

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Characterization of the cmcH genes of Nocardia lactamdurans and Streptomyces clavuligerus encoding a functional 3'-hydroxymethylcephem O-carbamoyltransferase for cephamycin biosynthesis

21 January 2018

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Identification of the novobiocin biosynthetic gene cluster of Streptomyces spheroides NCIB 11891

21 January 2018

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Genetics of zwittermicin a production by Bacillus cereus

21 January 2018

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Identification and characterization of the niddamycin polyketide synthase genes from Streptomyces caelestis

21 January 2018

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Crystal structure of an Acyl-ACP dehydrogenase from the FK520 polyketide biosynthetic pathway: insights into extender unit biosynthesis

21 January 2018

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A new substrate specificity for acyl transferase domains of the ascomycin polyketide synthase in Streptomyces hygroscopicus.

21 January 2018

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Production of a novel FK520 analog in Streptomyces hygroscopicus: improving titer while minimizing impurities

21 January 2018

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The biosynthetic gene cluster for the microtubule-stabilizing agents epothilones A and B from Sorangium cellulosum So ce90

21 January 2018

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Cloning and heterologous expression of the epothilone gene cluster.

21 January 2018

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Isolation and characterization of the epothilone biosynthetic gene cluster from Sorangium cellulosum

21 January 2018

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Heterologous expression of epothilone biosynthetic genes in Myxococcus xanthus

21 January 2018

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A new cytotoxic epothilone from modified polyketide synthases heterologously expressed in Myxococcus xanthus

21 January 2018

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Optimizing the heterologous production of epothilone D in Myxococcus xanthus

21 January 2018

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Large-scale isolation and crystallization of epothilone D from Myxococcus xanthus cultures

21 January 2018

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Control of secondary metabolite congener distributions via modulation of the dissolved oxygen tension.

21 January 2018

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Modulation of epothilone analog production through media design.

21 January 2018

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Epothilone biosynthesis: assembly of the methylthiazolylcarboxy starter unit on the EpoB subunit

21 January 2018

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Enzymatic assembly of epothilones: the EpoC subunit and reconstitution of the EpoA-ACP/B/C polyketide and nonribosomal peptide interfaces

21 January 2018

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Polyketide-nonribosomal peptide epothilone antitumor agents: the EpoA, B, C subunits

21 January 2018

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The barbamide biosynthetic gene cluster: a novel marine cyanobacterial system of mixed polyketide synthase (PKS)-non-ribosomal peptide synthetase (NRPS) origin involving an unusual trichloroleucyl starter unit

21 January 2018

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Analysis of the syrB and syrC genes of Pseudomonas syringae pv. syringae indicates that syringomycin is synthesized by a thiotemplate mechanism

21 January 2018

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The biosynthetic gene cluster for coronamic acid, an ethylcyclopropyl amino acid, contains genes homologous to amino acid-activating enzymes and thioesterases

21 January 2018

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The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase

21 January 2018

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The biosynthetic gene cluster for the anticancer drug bleomycin from Streptomyces verticillus ATCC15003 as a model for hybrid peptide-polyketide natural product biosynthesis

21 January 2018

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Cloning and characterization of the bleomycin biosynthetic gene cluster from Streptomyces verticillus ATCC15003.

21 January 2018

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Iron acquisition in plague: modular logic in enzymatic biogenesis of yersiniabactin by Yersinia pestis.

21 January 2018

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New lessons for combinatorial biosynthesis from myxobacteria. The myxothiazol biosynthetic gene cluster of Stigmatella aurantiaca DW4/3-1.

21 January 2018

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Cloning and characterization of a phosphopantetheinyl transferase from Streptomyces verticillus ATCC15003, the producer of the hybrid peptide-polyketide antitumor drug bleomycin

21 January 2018

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The biosynthesis of the aromatic myxobacterial electron transport inhibitor stigmatellin is directed by a novel type of modular polyketide synthase

21 January 2018

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Novel features in a combined polyketide synthase/non-ribosomal peptide synthetase: the myxalamid biosynthetic gene cluster of the myxobacterium Stigmatella aurantiaca Sga15.

21 January 2018

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Yersiniabactin synthetase: a four-protein assembly line producing the nonribosomal peptide/polyketide hybrid siderophore of Yersinia pestis

21 January 2018

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Expression, purification, and characterization of HMWP2, a 229 kDa, six domain protein subunit of Yersiniabactin synthetase

21 January 2018

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Acyl-CoA hydrolysis by the high molecular weight protein 1 subunit of yersiniabactin synthetase: mutational evidence for a cascade of four acyl-enzyme intermediates during hydrolytic editing

21 January 2018

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Yersiniabactin production requires the thioesterase domain of HMWP2 and YbtD, a putative phosphopantetheinylate transferase

21 January 2018

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Total structure determination of apratoxin A, a potent novel cytotoxin from the marine cyanobacterium Lyngbya majuscula

21 January 2018

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Characterization of the mupirocin biosynthesis gene cluster from Pseudomonas fluorescens NCIMB 10586.

21 January 2018

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Identification and localization of the gene cluster encoding biosynthesis of the antitumor macrolactam leinamycin in Streptomyces atroolivaceus S-140.

21 January 2018

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Type I polyketide synthase requiring a discrete acyltransferase for polyketide biosynthesis

21 January 2018

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Catalytic mapping of the vibriobactin biosynthetic enzyme VibF.

21 January 2018

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A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles

21 January 2018

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A multifunctional polyketide-peptide synthetase essential for albicidin biosynthesis in Xanthomonas albilineans

21 January 2018

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Allocation of pederin during lifetime ofPaederus rove beetles (Coleoptera: Staphylinidae): Evidence for polymorphism of hemolymph toxin

21 January 2018

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Suppression of pederin biosynthesis through antibiotic elimination of endosymbionts in Paederus sabaeus

21 January 2018

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Molecular identification of an endosymbiotic bacterium associated with pederin biosynthesis in Paederus sabaeus (Coleoptera: Staphylinidae).

21 January 2018

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Unprecedented diversity of catalytic domains in the first four modules of the putative pederin polyketide synthase

21 January 2018

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21 January 2018

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Mechanism of the beta-ketoacyl synthase reaction catalyzed by the animal fatty acid synthase

21 January 2018

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Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin

21 January 2018

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Genetic organization of the biosynthetic gene cluster for the antitumor angucycline oviedomycin in Streptomyces antibioticus ATCC 11891.

21 January 2018

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Cloning and functional analysis of a phosphopantetheinyl transferase superfamily gene associated with jadomycin biosynthesis in Streptomyces venezuelae ISP5230.

21 January 2018

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Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic

21 January 2018

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An acyl-coenzyme A carboxylase encoding gene associated with jadomycin biosynthesis in Streptomyces venezuelae ISP5230.

21 January 2018

1 reference

Cloning and characterization of a polyketide synthase gene cluster involved in biosynthesis of a proposed angucycline-like polyketide auricin in Streptomyces aureofaciens CCM 3239.

21 January 2018

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Elucidation of the function of two glycosyltransferase genes (lanGT1 and lanGT4) involved in landomycin biosynthesis and generation of new oligosaccharide antibiotics

21 January 2018

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Cloning of an avilamycin biosynthetic gene cluster from Streptomyces viridochromogenes Tü57.

21 January 2018

1 reference

The multifunctional 6-methylsalicylic acid synthase gene of Penicillium patulum. Its gene structure relative to that of other polyketide synthases

21 January 2018

1 reference

The mycarose-biosynthetic genes of Streptomyces fradiae, producer of tylosin

21 January 2018

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Analysis of a C-methyltransferase gene (aviG1) involved in avilamycin biosynthesis in Streptomyces viridochromogenes Tü57 and complementation of a Saccharopolyspora erythraea eryBIII mutant by aviG1.

21 January 2018

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Analysis of eryBI, eryBIII and eryBVII from the erythromycin biosynthetic gene cluster in Saccharopolyspora erythraea

21 January 2018

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Characterization of the biosynthetic gene cluster for the oligosaccharide antibiotic, Evernimicin, in Micromonospora carbonacea var. africana ATCC39149.

21 January 2018

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Enzyme reactions and genes in aflatoxin biosynthesis

21 January 2018

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Cloning, sequencing and analysis of the enterocin biosynthesis gene cluster from the marine isolate 'Streptomyces maritimus': evidence for the derailment of an aromatic polyketide synthase.

21 January 2018

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A mechanism of benzoic acid biosynthesis in plants and bacteria that mirrors fatty acid beta-oxidation.

21 January 2018

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Inactivation, complementation, and heterologous expression of encP, a novel bacterial phenylalanine ammonia-lyase gene.

21 January 2018

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Plant-like biosynthetic pathways in bacteria: from benzoic acid to chalcone

21 January 2018

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Aspects of the biosynthesis of non-aromatic fungal polyketides by iterative polyketide synthases.

21 January 2018

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Lovastatin biosynthesis in Aspergillus terreus: characterization of blocked mutants, enzyme activities and a multifunctional polyketide synthase gene

21 January 2018

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Monacolin N, a compound resulting from derailment of type I iterative polyketide synthase function en route to lovastatin

21 January 2018

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Conversion of cyclic nonaketides to lovastatin and compactin by a lovC deficient mutant of Aspergillus terreus.

21 January 2018

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Transformations of cyclic nonaketides by Aspergillus terreus mutants blocked for lovastatin biosynthesis at the lovA and lovC genes

21 January 2018

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Hexacyclinic acid, a Polyketide from Streptomyces with a Novel Carbon Skeleton We express our thanks to Hoechst AG (Frankfurt) for providing us with Streptomyces cellulosae (strain S 1013) and Mr. M. Decke for excellent technical assistance. We wish

21 January 2018

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A highly efficient synthesis of [1-13C, 18O]- and [1-13C, 2H2]-glycerol for the elucidation of biosynthetic pathways

21 January 2018

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Alternative modular polyketide synthase expression controls macrolactone structure

21 January 2018

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Lovastatin Nonaketide Synthase Catalyzes an Intramolecular Diels−Alder Reaction of a Substrate Analogue

21 January 2018

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Deletion of rapQONML from the rapamycin gene cluster of Streptomyces hygroscopicus gives production of the 16-O-desmethyl-27-desmethoxy analog.

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.54.250

Isolation and Structure Elucidation of Vicenistatin M, and Importance of the Vicenisamine Aminosugar for Exerting Cytotoxicity of Vicenistatin.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.54.211

The soraphens: a family of novel antifungal compounds from Sorangium cellulosum (Myxobacteria). I. Soraphen A1 alpha: fermentation, isolation, biological properties.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.47.23

Biosynthetic study of amphidinolide B

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1248/CPB.49.1366

Identifiers

DOI

10.1039/B301028G

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14 August 2017

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