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English
Ponatinib suppresses the development of myeloid and lymphoid malignancies associated with FGFR1 abnormalities
scientific article published on 11 July 2012
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Europe PubMed Central
PMCID
3629706
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22781593%20AND%20SRC:MED&resulttype=core&format=json
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7 February 2020
title
Ponatinib suppresses the development of myeloid and lymphoid malignancies associated with FGFR1 abnormalities
(English)
1 reference
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Europe PubMed Central
PMCID
3629706
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22781593%20AND%20SRC:MED&resulttype=core&format=json
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7 February 2020
author
John K. Cowell
series ordinal
4
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Europe PubMed Central
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3629706
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22781593%20AND%20SRC:MED&resulttype=core&format=json
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7 February 2020
author name string
M Ren
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1
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Europe PubMed Central
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3629706
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22781593%20AND%20SRC:MED&resulttype=core&format=json
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7 February 2020
H Qin
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2
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7 February 2020
R Ren
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3
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3629706
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7 February 2020
publication date
11 July 2012
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Europe PubMed Central
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3629706
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22781593%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
published in
Leukemia
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Europe PubMed Central
PMCID
3629706
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22781593%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
volume
27
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PMCID
3629706
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22781593%20AND%20SRC:MED&resulttype=core&format=json
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7 February 2020
page(s)
32-40
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3629706
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7 February 2020
issue
1
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Europe PubMed Central
PMCID
3629706
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22781593%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
exact match
https://scigraph.springernature.com/pub.10.1038/leu.2012.188
0 references
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Acute progression of BCR-FGFR1 induced murine B-lympho/myeloproliferative disorder suggests involvement of lineages at the pro-B cell stage.
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PubMed Central
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Ponatinib (AP24534), a multitargeted pan-FGFR inhibitor with activity in multiple FGFR-amplified or mutated cancer models
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Src activation plays an important key role in lymphomagenesis induced by FGFR1 fusion kinases
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The two faces of myeloproliferative neoplasms: Molecular events underlying lymphoid transformation.
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Constitutive Notch pathway activation in murine ZMYM2-FGFR1-induced T-cell lymphomas associated with atypical myeloproliferative disease
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The kinase inhibitor TKI258 is active against the novel CUX1-FGFR1 fusion detected in a patient with T-lymphoblastic leukemia/lymphoma and t(7;8)(q22;p11).
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AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance
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Soluble Ig-like transcript 3 inhibits tumor allograft rejection in humanized SCID mice and T cell responses in cancer patients.
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14-3-3 Integrates prosurvival signals mediated by the AKT and MAPK pathways in ZNF198-FGFR1-transformed hematopoietic cells
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PKC412 inhibits the zinc finger 198-fibroblast growth factor receptor 1 fusion tyrosine kinase and is active in treatment of stem cell myeloproliferative disorder
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Identifiers
DOI
10.1038/LEU.2012.188
1 reference
stated in
Europe PubMed Central
PMCID
3629706
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22781593%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
PMCID
3629706
1 reference
stated in
Europe PubMed Central
PMCID
3629706
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22781593%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
PubMed ID
22781593
1 reference
stated in
Europe PubMed Central
PMCID
3629706
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22781593%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 February 2020
ResearchGate publication ID
229064282
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