(Q36777331)

16 August 2017

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title

TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancer (English)

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16 August 2017

hepatocellular carcinoma

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Hussain SP

1

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16 August 2017

Schwank J

2

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16 August 2017

Staib F

3

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16 August 2017

Wang XW

4

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16 August 2017

Harris CC

5

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16 August 2017

language of work or name

English

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publication date

1 April 2007

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16 August 2017

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16 August 2017

26

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16 August 2017

2166-2176

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16 August 2017

15

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210279

16 August 2017

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cites work

Geographic variation of p53 mutational profile in nonmalignant human liver

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Aflatoxin B1 induces the transversion of G-->T in codon 249 of the p53 tumor suppressor gene in human hepatocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Hepatitis B virus X protein transactivates the inducible nitric oxide synthase promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Relationship between p53 mutations and inducible nitric oxide synthase expression in human colorectal cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Vascular endothelial growth factor and nitric oxide synthase expression in human lung cancer and the relation to p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Up-regulation of inducible nitric oxide synthase expression in cancer-prone p53 knockout mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Putative role of hepatitis B virus X protein in hepatocarcinogenesis: effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STAT pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Hepatitis B virus X protein interferes with cellular DNA repair.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Apoptosis of rat vascular smooth muscle cells is regulated by p53-dependent and -independent pathways.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

TIGAR, a p53-inducible regulator of glycolysis and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Molecular mechanisms underlying the development of hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Nitric oxide: a physiologic messenger molecule

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Connecting COX-2 and Wnt in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

The molecular signature of metastases of human hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Linear dose-response relationship for DNA adducts in rat liver from chronic exposure to aflatoxin B1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Knock-down of hepatitis B virus X protein reduces the tumorigenicity of hepatocellular carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines: initial analysis of the human NOS2 promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

CTNNB1 mutations and beta-catenin protein accumulation in human hepatocellular carcinomas associated with high exposure to aflatoxin B1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

NIH conference. Hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Hepatocellular carcinoma: an update

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Cellular response to gene expression profiles of different hepatitis C virus core proteins in the Huh-7 cell line with microarray analysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Regulation of human nitric oxide synthase 2 expression by Wnt beta-catenin signaling.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Rising incidence of hepatocellular carcinoma in the United States

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Hepatocellular carcinoma pathogenesis: from genes to environment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Cooperative interactions of p53 mutation, telomere dysfunction, and chronic liver damage in hepatocellular carcinoma progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Nitric oxide synthase: expression and expressional control of the three isoforms.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Significant correlation of nitric oxide synthase activity and p53 gene mutation in stage I lung adenocarcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Hepatitis C virus core protein stimulates hepatocyte growth: correlation with upregulation of wnt-1 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Induction of tumor necrosis factor alpha production by human hepatocytes in chronic viral hepatitis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Downregulation of DNA excision repair by the hepatitis B virus-x protein occurs in p53-proficient and p53-deficient cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Differential gene expression between chronic hepatitis B and C hepatic lesion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Mutational hot spot in the p53 gene in human hepatocellular carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Hepatitis B virus X mutants derived from human hepatocellular carcinoma retain the ability to abrogate p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

p53-induced up-regulation of MnSOD and GPx but not catalase increases oxidative stress and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Tumor suppressor genes: at the crossroads of molecular carcinogenesis, molecular epidemiology and human risk assessment.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Radical causes of cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Hepatitis B virus X protein inhibits nucleotide excision repair

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Chronic hepatitis C virus infection in humans: induction of hepatic nitric oxide synthase and proposed mechanisms for carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Synergistic interaction between aflatoxin B1 and hepatitis B virus in hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Ser-249 p53 mutations in plasma DNA of patients with hepatocellular carcinoma from The Gambia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

249(ser) TP53 mutation in plasma DNA, hepatitis B viral infection, and risk of hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Iron, hemochromatosis, and hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Specific mutations of hepatitis B virus in plasma predict liver cancer development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Hepatitis B 1762T/1764A mutations, hepatitis C infection, and codon 249 p53 mutations in hepatocellular carcinomas from Thailand

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Role of inflammatory cytokines and nitric oxide in hepatic and pulmonary toxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Comparative and integrative functional genomics of HCC.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Transcriptional repression of the human p53 gene by hepatitis B viral X protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Aberrations of p53 gene in human hepatocellular carcinoma from China.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Woodchuck hepatitis virus surface antigen induces nitric oxide synthesis in hepatocytes: possible role in hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Hepatitis B virus X protein activates transcription factor NF-kappa B without a requirement for protein kinase C

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Aflatoxin B1-induced DNA adduct formation and p53 mutations in CYP450-expressing human liver cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Altered DNA mutation spectrum in aflatoxin b1-treated transgenic mice that express the hepatitis B virus x protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Inducible nitric oxide synthase expression in chronic viral hepatitis. Evidence for a virus-induced gene upregulation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Oxidative stress and p53 mutations in the carcinogenesis of iron overload-associated hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Expression of hepatitis B virus X oncoprotein inhibits transcription-coupled nucleotide excision repair in human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Nitric oxide-induced apoptosis: p53-dependent and p53-independent signalling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

High inflammatory activity is associated with an increased amount of IFN-gamma transcripts in peripheral blood cells of patients with chronic hepatitis C virus infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Dominant role of hepatitis B virus and cofactor role of aflatoxin in hepatocarcinogenesis in Qidong, China

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Progressive telomere shortening and telomerase reactivation during hepatocellular carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Hepatitis B virus X protein: a multifunctional viral regulator

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Nitric oxide synthases: roles, tolls, and controls

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Gene expression profile linked to p53 status in hepatitis C virus-related hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

p53 mutation in hepatocellular carcinoma after aflatoxin exposure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Global cancer statistics, 2002

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Estimates of the worldwide mortality from 25 cancers in 1990.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

p53-mediated cellular response to DNA damage in cells with replicative hepatitis B virus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Hepatitis B virus transactivator protein, HBx, associates with the components of TFIIH and stimulates the DNA helicase activity of TFIIH

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Urinary aflatoxin biomarkers and risk of hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

The antioxidant function of the p53 tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

p53: traffic cop at the crossroads of DNA repair and recombination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Insights into the Pathobiology of Hepatitis C Virus-Associated Cirrhosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

TP53 and liver carcinogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

The p53 tumor suppressor network is a key responder to microenvironmental components of chronic inflammatory stress.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Transcriptional activation of the human glutathione peroxidase promoter by p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Molecular functions and biological roles of hepatitis B virus x protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Molecular pathogenesis of human hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Aflatoxin-B exposure does not lead to p53 mutations but results in enhanced liver cancer of Hupki (human p53 knock-in) mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Functional inactivation but not structural mutation of p53 causes liver cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Genetic heterogeneity of hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Inflammatory modulation of hepatocyte apoptosis by nitric oxide: in vivo, in vitro, and in silico studies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Molecular pathogenesis of human hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Monitoring of individual human exposure to aflatoxins (AF) and N-nitrosamines (NNO) by immunoassays

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Cloning and characterization of inducible nitric oxide synthase from mouse macrophages

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Environmental factors and risk for hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210279

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210279

1 reference

Dimensions Publication ID

16 August 2017

0 references

1 reference