(Q33926143)

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Putative role of hepatitis B virus X protein in hepatocarcinogenesis: effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STAT pathways

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 July 2017

1 reference

Europe PubMed Central

Putative role of hepatitis B virus X protein in hepatocarcinogenesis: effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STAT pathways (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

apoptotic process

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Hepatitis B virus

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

P Arbuthnot

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

A Capovilla

2

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

M Kew

3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 April 2000

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Journal of Gastroenterology and Hepatology

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

15

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

357-368

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Hepatocellular carcinoma and hepatitis B virus. A prospective study of 22 707 men in Taiwan

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Molecular events in the pathogenesis of hepadnavirus-associated hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Hepatitis B virus infection and primary hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Asymmetric replication of duck hepatitis B virus DNA in liver cells: Free minus-strand DNA

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Evidence for supercoiled hepatitis B virus DNA in chimpanzee liver and serum Dane particles: possible implications in persistent HBV infection

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Experimental transmission of duck hepatitis B virus

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Biochemical and genetic evidence for the hepatitis B virus replication strategy

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Common evolutionary origin of hepatitis B virus and retroviruses

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

HBx gene of hepatitis B virus induces liver cancer in transgenic mice

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

High-level expression of hepatitis B virus HBx gene and hepatocarcinogenesis in transgenic mice

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Hepatitis B virus HBx gene and hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

The hepatitis B virus X gene potentiates c-myc-induced liver oncogenesis in transgenic mice

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Integration of region X of hepatitis B virus genome in human primary hepatocellular carcinomas propagated in nude mice

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Expression of hepatitis B virus X protein in HBV-infected human livers and hepatocellular carcinomas

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Cytosol is the prime compartment of hepatitis B virus X protein where it colocalizes with the proteasome

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Mouse monoclonal antibody directed against hepatitis B virus X protein synthesized in Escherichia coli: detection of reactive antigen in liver cell carcinoma and chronic hepatitis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Expression of X protein and hepatitis B virus replication in chronic hepatitis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Human hepatitis B virus X protein is detectable in nuclei of transfected cells, and is active for transactivation

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Use of the polymerase chain reaction for the sensitive detection of St. Louis encephalitis viral RNA

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Hepadnaviral X Protein:Review of Recent Progress

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Diverse molecular provocation of programmed cell death

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Apoptosis by death factor

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Daxx, a novel Fas-binding protein that activates JNK and apoptosis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Bcl-2 and the regulation of programmed cell death

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Life, death, and the pursuit of apoptosis.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

A model for p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Mdm2 promotes the rapid degradation of p53

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Regulation of p53 stability by Mdm2

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Apoptosis and viral hepatitis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Viral Clearance Without Destruction of Infected Cells During Acute HBV Infection

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

X protein of hepatitis B virus resembles a serine protease inhibitor

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

The hepatitis B virus HBx protein inhibits caspase 3 activity.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Pro-apoptotic effect of the hepatitis B virus X gene.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

p53-independent apoptotic effects of the hepatitis B virus HBx protein in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Hepatitis B virus HBx protein sensitizes cells to apoptotic killing by tumor necrosis factor alpha

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Increased production of tumour necrosis factor alpha in chronic hepatitis B virus infection

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Tumor necrosis factor alpha production by peripheral blood mononuclear cells of patients with chronic liver disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Increased tumor necrosis factor-alpha receptor number in chronic hepatitis B virus infection

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

X-gene product of hepatitis B virus induces apoptosis in liver cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Association of human papillomavirus types 16 and 18 E6 proteins with p53.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Hepatitis B virus X protein partially substitutes for E1A transcriptional function during adenovirus infection

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Full-length and truncated versions of the hepatitis B virus (HBV) X protein (pX) transactivate the cmyc protooncogene at the transcriptional level

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Functional inactivation but not structural mutation of p53 causes liver cancer.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Disruption of the function of tumor-suppressor gene p53 by the hepatitis B virus X protein and hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

The C-terminal domain of p53 recognizes DNA damaged by ionizing radiation

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

p53 domains: identification and characterization of two autonomous DNA-binding regions.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Conservation of eukaryotic DNA repair mechanisms.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Nucleotide excision repair in mammalian cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

p53 modulation of TFIIH-associated nucleotide excision repair activity

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Purification and characterization of a human protein that binds to damaged DNA.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Correction of the DNA repair defect in xeroderma pigmentosum group E by injection of a DNA damage-binding protein

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Mammalian DNA nucleotide excision repair reconstituted with purified protein components.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Hepatitis B x protein inhibits p53-dependent DNA repair in primary mouse hepatocytes

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Hepatitis B virus X protein inhibits nucleotide excision repair

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Downregulation of DNA excision repair by the hepatitis B virus-x protein occurs in p53-proficient and p53-deficient cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Hepatitis B virus X-protein binds damaged DNA and sensitizes liver cells to ultraviolet irradiation

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Apolipoprotein B gene regulatory factor-2 (BRF-2) is structurally and immunologically highly related to hepatitis B virus X associated protein-1 (XAP-1).

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

DDB, a putative DNA repair protein, can function as a transcriptional partner of E2F1.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Hepatitis B virus transactivator protein, HBx, associates with the components of TFIIH and stimulates the DNA helicase activity of TFIIH

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Genetic dissection of a neurodevelopmental pathway: Son of sevenless functions downstream of the sevenless and EGF receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Increasing complexity of Ras signaling.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Hepatitis B virus transactivator HBx uses a tumour promoter signalling pathway

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

The hepatitis B virus transactivator HBx causes elevation of diacylglycerol and activation of protein kinase C.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Transactivation by hepatitis B virus X protein is promiscuous and dependent on mitogen-activated cellular serine/threonine kinases.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Transactivation of human hepatitis B virus X protein, HBx, operates through a mechanism distinct from protein kinase C and okadaic acid activation pathways

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras, Raf, MAP kinase signaling cascade

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Erk-independent partial activation of AP-1 sites by the hepatitis B virus HBx protein

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Activation of Src family kinases by hepatitis B virus HBx protein and coupled signaling to Ras

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Cellular functions regulated by Src family kinases

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Hepatitis B virus HBx protein deregulates cell cycle checkpoint controls

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Constitutive activation of JAK1 in Src-transformed cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

The structure, regulation and function of the Janus kinases (JAKs) and the signal transducers and activators of transcription (STATs).

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Jaks and STATs: biological implications

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Cellular responses to interferons and other cytokines: the JAK-STAT paradigm

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

HBx protein of hepatitis B virus activates Jak1-STAT signaling

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Epidermal growth factor induces the tyrosine phosphorylation and nuclear translocation of Stat 5 in mouse liver

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

The hepatitis B virus

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

A cellular poison cupboard

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1746.2000.02069.X

21 January 2018

Identifiers

10.1046/J.1440-1746.2000.02069.X

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

release_xmyxdt44kjfg3cbsxizfdslt4m

1 reference

https://api.fatcat.wiki/v0/release/xmyxdt44kjfg3cbsxizfdslt4m

24 November 2022

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mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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