(Q41135422)

English

Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling

scientific article published on September 1996

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scholarly article

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Europe PubMed Central

27 September 2017

1 reference

Europe PubMed Central

Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling (English)

1 reference

Europe PubMed Central

27 September 2017

phosphorylation

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based on heuristic

inferred from title

author name string

Denhardt DT

1

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Europe PubMed Central

27 September 2017

language of work or name

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publication date

1 September 1996

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Europe PubMed Central

27 September 2017

Biochemical Journal

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Europe PubMed Central

27 September 2017

318 ( Pt 3)

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Europe PubMed Central

27 September 2017

729-747

1 reference

Europe PubMed Central

27 September 2017

Ste5: a meeting place for MAP kinases and their associates

1 reference

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1 reference

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Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation.

1 reference

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Identification of novel phosphorylation sites required for activation of MAPKAP kinase-2

1 reference

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Protein kinase C and its substrates

1 reference

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Activation of the JNK pathway by distantly related protein kinases, MEKK and MUK

1 reference

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Activated Ras displaces 14-3-3 protein from the amino terminus of c-Raf-1

1 reference

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Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase

1 reference

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Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformation

1 reference

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Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase

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Molecular cloning and sequencing of the cytostatic G protein-activated protein kinase PAK I.

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MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

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Ras-induced activation of Raf-1 is dependent on tyrosine phosphorylation

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Selective activation of MEK1 but not MEK2 by A-Raf from epidermal growth factor-stimulated Hela cells

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Characterization of the structure and function of a novel MAP kinase kinase (MKK6)

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Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase

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Active and inactive protein kinases: structural basis for regulation

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The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling

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Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast

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Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine

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Recognition and specificity in protein tyrosine kinase-mediated signalling

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A putative effector of Ral has homology to Rho/Rac GTPase activating proteins

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Complete nucleotide sequence, expression, and chromosomal localisation of human mixed-lineage kinase 2

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Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

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Dominant-negative mutants of Grb2 induced reversal of the transformed phenotypes caused by the point mutation-activated rat HER-2/Neu

1 reference

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Cysteine-rich region of Raf-1 interacts with activator domain of post-translationally modified Ha-Ras

1 reference

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Interactions between the protein-tyrosine kinase ZAP-70, the proto-oncoprotein Vav, and tubulin in Jurkat T cells

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A role for Rho in Ras transformation

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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Structure and ligand recognition of the phosphotyrosine binding domain of Shc

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p95vav associates with the nuclear protein Ku-70

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KSR, a novel protein kinase required for RAS signal transduction

1 reference

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Structural requirements for the interaction of p21ras with GAP, exchange factors, and its biological effector target

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Ras-responsive genes and tumor metastasis

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Raf-1 protein kinase activates the NF-kappa B transcription factor by dissociating the cytoplasmic NF-kappa B-I kappa B complex

1 reference

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Signal transduction via the MAP kinases: proceed at your own RSK.

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Non-nuclear oncogenes and the regulation of gene expression in transformed cells.

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Function and regulation of ras.

1 reference

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The N-terminal region of GAP regulates cytoskeletal structure and cell adhesion

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The GRB2/Sem-5 adaptor protein

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Neurofibromin can inhibit Ras-dependent growth by a mechanism independent of its GTPase-accelerating function

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Epidermal growth factor induces phosphorylation of extracellular signal-regulated kinase 2 via multiple pathways

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The PH domain: a common piece in the structural patchwork of signalling proteins

1 reference

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Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

1 reference

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Ligation of the T cell receptor complex results in activation of the Ras/Raf-1/MEK/MAPK cascade in human T lymphocytes

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The Ras signal transduction pathway

1 reference

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

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Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues.

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A brain serine/threonine protein kinase activated by Cdc42 and Rac1

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Regulation of Ras signal transduction in normal and transformed cells

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Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate.

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G protein pathways: signal processing by effectors

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Transformation of mammalian cells by constitutively active MAP kinase kinase

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Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

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Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

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Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

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Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

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GTPases: multifunctional molecular switches regulating vesicular traffic

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Mechanisms of intracellular protein transport

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RAS and RAF-1 form a signalling complex with MEK-1 but not MEK-2.

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Cloning and characterization of p97MAPK, a novel human homolog of rat ERK-3

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A novel oncogene, ost, encodes a guanine nucleotide exchange factor that potentially links Rho and Rac signaling pathways

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The mitogen-activated protein kinase cascade is activated by B-Raf in response to nerve growth factor through interaction with p21ras

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A novel mammalian Ras GTPase-activating protein which has phospholipid-binding and Btk homology regions

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Overexpression of mitogen-activated protein kinase kinase (MAPKK) and its mutants in NIH 3T3 cells. Evidence that MAPKK involvement in cellular proliferation is regulated by phosphorylation of serine residues in its kinase subdomains VII and VIII

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Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway.

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Signal transduction pathways involving Ras. Mini review

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Receptor protein-tyrosine kinases and their signal transduction pathways

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Regulation of Raf-1 kinase activity by the 14-3-3 family of proteins

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Regulation of Ras-mediated signalling: more than one way to skin a cat.

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Binding of NCK to SOS and activation of ras-dependent gene expression

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The ins and outs of Raf kinases

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Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

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27 September 2017

Phospholipid signaling

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27 September 2017

Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling

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Dimerization of cell surface receptors in signal transduction

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Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

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27 September 2017

Activation of Raf as a result of recruitment to the plasma membrane

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Modulation of cellular thermoresistance and actin filament stability accompanies phosphorylation-induced changes in the oligomeric structure of heat shock protein 27

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Ras-dependent and -independent pathways target the mitogen-activated protein kinase network in macrophages.

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Platelet-derived growth factor receptor signals

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27 September 2017

How MAP kinases are regulated

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Expression of the neurofibromatosis 1 (NF1) isoforms in developing and adult rat tissues.

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Guanine nucleotide exchange factors: activators of the Ras superfamily of proteins

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G beta gamma interactions with PH domains and Ras-MAPK signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

14-3-3 is not essential for Raf-1 function: identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Rho-related proteins: actin cytoskeleton and cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Raf1 interaction with Cdc25 phosphatase ties mitogenic signal transduction to cell cycle activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

GTPase cascades choreographing cellular behavior: movement, morphogenesis, and more

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Parallel signal processing among mammalian MAPKs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Biochemical analysis of MEK activation in NIH3T3 fibroblasts. Identification of B-Raf and other activators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

An emerging family of dual specificity MAP kinase phosphatases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Loss of neurofibromin results in neurotrophin-independent survival of embryonic sensory and sympathetic neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

CDC25 phosphatases as potential human oncogenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Rho family members: activators of MAP kinase cascades.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Rapid induction of heparin-binding epidermal growth factor/diphtheria toxin receptor expression by Raf and Ras oncogenes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Identification of a specific Ins(1,3,4,5)P4-binding protein as a member of the GAP1 family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

The regulation of tyrosine kinase signalling pathways by growth factor and G-protein-coupled receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Regulation of human leukocyte p21-activated kinases through G protein--coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Significance of PIP2 hydrolysis and regulation of phospholipase C isozymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Src family protein tyrosine kinases and cellular signal transduction pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Reversal of Raf-1 activation by purified and membrane-associated protein phosphatases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

The family of G-protein-coupled receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

The MAPK signaling cascade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

A single point mutation switches the specificity of group III Src homology (SH) 2 domains to that of group I SH2 domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Differential activation of c-fos promoter elements by serum, lysophosphatidic acid, G proteins and polypeptide growth factors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Journey to the surface of the cell: Fos regulation and the SRE.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Bcr and Raf form a complex in vivo via 14-3-3 proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Structure of the binding site for inositol phosphates in a PH domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Serine/threonine protein phosphatases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

G protein beta gamma subunits stimulate phosphorylation of Shc adapter protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Cytokine receptor signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Differential regulation of Raf-1 and B-Raf and Ras-dependent activation of mitogen-activated protein kinase by cyclic AMP in PC12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

A proline-rich sequence unique to MEK1 and MEK2 is required for raf binding and regulates MEK function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Shc and a novel 89-kDa component couple to the Grb2-Sos complex in fibroblast growth factor-2-stimulated cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Ras target proteins in eukaryotic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

When is a lipid kinase not a lipid kinase? When it is a protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

The PTB domain: a new protein module implicated in signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Rho as a regulator of the cytoskeleton.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Measurement of the binding of tyrosyl phosphopeptides to SH2 domains: a reappraisal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Protein modules and signalling networks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

An alternative to SH2 domains for binding tyrosine-phosphorylated proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Epidermal growth factor-receptor mutant lacking the autophosphorylation sites induces phosphorylation of Shc protein and Shc-Grb2/ASH association and retains mitogenic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Isolation of MEK5 and differential expression of alternatively spliced forms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Protein kinase C: structure, function, and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Inhibition of phosphatidylinositol 3-kinase activity by association with 14-3-3 proteins in T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Regulation of the Ras signaling pathway by GTPase-activating protein in PC12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

MAP kinase phosphorylation of mSos1 promotes dissociation of mSos1-Shc and mSos1-EGF receptor complexes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Downregulation of the Ras activation pathway by MAP kinase phosphorylation of Sos.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Regulation of the Src tyrosine kinase and Syp tyrosine phosphatase by their cellular association.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Vascular system defects and neuronal apoptosis in mice lacking ras GTPase-activating protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Constitutively active MAP kinase kinase (MEK1) stimulates SAP kinase and c-Jun transcriptional activity in U937 human leukemic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

JAK2, Ras, and Raf are required for activation of extracellular signal-regulated kinase/mitogen-activated protein kinase by growth hormone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Selective activation of c-Jun kinase mitogen-activated protein kinase by CD40 on human B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Direct interaction between Ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

p21ras as a common signaling target of reactive free radicals and cellular redox stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Disruption of the Raf-1-Hsp90 molecular complex results in destabilization of Raf-1 and loss of Raf-1-Ras association

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Ras is not required for the interleukin 3-induced proliferation of a mouse pro-B cell line, BaF3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

c-Src phosphorylates epidermal growth factor receptor on tyrosine 845.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Evidence for cell-specific differences in transformation by N-, H- and K-ras

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Involvement of Ral GTPase in v-Src-induced phospholipase D activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Phosphorylation of Raf by ceramide-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

27 September 2017

Constitutively active mitogen-activated protein kinase kinase 1 (MAPKK1) and MAPKK2 mediate similar transcriptional and morphological responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

Ras interaction with two distinct binding domains in Raf-1 may be required for Ras transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

Cell type-specific modulation of cell growth by transforming growth factor beta 1 does not correlate with mitogen-activated protein kinase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

Differential modulation of mitogen-activated protein (MAP) kinase/extracellular signal-related kinase kinase and MAP kinase activities by a mutant epidermal growth factor receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

c-Abl activation regulates induction of the SEK1/stress-activated protein kinase pathway in the cellular response to 1-beta-D-arabinofuranosylcytosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

Transmembrane signaling by epidermal growth factor receptors lacking autophosphorylation sites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

Identification of the major phosphorylation sites of the Raf-1 kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

cAMP and beta gamma subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

Functional divergence of the MAP kinase pathway. ERK1 and ERK2 activate specific transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

Integrin-mediated cell adhesion activates mitogen-activated protein kinases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

Shc associates with an unphosphorylated form of the p21ras guanine nucleotide exchange factor mSOS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

Transforming G protein-coupled receptors potently activate JNK (SAPK). Evidence for a divergence from the tyrosine kinase signaling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

Inactivation of glycogen synthase kinase-3 by epidermal growth factor is mediated by mitogen-activated protein kinase/p90 ribosomal protein S6 kinase signaling pathway in NIH/3T3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

Raf phosphorylates p53 in vitro and potentiates p53-dependent transcriptional transactivation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

An essential role for Rac in Ras transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

Expression of a catalytically inert Syp blocks activation of MAP kinase pathway downstream of p21ras

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

Binding of Shc to the NPXY motif is mediated by its N-terminal domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

Evidence for a bifurcation of the mitogenic signaling pathway activated by Ras and phosphatidylcholine-hydrolyzing phospholipase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

Desensitization of Ras activation by a feedback disassociation of the SOS-Grb2 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

Interferon-induced nuclear signalling by Jak protein tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

v-src induces prostaglandin synthase 2 gene expression by activation of the c-Jun N-terminal kinase and the c-Jun transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

14 June 2018

Nerve growth factor-induced growth arrest and induction of p21Cip1/WAF1 in NIH-3T3 cells expressing TrkA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

17 June 2018

Characterization of the interaction between RhoGDI and Cdc42Hs using fluorescence spectroscopy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

19 August 2018

SOS phosphorylation and disassociation of the Grb2-SOS complex by the ERK and JNK signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

19 August 2018

Mammalian SH2-containing protein tyrosine phosphatases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

19 August 2018

Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

19 August 2018

Syp (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

19 August 2018

Mechanism of inhibition of Raf-1 by protein kinase A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

19 August 2018

Phosphorylation and activation of p90rsk by glycogen synthase kinase-3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

19 August 2018

Lack of evidence for the activation of the Ras/Raf mitogenic pathway by 14-3-3 proteins in mammalian cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

19 August 2018

Glycogen synthase kinase-3 beta is a dual specificity kinase differentially regulated by tyrosine and serine/threonine phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

19 August 2018

Differential Activation of PKC Isozymes by 14-3-3 ζ Protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1217680

2 December 2018

Participation of reactive oxygen species in the lysophosphatidic acid-stimulated mitogen-activated protein kinase kinase activation pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/8836113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

14-3-3 proteins on the MAP

1 reference

https://pubmed.ncbi.nlm.nih.gov/8836113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the mitogen-activated protein kinase signaling pathway in neutrophils. Role of oxidants

1 reference

https://pubmed.ncbi.nlm.nih.gov/8836113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ceramide activates the stress-activated protein kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/8836113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol (3,4,5)P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/8836113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 activates p54 mitogen-activated protein (MAP) kinase/stress-activated protein kinase by a pathway that is independent of p21ras, Raf-1, and MAP kinase kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8836113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disassembly of Son-of-sevenless proteins from Grb2 during p21ras desensitization by insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8836113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of p90RSK as the probable CREB-Ser133 kinase in human melanocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8836113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G beta gamma subunits mediate mitogen-activated protein kinase activation by the tyrosine kinase insulin-like growth factor 1 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/8836113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preferential involvement of MEK1 in the tumor necrosis factor-alpha-induced activation of p42mapk/erk2 in mouse macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/8836113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phosphotyrosine interaction domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/8836113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A secondary phosphorylation of CREB341 at Ser129 is required for the cAMP-mediated control of gene expression. A role for glycogen synthase kinase-3 in the control of gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/8836113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A conserved region of c-Ha-Ras is required for efficient GTPase stimulation by GTPase activating protein but not neurofibromin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8836113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual effect of beta-adrenergic receptors on mitogen-activated protein kinase. Evidence for a beta gamma-dependent activation and a G alpha s-cAMP-mediated inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/8836113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of p38 mitogen-activated protein kinase by insulin in cultured fetal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/8836113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations that abolish the ability of Ha-Ras to associate with Raf-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/8836113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein phosphatases

1 reference

https://pubmed.ncbi.nlm.nih.gov/8836113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ras-dependent growth factor regulation of MEK kinase in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8836113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/8836113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human mitogen-activated protein kinase CSBP1, but not CSBP2, complements a hog1 deletion in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/8836113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of protein kinase cascades by osmotic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/8836113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ3180729

1 reference

Europe PubMed Central

27 September 2017

release_accwmb5vxjan3hqovdatn7aixq

1 reference

https://api.fatcat.wiki/v0/release/accwmb5vxjan3hqovdatn7aixq

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

27 September 2017

1 reference

Europe PubMed Central

27 September 2017

ResearchGate publication ID

0 references

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