(Q36782842)

16 August 2017

Monitoring Ligand-Induced Protein Ordering in Drug Discovery (English)

1 reference

16 August 2017

1 reference

10

R Kiplin Guy

1 reference

16 August 2017

Christy R Grace

1

1 reference

16 August 2017

David Ban

2

1 reference

16 August 2017

Jaeki Min

3

1 reference

16 August 2017

Anand Mayasundari

4

1 reference

16 August 2017

Lie Min

5

1 reference

16 August 2017

Kristin E Finch

6

1 reference

16 August 2017

Lyra Griffiths

7

1 reference

16 August 2017

Nagakumar Bharatham

8

1 reference

16 August 2017

Donald Bashford

9

1 reference

16 August 2017

Michael A Dyer

11

1 reference

16 August 2017

Richard W Kriwacki

12

1 reference

16 August 2017

language of work or name

English

0 references

publication date

23 January 2016

1 reference

Journal of Molecular Biology

16 August 2017

1 reference

16 August 2017

428

1 reference

16 August 2017

6

1 reference

16 August 2017

1290-1303

1 reference

Disorder and residual helicity alter p53-Mdm2 binding affinity and signaling in cells

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

Organocatalytic, diastereo- and enantioselective synthesis of nonsymmetric cis-stilbene diamines: a platform for the preparation of single-enantiomer cis-imidazolines for protein-protein inhibition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

Ligand binding mode prediction by docking: mdm2/mdmx inhibitors as a case study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

MDM2, MDMX and p53 in oncogenesis and cancer therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

Ordering of the N-terminus of human MDM2 by small molecule inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

Quantitative analysis of multisite protein-ligand interactions by NMR: binding of intrinsically disordered p53 transactivation subdomains with the TAZ2 domain of CBP.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

The structure-based design of Mdm2/Mdmx-p53 inhibitors gets serious

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

MDM4 binds ligands via a mechanism in which disordered regions become structured

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

Structure-based Design of High Affinity Peptides Inhibiting the Interaction of p53 with MDM2 and MDMX

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

A thermodynamic approach to the affinity optimization of drug candidates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

Fast and accurate predictions of protein NMR chemical shifts from interatomic distances.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

Consistent blind protein structure generation from NMR chemical shift data

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

Molecular basis for the inhibition of p53 by Mdmx

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

Efficient p53 activation and apoptosis by simultaneous disruption of binding to MDM2 and MDMX

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

A new model for chemical shifts of amide hydrogens in proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

A simple method to predict protein flexibility using secondary chemical shifts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

Close agreement between the orientation dependence of hydrogen bonds observed in protein structures and quantum mechanical calculations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

p27 binds cyclin-CDK complexes through a sequential mechanism involving binding-induced protein folding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

Rapid and accurate calculation of protein 1H, 13C and 15N chemical shifts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

Three-dimensional hydrogen-bond geometry and probability information from a crystal survey

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

Coupling of local folding to site-specific binding of proteins to DNA

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

Inactivation of the p53 pathway in retinoblastoma.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826315

Accuracy and precision of protein-ligand interaction kinetics determined from chemical shift titrations

27 June 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26812210

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Comparative study of the p53-mdm2 and p53-MDMX interfaces

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26812210

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

NMR structure of a complex between MDM2 and a small molecule inhibitor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26812210

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.JMB.2016.01.016

1 reference

16 August 2017

1 reference

16 August 2017

1 reference