(Q36787240)

16 August 2017

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title

Proteomics of Alzheimer's disease: understanding mechanisms and seeking biomarkers (English)

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16 August 2017

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Steven Lynham

4

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Malcolm A Ward

object named as

Malcolm Ward

6

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Simon Lovestone

object named as

Simon Lovestone

1

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Madhav Thambisetty

5

object named as

Madhav Thambisetty

1 reference

16 August 2017

Andreas Güntert

2

1 reference

16 August 2017

Abdul Hye

3

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16 August 2017

publication date

1 April 2007

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Expert Review of Proteomics

16 August 2017

published in

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16 August 2017

volume

4

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16 August 2017

issue

2

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16 August 2017

page(s)

227-238

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Alzheimer's disease in the UK: comparative evidence on cost of illness and volume of health services research funding.

16 August 2017

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21 January 2018

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21 January 2018

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Proteomics in Alzheimer's disease: insights into potential mechanisms of neurodegeneration

21 January 2018

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Proteomic identification of nitrated proteins in Alzheimer's disease brain

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21 January 2018

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Post-translational modifications of tau protein in Alzheimer's disease

21 January 2018

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21 January 2018

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New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry

21 January 2018

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Phosphorylation of tau protein to sites found in Alzheimer's disease brain is catalyzed by Ca2+/calmodulin-dependent protein kinase II as demonstrated tandem mass spectrometry

21 January 2018

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Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase.

21 January 2018

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Phosphorylation Sites on Tau Identified by Nanoelectrospray Mass Spectrometry

21 January 2018

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Characterization of the in vitro phosphorylation of human tau by tau protein kinase II (cdk5/p20) using mass spectrometry

21 January 2018

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Proteomic identification of proteins specifically oxidized by intracerebral injection of amyloid beta-peptide (1-42) into rat brain: implications for Alzheimer's disease

21 January 2018

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Quantitative proteomics analysis of specific protein expression and oxidative modification in aged senescence-accelerated-prone 8 mice brain

21 January 2018

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The critical role of methionine 35 in Alzheimer's amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity

21 January 2018

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Increased oxidative stress in Alzheimer's disease as assessed with 4-hydroxynonenal but not malondialdehyde

21 January 2018

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21 January 2018

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21 January 2018

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Redox proteomics identification of oxidized proteins in Alzheimer's disease hippocampus and cerebellum: an approach to understand pathological and biochemical alterations in AD.

21 January 2018

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Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1.

21 January 2018

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The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: the role of Abeta1-42.

21 January 2018

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Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: insights into the development of Alzheimer's disease

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Identification of proteins in human cerebrospinal fluid using liquid-phase isoelectric focusing as a prefractionation step followed by two-dimensional gel electrophoresis and matrix-assisted laser desorption/ionisation mass spectrometry

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Proteomic identification of lower apolipoprotein A-I in Alzheimer's disease.

21 January 2018

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21 January 2018

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Amyloid beta peptides in cerebrospinal fluid as profiled with surface enhanced laser desorption/ionization time-of-flight mass spectrometry: evidence of novel biomarkers in Alzheimer's disease

21 January 2018

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Cerebrospinal fluid profile of amyloid beta peptides in patients with Alzheimer's disease determined by protein biochip technology

21 January 2018

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Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease

21 January 2018

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https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Analysis of glial acidic fibrillary protein in the human entorhinal cortex during aging and in Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Occurrence of interleukin-6 in cortical plaques of Alzheimer's disease patients may precede transformation of diffuse into neuritic plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Insulin-degrading enzyme in the Alzheimer's disease brain: prominent localization in neurons and senile plaques

21 January 2018

1 reference

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α2-macroglobulin expression in neuritic-type plaques in patients with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Active caspase-6 and caspase-6-cleaved tau in neuropil threads, neuritic plaques, and neurofibrillary tangles of Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Quantification of the A beta peptide in Alzheimer's plaques by laser dissection microscopy combined with mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Synaptophysin and chromogranin A immunoreactivities in senile plaques of Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1586%2F14789450.4.2.227

NDRG2: a novel Alzheimer's disease associated protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Tomoregulin-2 is found extensively in plaques in Alzheimer's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Induction of brain-derived neurotrophic factor in plaque-associated glial cells of aged APP23 transgenic mice.

21 January 2018

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https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Fibroblast growth factor (FGF)-9 immunoreactivity in senile plaques

21 January 2018

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Midkine, a novel neurotrophic factor, is present in senile plaques of Alzheimer disease

21 January 2018

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Immunoreactive epidermal growth factor receptors in neuritic plaques from patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Somatostatin immunoreactivity in neuritic plaques of Alzheimer's patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Copper, iron and zinc in Alzheimer's disease senile plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Histological co-localization of iron in Abeta plaques of PS/APP transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Histochemically-reactive zinc in amyloid plaques, angiopathy, and degenerating neurons of Alzheimer's diseased brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Ferritin is a component of the neuritic (senile) plaque in Alzheimer dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Co-localization of cholesterol, apolipoprotein E and fibrillar Abeta in amyloid plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Inducible nitric oxide synthase immunoreactivity in the Alzheimer disease hippocampus: association with Hirano bodies, neurofibrillary tangles, and senile plaques.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

NF-kB immunoreactivity is observed in association with beta A4 diffuse plaques in patients with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Amyloid precursor-like protein 1 accumulates in neuritic plaques in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Bleomycin hydrolase immunoreactivity in senile plaque in the brains of patients with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Reelin in plaques of beta-amyloid precursor protein and presenilin-1 double-transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Neurons and plaques of Alzheimer's disease patients highly express the neuronal membrane docking protein p42IP4/centaurin alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Apolipoprotein B immunoreactivity in senile plaque and vascular amyloids and neurofibrillary tangles in the brains of patients with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Apolipoprotein D is a component of compact but not diffuse amyloid-beta plaques in Alzheimer's disease temporal cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Association of apolipoprotein J-positive beta-amyloid plaques with dystrophic neurites in Alzheimer's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

The SELDI-TOF MS approach to proteomics: protein profiling and biomarker identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

Alpha 1-antitrypsin and alpha 1-antichymotrypsin are in the lesions of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.4.2.227

21 January 2018

Identifiers

DOI

10.1586/14789450.4.2.227

1 reference

16 August 2017

1 reference