(Q36788347)

16 August 2017

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title

Cyclo-oxygenase-2 and its inhibition in cancer: is there a role? (English)

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16 August 2017

Zhongxing Liao

1

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16 August 2017

Kathryn A Mason

series ordinal

2

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16 August 2017

Luka Milas

series ordinal

3

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16 August 2017

1 January 2007

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16 August 2017

25

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inferred from page(s)

published in

Drugs

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16 August 2017

67

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16 August 2017

6

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16 August 2017

821-845

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https://scigraph.springernature.com/pub.10.2165/00003495-200767060-00001

16 August 2017

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cites work

The eicosanoids and their biochemical mechanisms of action

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200767060-00001

Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200767060-00001

Predisposition to colorectal cancer in rats with resolved colitis: role of cyclooxygenase-2-derived prostaglandin d2.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200767060-00001

Expression of cyclooxygenase-2 in human transitional cell carcinoma of the urinary bladder

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200767060-00001

Expression of cyclooxygenase 2 is an independent prognostic factor in human ovarian carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200767060-00001

Cyclooxygenase-2 expression in Helicobacter pylori-associated premalignant and malignant gastric lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200767060-00001

Enhanced expression of cyclooxygenase-2 in high grade human transitional cell bladder carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200767060-00001

Frequent co-localization of Cox-2 and laminin-5 gamma2 chain at the invasive front of early-stage lung adenocarcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200767060-00001

Specific inhibition of cyclooxygenase 2 restores antitumor reactivity by altering the balance of IL-10 and IL-12 synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200767060-00001

Modulation of signal-transduction pathways by chemopreventive agents

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200767060-00001

Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200767060-00001

Cyclooxygenase-2 (COX-2) enzyme inhibitors and radiotherapy: preclinical basis

21 January 2018

1 reference

12 December 2020

Proteomic profiling identifies cyclooxygenase-2-independent global proteomic changes by celecoxib in colorectal cancer cells.

1 reference

12 December 2020

Cyclooxygenase inhibitors--current status and future prospects

1 reference

12 December 2020

Cyclooxygenase-2 activity altered the cell-surface carbohydrate antigens on colon cancer cells and enhanced liver metastasis

1 reference

12 December 2020

Altered eicosanoid levels in human colon cancer

1 reference

12 December 2020

Effect of docetaxel on the therapeutic ratio of fractionated radiotherapy in vivo

1 reference

12 December 2020

The growth of malignant keratinocytes depends on signaling through the PGE(2) receptor EP1

1 reference

12 December 2020

Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial

1 reference

12 December 2020

The prostaglandin E2 receptor EP2 is required for cyclooxygenase 2-mediated mammary hyperplasia

1 reference

12 December 2020

Overexpression of cyclooxygenase-2 in gastric cancer correlates with the high abundance of vascular endothelial growth factor-C and lymphatic metastasis

1 reference

12 December 2020

Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs)

1 reference

12 December 2020

Association between cyclooxygenase-2-expressing macrophages, ulceration and microvessel density in colorectal cancer.

1 reference

12 December 2020

Cyclooxygenase-2 is up-regulated in proliferative inflammatory atrophy of the prostate, but not in prostate carcinoma.

1 reference

12 December 2020

Overexpression of cyclooxygenase-2 in nasopharyngeal carcinoma and association with epidermal growth factor receptor expression.

1 reference

12 December 2020

Potential involvement of IL-10 in suppressing tumor-associated macrophages. Colon-26-derived prostaglandin E2 inhibits TNF-alpha release via a mechanism involving IL-10.

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12 December 2020

Surgically induced accelerated local and distant tumor growth is significantly attenuated by selective COX-2 inhibition.

1 reference

12 December 2020

Cyclooxygenase-2 is overexpressed in HER-2/neu-positive breast cancer: evidence for involvement of AP-1 and PEA3.

1 reference

12 December 2020

Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study

1 reference

12 December 2020

Inhibitors of cyclo-oxygenase 2: a new class of anticancer agents?

1 reference

12 December 2020

Neoadjuvant selective COX-2 inhibition down-regulates important oncogenic pathways in patients with esophageal adenocarcinoma

1 reference

12 December 2020

In vitro enhancement of tumor cell radiosensitivity by a selective inhibitor of cyclooxygenase-2 enzyme: mechanistic considerations

1 reference

12 December 2020

The role of prostaglandins and other eicosanoids in the gastrointestinal tract

1 reference

12 December 2020

Expression of cyclooxygenase-1 and -2 in human colorectal cancer.

1 reference

12 December 2020

Cyclooxygenase-2 expression in human breast cancers and adjacent ductal carcinoma in situ.

1 reference

12 December 2020

Cyclooxygenase-2 inhibitor NS398 enhances antitumor effect of irradiation on hormone refractory human prostate carcinoma cells.

1 reference

12 December 2020

Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 AND p38 mitogen-activated protein kinase pathways

1 reference

12 December 2020

Cyclooxygenase mechanisms

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12 December 2020

High cyclooxygenase-2 expression following neoadjuvant radiochemotherapy is associated with minor histopathologic response and poor prognosis in esophageal cancer

1 reference

12 December 2020

Targeting the tumor vasculature with combretastatin A-4 disodium phosphate: effects on radiation therapy.

1 reference

12 December 2020

Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, and indomethacin against ultraviolet light-induced skin carcinogenesis.

1 reference

12 December 2020

Targeting angiogenic processes by combination rofecoxib and ionizing radiation

1 reference

12 December 2020

Prevention of colon cancer by low doses of celecoxib, a cyclooxygenase inhibitor, administered in diet rich in omega-3 polyunsaturated fatty acids

1 reference

12 December 2020

Prostaglandin endoperoxide synthase: why two isoforms?

1 reference

12 December 2020

Prognostic significance of cyclooxygenase 2 expression in 259 cases of non-small cell lung cancer.

1 reference

12 December 2020

Risk factors of colorectal cancer in inflammatory bowel disease.

1 reference

12 December 2020

Non-small cell lung cancer cycloxygenase activity and proliferation are inhibited by non-steroidal antiinflammatory drugs

1 reference

12 December 2020

The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes

1 reference

12 December 2020

Elevated cyclooxygenase-2 expression correlates with diminished survival in carcinoma of the cervix treated with radiotherapy

1 reference

12 December 2020

Host cyclooxygenase-2 modulates carcinoma growth.

1 reference

12 December 2020

Cycloxygenase-2 inhibition augments the efficacy of a cancer vaccine

1 reference

12 December 2020

COX-2 induction by heparanase in the progression of breast cancer.

1 reference

12 December 2020

Radiation induces upregulation of cyclooxygenase-2 (COX-2) protein in PC-3 cells

1 reference

12 December 2020

Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin.

1 reference

12 December 2020

15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma

1 reference

12 December 2020

Generation of mutagens during arachidonic acid metabolism

1 reference

12 December 2020

Prostaglandins and cancer

1 reference

12 December 2020

High cyclooxygenase-2 expression in stage IB cervical cancer with lymph node metastasis or parametrial invasion

1 reference

12 December 2020

Inhibition of murine natural killer cell activity by prostaglandins

1 reference

12 December 2020

Cyclooxygenase-2: molecular biology, pharmacology, and neurobiology

1 reference

12 December 2020

Correlation of aromatase and cyclooxygenase gene expression in human breast cancer specimens

1 reference

12 December 2020

Carcinogen substrate specificity of human COX-1 and COX-2.

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12 December 2020

Self-promotion? Intimate connections between APC and prostaglandin H synthase-2.

1 reference

12 December 2020

Expression and significance of cyclooxygenase 2 gene in lung cancer

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12 December 2020

Cyclooxygenase 2: a molecular target for cancer prevention and treatment

1 reference

12 December 2020

Aspirin use and the risk for colorectal cancer and adenoma in male health professionals

1 reference

12 December 2020

COX-2 overexpression increases motility and invasion of breast cancer cells.

1 reference

12 December 2020

Cyclooxygenase-2 expression in hepatocellular carcinoma

1 reference

12 December 2020

Inhibition of DNA repair as a mechanism of enhanced radioresponse of head and neck carcinoma cells by a selective cyclooxygenase-2 inhibitor, celecoxib

1 reference

12 December 2020

Role of reoxygenation in induction of enhancement of tumor radioresponse by paclitaxel.

1 reference

12 December 2020

Expression of cyclooxygenase-2 in human gastric adenomas and adenocarcinomas

1 reference

12 December 2020

Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas

1 reference

12 December 2020

Selective inhibitors of MEK1/ERK44/42 and p38 mitogen-activated protein kinases potentiate apoptosis induction by sulindac sulfide in human colon carcinoma cells.

1 reference

12 December 2020

Immunohistochemical analysis of cyclooxygenase-2 expression in pancreatic tumors

1 reference

12 December 2020

Prostaglandin production by murine tumors as a predictor for therapeutic response to indomethacin

1 reference

12 December 2020

Cyclooxygenase-2 expression in endometrial carcinoma: correlation with clinicopathologic parameters and clinical outcome

1 reference

12 December 2020

Celecoxib for the prevention of colorectal adenomatous polyps

1 reference

12 December 2020

Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer

1 reference

12 December 2020

Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdelta

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12 December 2020

Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer

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12 December 2020

Prostaglandin modulation of development of cell-mediated immunity in culture

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12 December 2020

Potential utility of COX-2 inhibitors in chemoprevention and chemotherapy

1 reference

12 December 2020

Disruption of cyclooxygenase-1 gene results in an impaired response to radiation injury.

1 reference

12 December 2020

Differential radioprotective effects of misoprostol in DNA repair-proficient and -deficient or radiosensitive cell systems

1 reference

12 December 2020

The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action.

1 reference

12 December 2020

The possible role of prostaglandins in mediating immune suppression by nonspecific T suppressor cells

1 reference

12 December 2020

Celecoxib for the prevention of sporadic colorectal adenomas

1 reference

12 December 2020

Cyclooxygenase-2 and epidermal growth factor receptor: pharmacologic targets for chemoprevention

1 reference

12 December 2020

Heparanase is involved in angiogenesis in esophageal cancer through induction of cyclooxygenase-2.

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12 December 2020

Targeting cyclooxygenase-2 in human neoplasia: rationale and promise

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12 December 2020

Combined therapy with weekly irinotecan, infusional 5-fluorouracil and the selective COX-2 inhibitor rofecoxib is a safe and effective second-line treatment in metastatic colorectal cancer

1 reference

12 December 2020

Celecoxib, a selective cyclo-oxygenase-2 inhibitor, enhances the response to preoperative paclitaxel and carboplatin in early-stage non-small-cell lung cancer

1 reference

12 December 2020

Differential effect of 9 beta-chloro-16, 16-dimethyl prostaglandin E2 (nocloprost) on the radiation response of human normal fibroblasts and colon adenocarcinoma cells

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12 December 2020

Celecoxib decreases Ki-67 proliferative index in active smokers

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12 December 2020

Preferential enhancement of tumor radioresponse by a cyclooxygenase-2 inhibitor

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12 December 2020

COX-2 inhibitors suppress integrin alpha5 expression in human lung carcinoma cells through activation of Erk: involvement of Sp1 and AP-1 sites

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12 December 2020

Increased expression of cyclooxygenase-2 in human pancreatic neoplasms and potential for chemoprevention by cyclooxygenase inhibitors

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12 December 2020

Polymorphism in the nuclear factor kappa-B binding promoter region of cyclooxygenase-2 is associated with an increased risk of bladder cancer.

1 reference

12 December 2020

Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer

1 reference

12 December 2020

The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis

1 reference

12 December 2020

Celecoxib inhibits prostate cancer growth: evidence of a cyclooxygenase-2-independent mechanism

1 reference

12 December 2020

Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer

1 reference

12 December 2020

Gemcitabine plus celecoxib (GECO) in advanced pancreatic cancer: a phase II trial

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12 December 2020

Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo

1 reference

12 December 2020

Molecular determinants of cetuximab efficacy

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12 December 2020

COX-2 inhibition and thrombotic tendency: a need for surveillance

1 reference

12 December 2020

Potentiation of cytotoxic therapies by TNP-470 and minocycline in mice bearing EMT-6 mammary carcinoma

1 reference

12 December 2020

Peroxisome proliferator-activated receptors: a nuclear receptor signaling pathway in lipid physiology

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12 December 2020

Aspirin use and lung, colon, and breast cancer incidence in a prospective study

1 reference

12 December 2020

Coexpression of cyclooxygenase-2 and thymidine phosphorylase as a prognostic indicator in patients with FIGO stage IIB squamous cell carcinoma of uterine cervix treated with radiotherapy and concurrent chemotherapy.

1 reference

12 December 2020

In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody

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12 December 2020

Chemotherapy induces the expression of cyclooxygenase-2 in non-small cell lung cancer

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12 December 2020

Cyclo-oxygenase inhibition reduces tumour growth and metastasis in an orthotopic model of breast cancer

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12 December 2020

Expression of cyclooxygenase-2 in prostate adenocarcinoma and benign prostatic hyperplasia

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12 December 2020

Coexpression of cyclooxygenases (COX-1, COX-2) and vascular endothelial growth factors (VEGF-A, VEGF-C) in esophageal adenocarcinoma

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12 December 2020

Growth stimulation of COX-2-negative pancreatic cancer by a selective COX-2 inhibitor.

1 reference

12 December 2020

Increase in radioresponse of murine tumors by treatment with indomethacin

1 reference

12 December 2020

Association of cyclooxygenase-2 and matrix metalloproteinase-2 expression in human breast cancer

1 reference

12 December 2020

Multitarget inhibition of drug-resistant multiple myeloma cell lines by dimethyl-celecoxib (DMC), a non-COX-2 inhibitory analog of celecoxib

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12 December 2020

Autocrine effects of fibroblast growth factor in repair of radiation damage in endothelial cells.

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12 December 2020

Early expression of cyclo-oxygenase-2 during sporadic colorectal carcinogenesis.

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12 December 2020

Clinical implications of expression of cyclooxygenase-2 related to angiogenesis in uterine endometrial cancers

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12 December 2020

Expression of inflammatory modulator COX-2 in pancreatic ductal adenocarcinoma and its relationship to pathologic and clinical parameters

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12 December 2020

Selective cyclooxygenase (COX)-1 or COX-2 inhibitors control metastatic disease in a murine model of breast cancer.

1 reference

12 December 2020

Potentiation of tumor response to radiation or chemoradiation by selective cyclooxygenase-2 enzyme inhibitors

1 reference

12 December 2020

Cisplatin, fluorouracil, celecoxib, and RT in resectable esophageal cancer: preliminary results.

1 reference

12 December 2020

Cyclooxygenase inhibitors suppress aromatase expression and activity in breast cancer cells.

1 reference

12 December 2020

G proteins: transducers of receptor-generated signals

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12 December 2020

Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation

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12 December 2020

Topical or systemic 16, 16 dm prostaglandin E2 or WR-2721 (WR-1065) protects mice from alopecia after fractionated irradiation

1 reference

12 December 2020

PGE2 and angiogenesis

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12 December 2020

Cyclooxygenase-2 overexpression enhances lymphatic invasion and metastasis in human gastric carcinoma

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12 December 2020

Cyclooxygenase-2 expression associated with severity of PanIN lesions: a possible link between chronic pancreatitis and pancreatic cancer.

1 reference

12 December 2020

Meloxicam inhibits the growth of non-small cell lung cancer

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12 December 2020

Cyclooxygenase-2 expression and prostaglandin E(2) synthesis are up-regulated in carcinomas of the cervix: a possible autocrine/paracrine regulation of neoplastic cell function via EP2/EP4 receptors

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12 December 2020

Regulation of MDR-1 (P-glycoprotein) by cyclooxygenase-2

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12 December 2020

Intratumoral COX-2 gene expression is a predictive factor for colorectal cancer response to fluoropyrimidine-based chemotherapy

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12 December 2020

Dependence of indomethacin-induced potentiation of murine tumor radioresponse on tumor host immunocompetence

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12 December 2020

Expression of cyclooxygenase 2 in human malignant melanoma.

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12 December 2020

Cyclooxygenase-2 is an independent prognostic factor in gastric cancer and its expression is regulated by the messenger RNA stability factor HuR.

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12 December 2020

Radiation response modification following molecular inhibition of epidermal growth factor receptor signaling

1 reference

12 December 2020

Targeting cyclooxygenase-2 in recurrent non-small cell lung cancer: a phase II trial of celecoxib and docetaxel

1 reference

12 December 2020

16, 16-dimethyl prostaglandin E2 increases survival of murine intestinal stem cells when given before photon radiation

1 reference

12 December 2020

Cyclooxygenase-2 expression in human colorectal cancer is unrelated to overall patient survival

1 reference

12 December 2020

Significant growth inhibition of human lung cancer cells both in vitro and in vivo by the combined use of a selective cyclooxygenase 2 inhibitor, JTE-522, and conventional anticancer agents.

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12 December 2020

Role of prostaglandin E1 and copper in angiogenesis

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12 December 2020

Inhibition of human neuroblastoma cell growth by CAY10404, a highly selective Cox-2 inhibitor.

1 reference

12 December 2020

COX-2, c-KIT and HER-2/neu expression in uterine carcinosarcomas: prognostic factors or potential markers for targeted therapies?

1 reference

12 December 2020

Selective inhibition of cyclooxygenase-2 inhibits colon cancer cell adhesion to extracellular matrix by decreased expression of beta1 integrin.

1 reference

12 December 2020

Survival time after surgery is inversely related to the amounts of prostaglandins extracted from human breast cancers [proceedings]

1 reference

12 December 2020

Cyclooxygenase-2 (COX-2), aromatase and breast cancer: a possible role for COX-2 inhibitors in breast cancer chemoprevention

1 reference

12 December 2020

Chemoprevention of breast cancer in rats by celecoxib, a cyclooxygenase 2 inhibitor

1 reference

12 December 2020

Selective cyclo-oxygenase-2 inhibitors and myocardial infarction: how strong is the link?

1 reference

12 December 2020

A selective cyclooxygenase-2 inhibitor, NS-398, enhances the effect of radiation in vitro and in vivo preferentially on the cells that express cyclooxygenase-2.

1 reference

12 December 2020

Do altering in ornithine decarboxylase activity and gene expression contribute to antiproliferative properties of COX inhibitors?

1 reference

12 December 2020

Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)

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12 December 2020

Multi-faceted analyses of a highly metastatic human lung cancer cell line NCI-H460-LNM35 suggest mimicry of inflammatory cells in metastasis.

1 reference

12 December 2020

Cyclo-oxygenase-2 enhances basic fibroblast growth factor-induced angiogenesis through induction of vascular endothelial growth factor in rat sponge implants

1 reference

12 December 2020

Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2

1 reference

12 December 2020

Cyclooxygenase-2 expression in normal ovaries and epithelial ovarian neoplasms

1 reference

12 December 2020

In vivo and in vitro radioprotective effects of the prostaglandin E1 analogue misoprostol in DNA repair-proficient and -deficient rodent cell systems

1 reference

12 December 2020

Aspirin use and risk of fatal cancer

1 reference

12 December 2020

Chemotherapeutic evaluation of Celecoxib, a cyclooxygenase-2 inhibitor, in a rat mammary tumor model

1 reference

12 December 2020

Risk of cardiovascular events associated with selective COX-2 inhibitors

1 reference

12 December 2020

Expression of cyclooxygenase-1 and cyclooxygenase-2 in bronchial epithelium and nonsmall cell lung carcinoma

1 reference

12 December 2020

Improvement strategies for molecular targeting: Cyclooxygenase-2 inhibitors as radiosensitizers for non-small cell lung cancer

1 reference

12 December 2020

Tumor growth inhibition by simultaneously blocking epidermal growth factor receptor and cyclooxygenase-2 in a xenograft model

1 reference

12 December 2020

COX-2 and its inhibition as a molecular target in the prevention and treatment of lung cancer

1 reference

12 December 2020

Up-regulation of cyclooxygenase 2 gene expression correlates with tumor angiogenesis in human colorectal cancer

1 reference

12 December 2020

Activation of matrix metalloproteinase-2 in human breast cancer cells overexpressing cyclooxygenase-1 or -2.

1 reference

12 December 2020

A phase I clinical trial of thoracic radiotherapy and concurrent celecoxib for patients with unfavorable performance status inoperable/unresectable non-small cell lung cancer

1 reference

12 December 2020

The relationship between cyclooxygenase-2 expression and colorectal cancer.

1 reference

12 December 2020

Cyclooxygenase-independent down-regulation of multidrug resistance-associated protein-1 expression by celecoxib in human lung cancer cells

1 reference

12 December 2020

The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis

1 reference

12 December 2020

Prostaglandin E2 activates mitogen-activated protein kinase/Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner.

1 reference

12 December 2020

Cyclooxygenase-2: a novel target for cancer chemotherapy?

1 reference

12 December 2020

Expression of cyclooxygenase-2 in human lung carcinoma

1 reference

12 December 2020

Prognostic role of cyclooxygenase-2 expression in esophageal carcinoma.

1 reference

12 December 2020

NS 398 radiosensitizes an HNSCC cell line by possibly inhibiting radiation-induced expression of COX-2.

1 reference

12 December 2020

COX-2 is expressed in human pulmonary, colonic, and mammary tumors.

1 reference

12 December 2020

The role of COX-2 inhibition in breast cancer treatment and prevention

1 reference

12 December 2020

Prognostic significance of elevated cyclooxygenase 2 expression in patients with adenocarcinoma of the esophagus

1 reference

12 December 2020

Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice

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12 December 2020

Role of cyclooxygenase-2 in immunomodulation and prognosis of endometrial carcinoma

1 reference

12 December 2020

Prognostic significance of elevated cyclooxygenase-2 expression in breast cancer

1 reference

12 December 2020

Cyclooxygenase-2 expression is up-regulated in squamous cell carcinoma of the head and neck.

1 reference

12 December 2020

Cyclooxygenase-2, P-glycoprotein-170 and drug resistance; is chemoprevention against multidrug resistance possible?

1 reference

12 December 2020

Metronomic oral low-dose treosulfan chemotherapy combined with cyclooxygenase-2 inhibitor in pretreated advanced melanoma: a pilot study

1 reference

12 December 2020

Enhancement of tumor response to gamma-radiation by an inhibitor of cyclooxygenase-2 enzyme

1 reference

12 December 2020

Cyclooxygenase-2 is overexpressed in human cervical cancer.

1 reference

12 December 2020

Expression of cyclooxygenase-2 in dysplasia of the stomach and in intestinal-type gastric adenocarcinoma.

1 reference

12 December 2020

Reciprocal paracrine interactions between tumour cells and endothelial cells: the 'angiogenesis progression' hypothesis

1 reference

12 December 2020

Phase II trial of irinotecan plus celecoxib in adults with recurrent malignant glioma

1 reference

12 December 2020

Cyclooxygenase-2 expression is up-regulated in transitional cell carcinoma and its preneoplastic lesions in the human urinary bladder

1 reference

12 December 2020

Celecoxib prevents tumor growth in vivo without toxicity to normal gut: lack of correlation between in vitro and in vivo models

1 reference

12 December 2020

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

1 reference

12 December 2020

Increased expression of inducible nitric oxide synthase and cyclooxygenase-2 in Barrett's esophagus and associated adenocarcinomas.

1 reference

12 December 2020

Celecoxib, a selective cyclooxygenase 2 inhibitor, protects against human epidermal growth factor receptor 2 (HER-2)/neu-induced breast cancer.

1 reference

12 December 2020

Xenobiotic metabolism by prostaglandin H synthase

1 reference

12 December 2020

Cyclooxygenase-2 (COX-2)-dependent and -independent anticarcinogenic effects of celecoxib in human colon carcinoma cells

1 reference

12 December 2020

Potential use of COX-2-aromatase inhibitor combinations in breast cancer

1 reference

12 December 2020

Immunohistochemical analysis and in situ hybridization of cyclooxygenase-2 expression in intraductal papillary-mucinous tumors of the pancreas

1 reference

12 December 2020

Cyclooxygenase-2 inhibition with celecoxib enhances antitumor efficacy and reduces diarrhea side effect of CPT-11.

1 reference

12 December 2020

Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors

1 reference

12 December 2020

Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: up-regulation of interleukin 10 and down-regulation of interleukin 12 production.

1 reference

12 December 2020

COX-2 and cancer: a new approach to an old problem

1 reference

12 December 2020

Chemoprevention of intestinal polyposis in the Apcdelta716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor

1 reference

12 December 2020

Interactions of natural effector cells and prostaglandins in the control of metastasis

1 reference

12 December 2020

Cyclooxygenase-2 expression in human esophageal carcinoma

1 reference

12 December 2020

Prognostic significance of elevated cyclooxygenase 2 expression in primary, resected lung adenocarcinomas

1 reference

12 December 2020

Combinatorial chemoprevention of intestinal neoplasia

1 reference

12 December 2020

Expression of cyclooxygenase-2 (COX-2) in hepatocellular carcinoma and growth inhibition of hepatoma cell lines by a COX-2 inhibitor, NS-398.

1 reference

12 December 2020

Chemopreventive effects of NSAIDs against colorectal cancer: regulation of apoptosis and mitosis by COX-1 and COX-2.

1 reference

12 December 2020

Correlation of cyclooxygenase-2 (COX-2) and aromatase expression in human endometrial cancer: tissue microarray analysis

1 reference

12 December 2020

Cyclooxygenase-2 expression: a significant prognostic indicator for patients with colorectal cancer.

1 reference

12 December 2020

Identification of functional genetic variants in cyclooxygenase-2 and their association with risk of esophageal cancer.

1 reference

12 December 2020

Expression of proteins related to prostaglandin E2 biosynthesis is increased in human gastric cancer and during gastric carcinogenesis.

1 reference

12 December 2020

Cyclooxygenase inhibitors modulate NK activities that control metastatic disease

1 reference

12 December 2020

Radiation protection against early and late effects of ionizing irradiation by the prostaglandin inhibitor indomethacin.

1 reference

12 December 2020

Enhancement of intrinsic tumor cell radiosensitivity induced by a selective cyclooxygenase-2 inhibitor

1 reference

12 December 2020

10.2165/00003495-200767060-00001

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DOI

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Dimensions Publication ID

16 August 2017

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