(Q36791851)

English

Amino acids are necessary for the insulin-induced activation of mTOR/S6K1 signaling and protein synthesis in healthy and insulin resistant human skeletal muscle

scientific article published on 14 March 2008

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18342407%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Amino acids are necessary for the insulin-induced activation of mTOR/S6K1 signaling and protein synthesis in healthy and insulin resistant human skeletal muscle (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18342407%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

insulin resistance

1 reference

based on heuristic

inferred from title

6

1 reference

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4 January 2020

Blake B. Rasmussen

7

1 reference

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4 January 2020

Micah J Drummond

1

object named as

Micah J Drummond

1 reference

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4 January 2020

5

object named as

Erin L Glynn

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4 January 2020

4

object named as

Hans C Dreyer

1 reference

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4 January 2020

author name string

Jill A Bell

2

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4 January 2020

Satoshi Fujita

3

1 reference

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4 January 2020

publication date

14 March 2008

1 reference

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4 January 2020

Clinical Nutrition

1 reference

Europe PubMed Central

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4 January 2020

27

1 reference

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4 January 2020

3

1 reference

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4 January 2020

447-456

1 reference

Europe PubMed Central

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4 January 2020

Nutrient signalling in the regulation of human muscle protein synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

The mTOR pathway in the control of protein synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

Dysregulation of muscle fatty acid metabolism in type 2 diabetes is independent of malonyl-CoA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

Effect of insulin on human skeletal muscle protein synthesis is modulated by insulin-induced changes in muscle blood flow and amino acid availability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

Skeletal muscle protein anabolic response to increased energy and insulin is preserved in poorly controlled type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

Signaling pathways and molecular mechanisms through which branched-chain amino acids mediate translational control of protein synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

Short-term insulin and nutritional energy provision do not stimulate muscle protein synthesis if blood amino acid availability decreases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

Oral leucine administration stimulates protein synthesis in rat skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

Serine 332 phosphorylation of insulin receptor substrate-1 by glycogen synthase kinase-3 attenuates insulin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

Invited Review: Role of insulin in translational control of protein synthesis in skeletal muscle by amino acids or exercise

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

Basal muscle amino acid kinetics and protein synthesis in healthy young and older men

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

Deficiency of dietary EAA preferentially inhibits mRNA translation of ribosomal proteins in liver of meal-fed rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. A negative feedback mechanism leading to insulin resistance in skeletal muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

Splanchnic glucose and amino acid metabolism in obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

Extreme hyperinsulinemia unmasks insulin's effect to stimulate protein synthesis in the human forearm.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

Bidirectional modulation of insulin action by amino acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

Effects of acute systemic hyperinsulinemia on forearm muscle proteolysis in healthy man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

29 September 2017

Amino acid- and lipid-induced insulin resistance in rat heart: molecular mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

27 June 2018

Effects of amino acids on glucose disposal.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

27 June 2018

Whole-body and tissue protein synthesis during brief and prolonged fasting in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

27 June 2018

Short-term regulation of insulin-mediated glucose utilization in four-day fasted human volunteers: role of amino acid availability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

27 June 2018

The Rab GTPase-activating protein AS160 integrates Akt, protein kinase C, and AMP-activated protein kinase signals regulating GLUT4 traffic.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

5 September 2018

Overactivation of S6 kinase 1 as a cause of human insulin resistance during increased amino acid availability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

5 September 2018

Differential regulation of protein dynamics in splanchnic and skeletal muscle beds by insulin and amino acids in healthy human subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

5 September 2018

Regulation of translation initiation by insulin and amino acids in skeletal muscle of neonatal pigs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

5 September 2018

Mechanism of amino acid-induced skeletal muscle insulin resistance in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

5 September 2018

Orally administered leucine stimulates protein synthesis in skeletal muscle of postabsorptive rats in association with increased eIF4F formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

5 September 2018

The disease burden associated with overweight and obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

5 September 2018

Insulin action on muscle protein kinetics and amino acid transport during recovery after resistance exercise.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

5 September 2018

Effects of flooding amino acids on incorporation of labeled amino acids into human muscle protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

5 September 2018

Protein and fat effects on glucose responses and insulin requirements in subjects with insulin-dependent diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

5 September 2018

Plasma Amino Acid Levels and Insulin Secretion in Obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2484120

5 September 2018

The effect of leucine infusion on substrate flux across the human forearm

1 reference

https://pubmed.ncbi.nlm.nih.gov/18342407

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperaminoacidaemia reduces insulin-mediated glucose disposal in healthy man

1 reference

https://pubmed.ncbi.nlm.nih.gov/18342407

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

alpha-Ketoisocaproate is superior to leucine in sparing glucose utilization in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/18342407

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased uptake of glucose by human forearm during infusion of leucine, isoleucine, or threonine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18342407

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of euglycemic hyperinsulinemia and amino acid infusion on regional and whole body glucose disposal in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/18342407

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of infused amino acids on glucose production and utilization in healthy human subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/18342407

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Obesity and insulin resistance: is it due to body fat, energy balance, or gut factors?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18342407

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.CLNU.2008.01.012

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18342407%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18342407%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18342407%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

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