(Q36798771)

16 August 2017

Constitutive activation of the N-methyl-D-aspartate receptor via cleft-spanning disulfide bonds (English)

1 reference

16 August 2017

Marie L Blanke

1

1 reference

16 August 2017

Antonius M J VanDongen

series ordinal

2

1 reference

16 August 2017

language of work or name

English

0 references

publication date

1 May 2008

1 reference

Journal of Biological Chemistry

16 August 2017

1 reference

16 August 2017

283

1 reference

16 August 2017

31

1 reference

16 August 2017

21519-21529

1 reference

Interdomain interactions in AMPA and kainate receptors regulate affinity for glutamate.

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Subunit arrangement and function in NMDA receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Mechanism of partial agonism at NMDA receptors for a conformationally restricted glutamate analog.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Mechanism of partial agonist action at the NR1 subunit of NMDA receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

AMPA receptor binding cleft mutations that alter affinity, efficacy, and recovery from desensitization.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Crystal structures of the GluR5 and GluR6 ligand binding cores: molecular mechanisms underlying kainate receptor selectivity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Structural features of the glutamate binding site in recombinant NR1/NR2A N-methyl-D-aspartate receptors determined by site-directed mutagenesis and molecular modeling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Subunit-specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Protons trap NR1/NR2B NMDA receptors in a nonconducting state.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Locking the dimeric GABA(B) G-protein-coupled receptor in its active state.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Structural basis for partial agonist action at ionotropic glutamate receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Studies of NMDA receptor function and stoichiometry with truncated and tandem subunits.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Molecular dynamics simulations of the ligand-binding domain of the ionotropic glutamate receptor GluR2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Intersubunit cooperativity in the NMDA receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

The dissociation of acetylcholine from open nicotinic receptor channels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Allosteric interaction between the amino terminal domain and the ligand binding domain of NR2A.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Molecular determinants of coordinated proton and zinc inhibition of N-methyl-D-aspartate NR1/NR2A receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Structure of a glutamate-receptor ligand-binding core in complex with kainate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Changing subunit composition of heteromeric NMDA receptors during development of rat cortex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Structural conservation of ion conduction pathways in K channels and glutamate receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

NMDA receptor-dependent excitotoxicity: the role of intracellular Ca2+ release

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Glycine decreases desensitization of N-methyl-D-aspartate (NMDA) receptors expressed in Xenopus oocytes and is required for NMDA responses.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Disruption of interdomain interactions in the glutamate binding pocket affects differentially agonist affinity and efficacy of N-methyl-D-aspartate receptor activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Synaptic NMDA receptor channels have a low open probability.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

NMDA application potentiates synaptic transmission in the hippocampus

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

A kinetic analysis of the modulation of N-methyl-D-aspartic acid receptors by glycine in mouse cultured hippocampal neurones

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Apparent desensitization of NMDA responses in xenopus oocytes involves calcium-dependent chloride current

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Decreased phosphorylation of NMDA receptor type 1 at serine 897 in brains of patients with Schizophrenia.

27 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709190200

D-cycloserine improves functional recovery and reinstates long-term potentiation (LTP) in a mouse model of closed head injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709190200

Molecular dynamics simulations of the ligand-binding domain of an N-methyl-D-aspartate receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709190200

The 5'-untranslated region of the N-methyl-D-aspartate receptor NR2A subunit controls efficiency of translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709190200

Molecular organization of a zinc binding n-terminal modulatory domain in a NMDA receptor subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709190200

Ligand-binding residues integrate affinity and efficacy in the NMDA receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709190200

Molecular determinants of proton-sensitive N-methyl-D-aspartate receptor gating.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709190200

Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709190200

Structural mobility of the extracellular ligand-binding core of an ionotropic glutamate receptor. Analysis of NMR relaxation dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709190200

Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709190200

Tweaking agonist efficacy at N-methyl-D-aspartate receptors by site-directed mutagenesis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

The NMDA receptor M3 segment is a conserved transduction element coupling ligand binding to channel opening.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Improved cognition in Alzheimer's disease with short-term D-cycloserine treatment.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Potentiation of NMDA receptor-mediated responses by dynorphin at low extracellular glycine concentrations

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490796

Long-term potentiation of NMDA receptor-mediated synaptic transmission in the hippocampus

5 September 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709190200

In silico mutation of cysteine residues in the ligand-binding domain of an N-methyl-D-aspartate receptor

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18450751

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M709190200

1 reference

16 August 2017

1 reference

16 August 2017

PubMed publication ID

18450751

1 reference