(Q36799967)

English

Release of Active Peptidyl Arginine Deiminases by Neutrophils Can Explain Production of Extracellular Citrullinated Autoantigens in Rheumatoid Arthritis Synovial Fluid

scientific article published on 5 August 2015

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scholarly article

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21 February 2020

Release of Active Peptidyl Arginine Deiminases by Neutrophils Can Explain Production of Extracellular Citrullinated Autoantigens in Rheumatoid Arthritis Synovial Fluid (English)

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21 February 2020

rheumatoid arthritis

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Jimmy Ytterberg

3

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21 February 2020

4

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21 February 2020

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21 February 2020

Melissa M. Grant

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21 February 2020

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21 February 2020

Christopher D Buckley

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Christopher D Buckley

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21 February 2020

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Julia Spengler

1

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21 February 2020

Božo Lugonja

2

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21 February 2020

Andrew J Creese

5

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21 February 2020

Michael Milward

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21 February 2020

Karin Lundberg

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21 February 2020

Andrew Filer

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21 February 2020

Karim Raza

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21 February 2020

Iain L Chapple

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21 February 2020

Dagmar Scheel-Toellner

15

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21 February 2020

publication date

1 December 2015

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21 February 2020

Arthritis & Rheumatology

1 reference

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21 February 2020

67

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21 February 2020

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21 February 2020

3135-3145

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21 February 2020

Demonstration of extracellular peptidylarginine deiminase (PAD) activity in synovial fluid of patients with rheumatoid arthritis using a novel assay for citrullination of fibrinogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

The multifactorial role of neutrophils in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Features of the synovium of individuals at risk of developing rheumatoid arthritis: implications for understanding preclinical rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Immune-mediated pore-forming pathways induce cellular hypercitrullination and generate citrullinated autoantigens in rheumatoid arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Antibodies from patients with rheumatoid arthritis target citrullinated histone 4 contained in neutrophils extracellular traps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Erosive rheumatoid arthritis is associated with antibodies that activate PAD4 by increasing calcium sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

In silico instrumental response correction improves precision of label-free proteomics and accuracy of proteomics-based predictive models.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

The expanding world of extracellular traps: not only neutrophils but much more

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

PAD4 is not essential for disease in the K/BxN murine autoantibody-mediated model of arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Neutrophil extracellular trap formation is associated with IL-1β and autophagy-related signaling in gout

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Neutrophil elastase enhances sputum solubilization in cystic fibrosis patients receiving DNase therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Felty's syndrome autoantibodies bind to deiminated histones and neutrophil extracellular chromatin traps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: novel insights into autoantigen selection in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Peculiarities of cell death mechanisms in neutrophils.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

The value of ultrasonography in predicting arthritis in auto-antibody positive arthralgia patients: a prospective cohort study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Neutrophil fate in gingival crevicular fluid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Neutrophil extracellular traps contain calprotectin, a cytosolic protein complex involved in host defense against Candida albicans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Dying and necrotic neutrophils are anti-inflammatory secondary to the release of alpha-defensins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Immunity to citrullinated proteins in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Synovial fluid leukocyte apoptosis is inhibited in patients with very early rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Hypothesis: the humoral immune response to oral bacteria provides a stimulus for the development of rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Structural basis for Ca(2+)-induced activation of human PAD4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Neutrophil extracellular traps kill bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Nuclear localization of peptidylarginine deiminase V and histone deimination in granulocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Disease distribution of synovial fluid mast cells and cytophagocytic mononuclear cells in inflammatory arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

29 September 2017

Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

27 June 2018

The presence of citrullinated proteins is not specific for rheumatoid synovial tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

27 June 2018

Expression and activity of citrullinating peptidylarginine deiminase enzymes in monocytes and macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

27 June 2018

Metabolic comparison between basophils and other leukocytes from human blood.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

27 June 2018

Assessing the citrullinome in rheumatoid arthritis synovial fluid with and without enrichment of citrullinated peptides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

5 September 2018

Structural changes and antibody enrichment in the lungs are early features of anti-citrullinated protein antibody-positive rheumatoid arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

5 September 2018

Ultrasound-guided synovial biopsy: a safe, well-tolerated and reliable technique for obtaining high-quality synovial tissue from both large and small joints in early arthritis patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

5 September 2018

Synovial fluid is a site of citrullination of autoantigens in inflammatory arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

5 September 2018

Peptidyl arginine deiminase type 2 (PAD-2) and PAD-4 but not PAD-1, PAD-3, and PAD-6 are expressed in rheumatoid arthritis synovium in close association with tissue inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

5 September 2018

Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

5 September 2018

Synovial intracellular citrullinated proteins colocalizing with peptidyl arginine deiminase as pathophysiologically relevant antigenic determinants of rheumatoid arthritis-specific humoral autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

5 September 2018

The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4832324

5 September 2018

Detection of citrulline residues in deiminated proteins on polyvinylidene difluoride membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/26245941

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The rheumatoid arthritis synovial fluid citrullinome reveals novel citrullinated epitopes in apolipoprotein E, myeloid nuclear differentiation antigen, and β-actin

1 reference

https://pubmed.ncbi.nlm.nih.gov/26245941

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ABAP: antibody-based assay for peptidylarginine deiminase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/26245941

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Psoriatic arthritis (PSA)--an analysis of 220 patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/26245941

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cytology of joint exudates in rheumatoid arthritis. Morphology and preparation techniques

1 reference

https://pubmed.ncbi.nlm.nih.gov/26245941

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dna in synovial fluid and the circulation of patients with arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/26245941

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different stages of rheumatoid arthritis: features of the synovium in the preclinical phase

1 reference

https://pubmed.ncbi.nlm.nih.gov/26245941

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/ART.39313

1 reference

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21 February 2020

PMC publication ID

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Europe PubMed Central

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21 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26245941%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

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