(Q36800989)

16 August 2017

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title

Rethinking peptide supply to MHC class I molecules (English)

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16 August 2017

Laurence C Eisenlohr

1

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PubMed ID

17457346

16 August 2017

Lan Huang

series ordinal

2

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PubMed ID

17457346

16 August 2017

Tania N Golovina

series ordinal

3

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16 August 2017

1 May 2007

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Nature Reviews Immunology

16 August 2017

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16 August 2017

7

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16 August 2017

403-410

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16 August 2017

5

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Increased degradation rates of protein synthesized in hepatoma cells in the presence of amino acid analogues

16 August 2017

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Quantifying the contribution of defective ribosomal products to antigen production: a model-based computational analysis

21 January 2018

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Molecular chaperones in protein quality control

21 January 2018

1 reference

The impact of misfolding versus targeted degradation on the efficiency of the MHC class I-restricted antigen processing.

21 January 2018

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An evaluation of enforced rapid proteasomal degradation as a means of enhancing vaccine-induced CTL responses

21 January 2018

1 reference

Tight linkage between translation and MHC class I peptide ligand generation implies specialized antigen processing for defective ribosomal products

21 January 2018

1 reference

Intracellular localization of proteasomal degradation of a viral antigen

21 January 2018

1 reference

Toward a definition of self: proteomic evaluation of the class I peptide repertoire

21 January 2018

1 reference

Mechanisms of MHC class I-restricted antigen processing and cross-presentation

21 January 2018

1 reference

Processing and presentation of tumor antigens and vaccination strategies

31 March 2020

1 reference

CD8+ T cell cross-priming via transfer of proteasome substrates

31 March 2020

1 reference

Cross-priming utilizes antigen not available to the direct presentation pathway.

31 March 2020

1 reference

Biosynthesis of Hemoglobin Ann Arbor: Evidence for Catabolic and Feedback Regulation

31 March 2020

1 reference

Rapid postsynthetic destruction of unstable haemoglobin Bushwick

31 March 2020

1 reference

Degradation of abnormal proteins in Escherichia coli (protein breakdown-protein structure-mistranslation-amino acid analogs-puromycin).

31 March 2020

1 reference

Degradation of abnormal proteins in Escherichia coli: relative susceptibility of canavanyl proteins and puromycin peptides to proteolysis in vitro

31 March 2020

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Kinetics of degradation of "short-" and "long-lived" proteins in cultured mammalian cells.

31 March 2020

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Rapid degradation of a large fraction of newly synthesized proteins by proteasomes.

31 March 2020

1 reference

Protein synthesis upon acute nutrient restriction relies on proteasome function

31 March 2020

1 reference

The DRiP hypothesis decennial: support, controversy, refinement and extension

31 March 2020

1 reference

Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen.

31 March 2020

1 reference

31 March 2020

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The seven dirty little secrets of major histocompatibility complex class I antigen processing

31 March 2020

1 reference

The major substrates for TAP in vivo are derived from newly synthesized proteins

31 March 2020

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Quantitating protein synthesis, degradation, and endogenous antigen processing

31 March 2020

1 reference

Detecting and measuring cotranslational protein degradation in vivo

31 March 2020

1 reference

31 March 2020

1 reference

The fundamentals of protein folding: bringing together theory and experiment

31 March 2020

1 reference

Principles of protein folding in the cellular environment

31 March 2020

1 reference

Posttranslational quality control: folding, refolding, and degrading proteins.

31 March 2020

1 reference

Folding of newly translated proteins in vivo: the role of molecular chaperones

31 March 2020

1 reference

Protein folding, misfolding, and aggregation. Formation of inclusion bodies and aggresomes.

31 March 2020

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Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution

31 March 2020

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Cooperation of molecular chaperones with the ubiquitin/proteasome system

31 March 2020

1 reference

Some like it hot: the structure and function of small heat-shock proteins.

31 March 2020

1 reference

A cradle for new proteins: trigger factor at the ribosome

31 March 2020

1 reference

Molecular guardians for newborn proteins: ribosome-associated chaperones and their role in protein folding

31 March 2020

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A conserved motif is prerequisite for the interaction of NAC with ribosomal protein L23 and nascent chains

31 March 2020

1 reference

The chaperones MPP11 and Hsp70L1 form the mammalian ribosome-associated complex

31 March 2020

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The battle of the fold: chaperones take on prions

31 March 2020

1 reference

Relative activities and stabilities of mutant Escherichia coli tryptophan synthase alpha subunits

31 March 2020

1 reference

Characterization of novel cathepsin K mutations in the pro and mature polypeptide regions causing pycnodysostosis.

31 March 2020

1 reference

The functional consequences of mis-sense mutations affecting an intra-molecular salt bridge in arylsulphatase A.

31 March 2020

1 reference

Characterization of four variant forms of human propionyl-CoA carboxylase expressed in Escherichia coli

31 March 2020

1 reference

Protein folding revisited. A polypeptide chain at the folding ? misfolding ? nonfolding cross-roads: which way to go?

31 March 2020

1 reference

Degradation of CFTR by the ubiquitin-proteasome pathway

31 March 2020

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Most F508del-CFTR is targeted to degradation at an early folding checkpoint and independently of calnexin

31 March 2020

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Destabilization of the transmembrane domain induces misfolding in a phenotypic mutant of cystic fibrosis transmembrane conductance regulator

31 March 2020

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Intracellular localization of proteasomes

31 March 2020

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Molecular chaperones and protein quality control

31 March 2020

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Characterization of rapidly degraded polypeptides in mammalian cells reveals a novel layer of nascent protein quality control.

31 March 2020

1 reference

FAT10, a ubiquitin-independent signal for proteasomal degradation

31 March 2020

1 reference

20S proteasomal degradation of ornithine decarboxylase is regulated by NQO1

31 March 2020

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Association between HTLV-1 Tax and I kappa B alpha is dependent on the I kappa B alpha phosphorylation state

31 March 2020

1 reference

Ubiquitin-independent proteolytic functions of the proteasome

31 March 2020

1 reference

A degradation signal located in the C-terminus of p21WAF1/CIP1 is a binding site for the C8 alpha-subunit of the 20S proteasome

31 March 2020

1 reference

Binding and regulation of HIF-1alpha by a subunit of the proteasome complex, PSMA7

31 March 2020

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20S proteasome prevents aggregation of heat-denatured proteins without PA700 regulatory subcomplex like a molecular chaperone

31 March 2020

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Chaperone activities of the 26S and 20S proteasome

31 March 2020

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Hsp70 chaperone machines.

31 March 2020

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Three-state equilibrium of Escherichia coli trigger factor

31 March 2020

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Dissecting functional similarities of ribosome-associated chaperones from Saccharomyces cerevisiae and Escherichia coli.

31 March 2020

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Intracellular protein degradation: basis of a self-regulating mechanism for the proteolysis of endogenous proteins

31 March 2020

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Introduction of a glycosylation site into a secreted protein provides evidence for an alternative antigen processing pathway: transport of precursors of major histocompatibility complex class I-restricted peptides from the endoplasmic reticulum to t

31 March 2020

1 reference

The class I antigen-processing pathway for the membrane protein tyrosinase involves translation in the endoplasmic reticulum and processing in the cytosol

31 March 2020

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ERAD: the long road to destruction

31 March 2020

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Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload

31 March 2020

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Immune recognition of a human renal cancer antigen through post-translational protein splicing.

31 March 2020

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An antigenic peptide produced by peptide splicing in the proteasome

31 March 2020

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Self-inhibition of synthesis and antigen presentation by Epstein-Barr virus-encoded EBNA1.

31 March 2020

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Inhibition of antigen processing by the internal repeat region of the Epstein-Barr virus nuclear antigen-1.

31 March 2020

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In vivo half-life of a protein is a function of its amino-terminal residue

31 March 2020

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Mitosis: a matter of getting rid of the right protein at the right time

31 March 2020

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Characterization of endoplasmic reticulum-associated degradation of a protein S mutant identified in a family of quantitative protein S deficiency

31 March 2020

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Quality control of a mutant plasma membrane ATPase: ubiquitylation prevents cell-surface stability

31 March 2020

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A novel mouse Smad4 mutation reduces protein stability and wild-type protein levels

31 March 2020

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Trapping of normal EB1 ligands in aggresomes formed by an EB1 deletion mutant

31 March 2020

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The biological and chemical basis for tissue-selective amyloid disease

31 March 2020

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Variation in the biochemical/biophysical properties of mutant superoxide dismutase 1 enzymes and the rate of disease progression in familial amyotrophic lateral sclerosis kindreds.

31 March 2020

1 reference

Identification of a novel amino acid deletion mutation and a very rare single nucleotide variant in a Japanese family with type I antithrombin deficiency

31 March 2020

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Trafficking defects of a novel autosomal recessive distal renal tubular acidosis mutant (S773P) of the human kidney anion exchanger (kAE1).

31 March 2020

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Familial Parkinson's disease-associated L166P mutation disrupts DJ-1 protein folding and function

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRI2077

1 reference

16 August 2017

1 reference

PubMed ID

17457346