(Q36802373)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27001839%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

title

CRLX101 nanoparticles localize in human tumors and not in adjacent, nonneoplastic tissue after intravenous dosing (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27001839%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

0 references

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27001839%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

8

Mark E Davis

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27001839%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

2

Devin T Wiley

1 reference

30 March 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27001839%20AND%20SRC:MED&resulttype=core&format=json

Andrew J Clark

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27001839%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Jonathan E Zuckerman

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27001839%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Joseph Chao

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27001839%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

James Lin

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27001839%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Yun Yen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27001839%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

language of work or name

English

0 references

publication date

21 March 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27001839%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

30 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27001839%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

volume

113

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27001839%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

issue

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27001839%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

page(s)

3850-3854

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27001839%20AND%20SRC:MED&resulttype=core&format=json

Biological and therapeutic impact of intratumor heterogeneity in cancer evolution

30 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4833237

Toward a full understanding of the EPR effect in primary and metastatic tumors as well as issues related to its heterogeneity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4833237

Correlating preclinical animal studies and human clinical trials of a multifunctional, polymeric nanoparticle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4833237

Serial diffusion MRI to monitor and model treatment response of the targeted nanotherapy CRLX101

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4833237

First-in-human phase 1/2a trial of CRLX101, a cyclodextrin-containing polymer-camptothecin nanopharmaceutical in patients with advanced solid tumor malignancies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4833237

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4833237

Proteasome-dependent processing of topoisomerase I-DNA adducts into DNA double strand breaks at arrested replication forks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4833237

Pharmacokinetics and tumor dynamics of the nanoparticle IT-101 from PET imaging and tumor histological measurements

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4833237

Transcriptional control of the tumor- and hypoxia-marker carbonic anhydrase 9: A one transcription factor (HIF-1) show?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4833237

Nanoparticle therapeutics: an emerging treatment modality for cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4833237

Cullin 3 promotes proteasomal degradation of the topoisomerase I-DNA covalent complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4833237

Synthesis of linear, beta-cyclodextrin-based polymers and their camptothecin conjugates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4833237

Transcription-dependent degradation of topoisomerase I-DNA covalent complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4833237

Effective targeting of solid tumors in patients with locally advanced cancers by radiolabeled pegylated liposomes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4833237

Degradation of topoisomerase I induced by topoisomerase I inhibitors is dependent on inhibitor structure but independent of cell death

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4833237

Translational impact of nanoparticle-drug conjugate CRLX101 with or without bevacizumab in advanced ovarian cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4833237

Pharmacodynamic and pharmacogenomic study of the nanoparticle conjugate of camptothecin CRLX101 for the treatment of cancer

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4833237

Microvessel count predicts metastasis and prognosis in patients with gastric cancer

5 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27001839

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Ubiquitin-dependent destruction of topoisomerase I is stimulated by the antitumor drug camptothecin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27001839

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Liposomal doxorubicin and conventionally fractionated radiotherapy in the treatment of locally advanced non-small-cell lung cancer and head and neck cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27001839

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1603018113

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27001839%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27001839%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

PubMed publication ID

27001839

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27001839%20AND%20SRC:MED&resulttype=core&format=json