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The antimalarial trioxaquine DU1301 alkylates heme in malaria-infected mice.
scientific article published on 16 June 2008
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
2493093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18559651%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
title
The antimalarial trioxaquine DU1301 alkylates heme in malaria-infected mice
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2493093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18559651%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
main subject
malaria
0 references
antimalarial
0 references
author
Fatima Bousejra-El Garah
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2493093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18559651%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
Bernard Meunier
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
2493093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18559651%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
Anne Robert
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
2493093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18559651%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
Françoise Benoit-Vical
object named as
Françoise Benoit-Vical
series ordinal
3
0 references
author name string
Catherine Claparols
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2493093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18559651%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
language of work or name
English
0 references
publication date
16 June 2008
1 reference
stated in
Europe PubMed Central
PMC publication ID
2493093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18559651%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
published in
Antimicrobial Agents and Chemotherapy
1 reference
stated in
Europe PubMed Central
PMC publication ID
2493093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18559651%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
volume
52
1 reference
stated in
Europe PubMed Central
PMC publication ID
2493093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18559651%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
issue
8
1 reference
stated in
Europe PubMed Central
PMC publication ID
2493093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18559651%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
page(s)
2966-2969
1 reference
stated in
Europe PubMed Central
PMC publication ID
2493093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18559651%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
cites work
Qinghaosu (Artemisinin): The Price of Success
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2493093
retrieved
29 September 2017
Hybrid molecules with a dual mode of action: dream or reality?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2493093
retrieved
29 September 2017
New developments in synthetic peroxidic drugs as artemisinin mimics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2493093
retrieved
29 September 2017
Trioxaquines are new antimalarial agents active on all erythrocytic forms, including gametocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2493093
retrieved
29 September 2017
The antimalarial drug artemisinin alkylates heme in infected mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2493093
retrieved
29 September 2017
Synthetic peroxides as antimalarials
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2493093
retrieved
29 September 2017
A medicinal chemistry perspective on artemisinin and related endoperoxides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2493093
retrieved
29 September 2017
Epidemiology of drug-resistant malaria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2493093
retrieved
29 September 2017
On the molecular mechanism of chloroquine's antimalarial action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2493093
retrieved
29 September 2017
Reaction of antimalarial endoperoxides with specific parasite proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2493093
retrieved
29 September 2017
Trioxaquines and heme-artemisinin adducts inhibit the in vitro formation of hemozoin better than chloroquine.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2493093
retrieved
27 June 2018
Cellular uptake of chloroquine is dependent on binding to ferriprotoporphyrin IX and is independent of NHE activity in Plasmodium falciparum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2493093
retrieved
27 June 2018
A nuclear magnetic resonance study of the interactions of antimalarial drugs with porphyrins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2493093
retrieved
27 June 2018
The chemotherapy of rodent malaria, XXII. The value of drug-resistant strains of P. berghei in screening for blood schizontocidal activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2493093
retrieved
27 June 2018
Dispiro-1,2,4-trioxane analogues of a prototype dispiro-1,2,4-trioxolane: mechanistic comparators for artemisinin in the context of reaction pathways with iron(II).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2493093
retrieved
5 September 2018
Heme alkylation by artesunic acid and trioxaquine DU1301, two antimalarial trioxanes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2493093
retrieved
5 September 2018
Synthesis and antimalarial activity of trioxaquine derivatives
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2493093
retrieved
5 September 2018
Recrudescence in artesunate-treated patients with falciparum malaria is dependent on parasite burden not on parasite factors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2493093
retrieved
5 September 2018
The interaction of artemisinin with malarial hemozoin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2493093
retrieved
5 September 2018
Mechanism-based design, synthesis, and in vitro antimalarial testing of new 4-methylated trioxanes structurally related to artemisinin: the importance of a carbon-centered radical for antimalarial activity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18559651
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/AAC.00165-08
1 reference
stated in
Europe PubMed Central
PMC publication ID
2493093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18559651%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
PMC publication ID
2493093
1 reference
stated in
Europe PubMed Central
PMC publication ID
2493093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18559651%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
PubMed publication ID
18559651
1 reference
stated in
Europe PubMed Central
PMC publication ID
2493093
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18559651%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 January 2020
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