(Q36808739)

16 August 2017

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title

Polyspecific organic cation transporters: structure, function, physiological roles, and biopharmaceutical implications (English)

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16 August 2017

Hermann Koepsell

1

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PubMed ID

17473959

16 August 2017

Katrin Lips

series ordinal

2

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PubMed ID

17473959

16 August 2017

Christopher Volk

series ordinal

3

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16 August 2017

1 May 2007

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16 August 2017

Pharmaceutical Research

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16 August 2017

24

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16 August 2017

7

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16 August 2017

1227-1251

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Gene expression levels and immunolocalization of organic ion transporters in the human kidney.

16 August 2017

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12 December 2020

Two novel missense mutations of the OCTN2 gene (W283R and V446F) in a patient with primary systemic carnitine deficiency

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12 December 2020

Human neurons express the polyspecific cation transporter hOCT2, which translocates monoamine neurotransmitters, amantadine, and memantine

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12 December 2020

Tissue distribution and renal developmental changes in rat organic cation transporter mRNA levels

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12 December 2020

Identification and functional characterization of a new human kidney-specific H+/organic cation antiporter, kidney-specific multidrug and toxin extrusion 2.

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12 December 2020

Cloning and characterization of two human polyspecific organic cation transporters

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12 December 2020

Acetylcholine and molecular components of its synthesis and release machinery in the urothelium

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12 December 2020

Analysis of the influence of OCTN1/2 variants within the IBD5 locus on disease susceptibility and growth indices in early onset inflammatory bowel disease

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12 December 2020

Corticosterone-sensitive monoamine transport in the rat dorsomedial hypothalamus: potential role for organic cation transporter 3 in stress-induced modulation of monoaminergic neurotransmission.

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12 December 2020

Characterization of the organic cation transporter SLC22A16: a doxorubicin importer

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12 December 2020

Membrane localization of the electrogenic cation transporter rOCT1 in rat liver

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12 December 2020

Structure and mechanism of the lactose permease of Escherichia coli

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12 December 2020

Transport of monoamine transmitters by the organic cation transporter type 2, OCT2.

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12 December 2020

Tissue distribution and ontogeny of organic cation transporters in mice

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12 December 2020

Organic cation transporters are determinants of oxaliplatin cytotoxicity.

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12 December 2020

Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters

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12 December 2020

Association between tubular toxicity of cisplatin and expression of organic cation transporter rOCT2 (Slc22a2) in the rat.

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12 December 2020

Murine hematopoietic progenitors are capable of both histamine synthesis and uptake.

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12 December 2020

Novel single nucleotide polymorphisms of organic cation transporter 1 (SLC22A1) affecting transport functions

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12 December 2020

1-Methyl-4-phenylpyridinium accumulates in cerebellar granule neurons via organic cation transporter 3.

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12 December 2020

Involvement of organic cation transporter 1 in hepatic and intestinal distribution of metformin

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12 December 2020

Gene-dose effect on carnitine transport activity in embryonic fibroblasts of JVS mice as a model of human carnitine transporter deficiency

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12 December 2020

Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2

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12 December 2020

Abnormal expression of urea cycle enzyme genes in juvenile visceral steatosis (jvs) mice

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12 December 2020

Screening of the interaction between xenobiotic transporters and PDZ proteins

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12 December 2020

Monoamine neurotransmitter transport mediated by the polyspecific cation transporter rOCT1.

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12 December 2020

Individual PKC-phosphorylation sites in organic cation transporter 1 determine substrate selectivity and transport regulation

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12 December 2020

A missense mutation of mouse OCTN2, a sodium-dependent carnitine cotransporter, in the juvenile visceral steatosis mouse.

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12 December 2020

Mutations in the organic cation/carnitine transporter OCTN2 in primary carnitine deficiency

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12 December 2020

Amino acids critical for substrate affinity of rat organic cation transporter 1 line the substrate binding region in a model derived from the tertiary structure of lactose permease

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12 December 2020

Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.

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12 December 2020

Mutations of OCTN2, an organic cation/carnitine transporter, lead to deficient cellular carnitine uptake in primary carnitine deficiency

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12 December 2020

Abnormal sodium stimulation of carnitine transport in primary carnitine deficiency

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12 December 2020

Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit altered function

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12 December 2020

Transcriptional regulation of murine Slc22a1 (Oct1) by peroxisome proliferator agonist receptor-alpha and -gamma

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12 December 2020

Down-regulation of rat organic cation transporter rOCT2 by 5/6 nephrectomy

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12 December 2020

Molecular cloning, functional characterization and genomic organization of four alternatively spliced isoforms of the human organic cation transporter 1 (hOCT1/SLC22A1)

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12 December 2020

The function of Gp170, the multidrug-resistance gene product, in the brush border of rat intestinal mucosa

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12 December 2020

Expression and functional characterization of the extraneuronal monoamine transporter in normal human astrocytes

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12 December 2020

Functional characteristics and steroid hormone-mediated regulation of an organic cation transporter in Madin-Darby canine kidney cells.

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12 December 2020

Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta

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12 December 2020

Cisplatin nephrotoxicity is critically mediated via the human organic cation transporter 2

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12 December 2020

Variants of OCTN1-2 cation transporter genes are associated with both Crohn's disease and ulcerative colitis

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12 December 2020

Variability in mRNA expression of ABC- and SLC-transporters in human intestinal cells: comparison between human segments and Caco-2 cells.

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12 December 2020

Involvement of OCTN1 (SLC22A4) in pH-dependent transport of organic cations.

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12 December 2020

Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli

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12 December 2020

Down-regulation of the organic cation transporter 1 of rat liver in obstructive cholestasis

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12 December 2020

A human transporter protein that mediates the final excretion step for toxic organic cations

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12 December 2020

Mechanism of electrogenic cation transport by the cloned organic cation transporter 2 from rat.

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12 December 2020

Transporter-mediated renal handling of nafamostat mesilate

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12 December 2020

Metformin therapy in polycystic ovary syndrome reduces hyperinsulinemia, insulin resistance, hyperandrogenemia, and systolic blood pressure, while facilitating normal menses and pregnancy

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12 December 2020

Primary structure and functional expression of the apical organic cation transporter from kidney epithelial LLC-PK1 cells.

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12 December 2020

Reduced tubular cation transport in diabetes: prevented by ACE inhibition

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12 December 2020

Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium

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12 December 2020

Sex differences in the mRNA, protein, and functional expression of organic anion transporter (Oat) 1, Oat3, and organic cation transporter (Oct) 2 in rabbit renal proximal tubules

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12 December 2020

Expression and distribution of OCTN2 in mouse epididymis and its association with obstructive azoospermia in juvenile visceral steatosis mice.

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12 December 2020

Molecular and cellular physiology of renal organic cation and anion transport

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12 December 2020

Decreased activity of basolateral organic ion transports in hyperuricemic rat kidney: roles of organic ion transporters, rOAT1, rOAT3 and rOCT2.

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12 December 2020

Specificity of transporters for 'organic anions' and 'organic cations' in the kidney

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12 December 2020

Cimetidine-procainamide pharmacokinetic interaction in man: Evidence of competition for tubular secretion of basic drugs

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12 December 2020

Absorption and secretion of monoquaternary ammonium compounds by the isolated intestinal mucosa

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12 December 2020

OCTNs: will the real IBD5 gene please stand up?

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12 December 2020

Novel OCTN2 mutations: no genotype-phenotype correlations: early carnitine therapy prevents cardiomyopathy.

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12 December 2020

Dysfunctions of the epididymis as a result of primary carnitine deficiency in juvenile visceral steatosis mice

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12 December 2020

Drug specificity and intestinal membrane localization of human organic cation transporters (OCT).

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12 December 2020

Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney

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12 December 2020

Organic cation transporters in intestine, kidney, liver, and brain

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12 December 2020

Down-regulation of the non-neuronal acetylcholine synthesis and release machinery in acute allergic airway inflammation of rat and mouse

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12 December 2020

Xenobiotic and endobiotic transporter mRNA expression in the blood-testis barrier

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12 December 2020

OCTN3: A Na+-independent L-carnitine transporter in enterocytes basolateral membrane

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12 December 2020

A conserved glutamate residue in transmembrane helix 10 influences substrate specificity of rabbit OCT2 (SLC22A2).

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12 December 2020

The human organic cation transporter-1 gene is transactivated by hepatocyte nuclear factor-4alpha

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12 December 2020

Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter

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12 December 2020

Localization of organic cation transporters OCT1 and OCT2 in rat kidney

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12 December 2020

Epitope shared by functional variant of organic cation/carnitine transporter, OCTN1, Campylobacter jejuni and Mycobacterium paratuberculosis may underlie susceptibility to Crohn's disease at 5q31.

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12 December 2020

Decreased function of genetic variants, Pro283Leu and Arg287Gly, in human organic cation transporter hOCT1

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12 December 2020

Cloning and characterization of a novel human pH-dependent organic cation transporter, OCTN1

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12 December 2020

Differential pharmacological in vitro properties of organic cation transporters and regional distribution in rat brain.

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12 December 2020

Regulation of testis-specific carnitine transporter (octn3) gene by proximal cis-acting elements Sp1 in mice.

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12 December 2020

Interactions of HIV protease inhibitors with a human organic cation transporter in a mammalian expression system

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12 December 2020

cDNA cloning, functional characterization, and tissue distribution of an alternatively spliced variant of organic cation transporter hOCT2 predominantly expressed in the human kidney

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12 December 2020

Molecular cloning and functional expression of a rabbit renal organic cation transporter

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12 December 2020

Carriers involved in targeting the cytostatic bile acid-cisplatin derivatives cis-diammine-chloro-cholylglycinate-platinum(II) and cis-diammine-bisursodeoxycholate-platinum(II) toward liver cells.

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12 December 2020

Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate

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12 December 2020

Regulation of human organic cation transporter hOCT2 by PKA, PI3K, and calmodulin-dependent kinases

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12 December 2020

Molecular cloning and characterization of high-affinity carnitine transporter from rat intestine

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12 December 2020

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

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12 December 2020

Discovery of the ergothioneine transporter

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12 December 2020

Association between gene polymorphisms of SLC22A3 and methamphetamine use disorder

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12 December 2020

Organic cation transporters

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12 December 2020

Different affinities of inhibitors to the outwardly and inwardly directed substrate binding site of organic cation transporter 2

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12 December 2020

Molecular and functional characterization of organic cation/carnitine transporter family in mice

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12 December 2020

Ventricular choline transport: a role for organic cation transporter 2 expressed in choroid plexus

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12 December 2020

Cloning of the mouse organic cation transporter 2 gene, Slc22a2, from an enhancer-trap transgene integration locus.

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12 December 2020

A third human carnitine/organic cation transporter (OCTN3) as a candidate for the 5q31 Crohn's disease locus (IBD5)

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12 December 2020

Transporter gene expression in lactating and nonlactating human mammary epithelial cells using real-time reverse transcription-polymerase chain reaction

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12 December 2020

PDZK1 directly regulates the function of organic cation/carnitine transporter OCTN2

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12 December 2020

The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology

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12 December 2020

Characterization of organic cation/carnitine transporter family in human sperm

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12 December 2020

The organic cation transporters rOCT1 and hOCT2 are inhibited by cGMP.

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12 December 2020

Drug uptake systems in liver and kidney

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12 December 2020

Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognition

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12 December 2020

The transport of organic cations in the small intestine: current knowledge and emerging concepts

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12 December 2020

Functional and pharmacological characterization of human Na(+)-carnitine cotransporter hOCTN2.

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12 December 2020

Evidence for the association of the SLC22A4 and SLC22A5 genes with type 1 diabetes: a case control study

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12 December 2020

Gender differences in expression of organic cation transporter OCT2 in rat kidney

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12 December 2020

Infantile disease with microvesicular fatty infiltration of viscera spontaneously occurring in the C3H-H-2° strain of mouse with similarities to Reye's syndrome

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12 December 2020

Organic cation transporter mRNA and function in the rat superior cervical ganglion.

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12 December 2020

Regulation of the human organic cation transporter hOCT1.

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12 December 2020

Site-selective effect of bicarbonate on amantadine renal transport: quinine-sensitive in proximal vs quinidine-sensitive sites in distal tubules

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12 December 2020

Oligonucleotide microarray analysis of differential transporter regulation in the regenerating rat liver

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12 December 2020

An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis

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12 December 2020

Association of rheumatoid arthritis with ergothioneine levels in red blood cells: a case control study.

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12 December 2020

Functional regions of organic cation/carnitine transporter OCTN2 (SLC22A5): roles in carnitine recognition

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12 December 2020

Reduced hepatic uptake and intestinal excretion of organic cations in mice with a targeted disruption of the organic cation transporter 1 (Oct1 [Slc22a1]) gene

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12 December 2020

Human organic anion transporters and human organic cation transporters mediate renal antiviral transport

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12 December 2020

Properties and regulation of organic cation transport in freshly isolated human proximal tubules

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12 December 2020

Gene structures of the human non-neuronal monoamine transporters EMT and OCT2

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12 December 2020

Novel localization of OCTN1, an organic cation/carnitine transporter, to mammalian mitochondria

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12 December 2020

Organic cation transporter 3 (Slc22a3) is implicated in salt-intake regulation

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12 December 2020

Molecular cloning and characterization of two novel transport proteins from rat kidney.

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12 December 2020

cDNA cloning and functional expression of a novel rat kidney organic cation transporter, OCT2.

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12 December 2020

Cimetidine reduces procainamide elimination

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12 December 2020

beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter

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12 December 2020

The SLC22 drug transporter family

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12 December 2020

Increased plasma concentration and brain penetration of methamphetamine in behaviorally sensitized rats.

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12 December 2020

Characterization of L-carnitine transport by rat kidney brush-border-membrane vesicles

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12 December 2020

The localisation of the extraneuronal monoamine transporter (EMT) in rat brain

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12 December 2020

Interaction between intestinal absorption and secretion of monoquaternary ammonium compounds in guinea pigs--a concept for the absorption kinetics of organic cations.

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12 December 2020

Cisplatin and oxaliplatin, but not carboplatin and nedaplatin, are substrates for human organic cation transporters (SLC22A1-3 and multidrug and toxin extrusion family)

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12 December 2020

Functional analysis of organic cation transporter 3 expressed in human placenta

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12 December 2020

Expression of transporters potentially involved in the targeting of cytostatic bile acid derivatives to colon cancer and polyps.

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12 December 2020

Lipopolysaccharide-mediated regulation of hepatic transporter mRNA levels in rats

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12 December 2020

Organic cation transporter capable of transporting serotonin is up-regulated in serotonin transporter-deficient mice.

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12 December 2020

Regulation of human extraneuronal monoamine transporter (hEMT) expressed in HEK293 cells by intracellular second messenger systems

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12 December 2020

Expression profiles of various transporters for oligopeptides, amino acids and organic ions along the human digestive tract

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12 December 2020

Functional variants of OCTN cation transporter genes are associated with Crohn disease

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12 December 2020

Regulation of plasma choline by the renal tubule: bidirectional transport of choline.

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12 December 2020

Cloning and functional characterization of a rat renal organic cation transporter isoform (rOCT1A).

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12 December 2020

Characterization of L-carnitine transport into rat skeletal muscle plasma membrane vesicles

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12 December 2020

The two human organic cation transporter genes SLC22A1 and SLC22A2 are located on chromosome 6q26

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12 December 2020

Renal tubular transport and metabolism of organic cations by the rabbit

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12 December 2020

Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain

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12 December 2020

Expression and pharmacological profile of the human organic cation transporters hOCT1, hOCT2 and hOCT3

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12 December 2020

Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2.

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12 December 2020

Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1.

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12 December 2020

Carnitine transporter OCTN2 mutations in systemic primary carnitine deficiency: a novel Arg169Gln mutation and a recurrent Arg282ter mutation associated with an unconventional splicing abnormality

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12 December 2020

Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance

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12 December 2020

Molecular cloning, functional characterization and tissue distribution of rat H+/organic cation antiporter MATE1

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12 December 2020

Molecular identification and functional characterization of rat multidrug and toxin extrusion type transporter 1 as an organic cation/H+ antiporter in the kidney

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12 December 2020

Comparison of "type I" and "type II" organic cation transport by organic cation transporters and organic anion-transporting polypeptides

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12 December 2020

Na(+)-coupled transport of L-carnitine via high-affinity carnitine transporter OCTN2 and its subcellular localization in kidney

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12 December 2020

Molecular identification of the corticosterone-sensitive extraneuronal catecholamine transporter

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12 December 2020

The role of the V-ATPase in renal epithelial H+ transport

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12 December 2020

Molecular determinants of substrate/inhibitor binding to the human and rabbit renal organic cation transporters hOCT2 and rbOCT2.

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12 December 2020

Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease

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12 December 2020

The human basophil: a new appreciation of its role in immune responses

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12 December 2020

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

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12 December 2020

Cloning of the mouse and human solute carrier 22a3 (Slc22a3/SLC22A3) identifies a conserved cluster of three organic cation transporters on mouse chromosome 17 and human 6q26-q27

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12 December 2020

Behavioral changes following antisense oligonucleotide-induced reduction of organic cation transporter-3 in mice

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12 December 2020

The role of advanced glycation in reduced organic cation transport associated with experimental diabetes

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12 December 2020

Genetic epidemiology of the carnitine transporter OCTN2 gene in a Japanese population and phenotypic characterization in Japanese pedigrees with primary systemic carnitine deficiency

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12 December 2020

Transport of drugs in the kidney by the human organic cation transporter, OCT2 and its genetic variants

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12 December 2020

Recent advances in molecular pharmacology of the histamine systems: organic cation transporters as a histamine transporter and histamine metabolism

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12 December 2020

Molecular pharmacology of organic cation transporters in kidney

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12 December 2020

Lower prevalence of the OCT2 Ser270 allele in patients with essential hypertension

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12 December 2020

Are organic cation transporters capable of transporting prostaglandins?

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12 December 2020

Sex Differences in Organic Ion Transport by Rat Kidney

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12 December 2020

Mutations in novel organic cation transporter (OCTN2), an organic cation/carnitine transporter, with differential effects on the organic cation transport function and the carnitine transport function

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12 December 2020

Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties

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12 December 2020

Epithelial organic cation transporters ensure pH-dependent drug absorption in the airway

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12 December 2020

Loss of wild-type carrier-mediated L-carnitine transport activity in hepatocytes of juvenile visceral steatosis mice

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12 December 2020

Cardiac hypertrophy in juvenile visceral steatosis (jvs) mice with systemic carnitine deficiency

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12 December 2020

Identification of two novel mutations in OCTN2 of three patients with systemic carnitine deficiency

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12 December 2020

Kinetic and selectivity differences between rodent, rabbit, and human organic cation transporters (OCT1).

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12 December 2020

Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes.

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12 December 2020

Functional genetic diversity in the high-affinity carnitine transporter OCTN2 (SLC22A5).

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12 December 2020

Role of acetylcholine and polyspecific cation transporters in serotonin-induced bronchoconstriction in the mouse

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12 December 2020

The human organic cation transporter (hOCT2) recognizes the degree of substrate ionization

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12 December 2020

Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta

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12 December 2020

Drug excretion mediated by a new prototype of polyspecific transporter

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12 December 2020

Functional analysis of mutations in the OCTN2 transporter causing primary carnitine deficiency: lack of genotype-phenotype correlation.

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12 December 2020

cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family

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12 December 2020

Androgen receptor is responsible for rat organic cation transporter 2 gene regulation but not for rOCT1 and rOCT3.

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12 December 2020

A species difference in the transport activities of H2 receptor antagonists by rat and human renal organic anion and cation transporters

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12 December 2020

An overview of metformin in the treatment of type 2 diabetes mellitus

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12 December 2020

Chronic cardiomyopathy and weakness or acute coma in children with a defect in carnitine uptake

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12 December 2020

Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa)

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12 December 2020

A reevaluation of substrate specificity of the rat cation transporter rOCT1.

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12 December 2020

Electrogenic properties and substrate specificity of the polyspecific rat cation transporter rOCT1.

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12 December 2020

Agmatine is efficiently transported by non-neuronal monoamine transporters extraneuronal monoamine transporter (EMT) and organic cation transporter 2 (OCT2)

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12 December 2020

Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations

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12 December 2020

Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1

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12 December 2020

Identification of genetic variations of the human organic cation transporter hOCT1 and their functional consequences

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12 December 2020

Hormonal regulation of organic cation transporter OCT2 expression in rat kidney

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12 December 2020

Studies on functional sites of organic cation/carnitine transporter OCTN2 (SLC22A5) using a Ser467Cys mutant protein

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12 December 2020

Cloning and functional expression of a mouse liver organic cation transporter

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12 December 2020

Alkali cation binding and permeation in the rat organic cation transporter rOCT2.

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12 December 2020

Metformin and the polycystic ovary syndrome

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12 December 2020

Selective substrates for non-neuronal monoamine transporters

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12 December 2020

Purification and functional reconstitution of the rat organic cation transporter OCT1.

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12 December 2020

Organic cation transporter 3 modulates murine basophil functions by controlling intracellular histamine levels

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12 December 2020

Polyspecific organic cation transporters: their functions and interactions with drugs

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12 December 2020

Differential localization of organic cation transporters rOCT1 and rOCT2 in the basolateral membrane of rat kidney proximal tubules

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12 December 2020

Deficiency in the organic cation transporters 1 and 2 (Oct1/Oct2 [Slc22a1/Slc22a2]) in mice abolishes renal secretion of organic cations

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12 December 2020

Wide variety of locations for rodent MATE1, a transporter protein that mediates the final excretion step for toxic organic cations

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12 December 2020

Constitutive expression of various xenobiotic and endobiotic transporter mRNAs in the choroid plexus of rats

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12 December 2020

Interactions between cimetidine, nitrofurantoin, and probenecid active transport into rat milk

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12 December 2020

Interactions of n-tetraalkylammonium compounds and biguanides with a human renal organic cation transporter (hOCT2).

1 reference

12 December 2020

Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney

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12 December 2020

Functional role of the 503F variant of the organic cation transporter OCTN1 in Crohn's disease

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12 December 2020

A missense mutation in the OCTN2 gene associated with residual carnitine transport activity

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12 December 2020

The affinity of the organic cation transporter rOCT1 is increased by protein kinase C-dependent phosphorylation

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12 December 2020

Functional impairment of renal organic cation transport in experimental diabetes

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12 December 2020

Sodium gradient-stimulated transport of L-carnitine into renal brush border membrane vesicles: kinetics, specificity, and regulation by dietary carnitine

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12 December 2020

Cloning and functional expression of a human liver organic cation transporter

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12 December 2020

Fourteen novel single nucleotide polymorphisms in the SLC22A2 gene encoding human organic cation transporter (OCT2)

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12 December 2020

Human organic anion transporters and human organic cation transporters mediate renal transport of prostaglandins.

1 reference

12 December 2020

Gender-associated differences in rat renal tubular amantadine transport and absence of stereoselective transport inhibition by quinine and quinidine in distal tubules

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12 December 2020

Seven novel single nucleotide polymorphisms in the human SLC22A1 gene encoding organic cation transporter 1 (OCT1)

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12 December 2020

Molecular evidence of organic ion transporters in the rat adrenal cortex with adrenocorticotropin-regulated zonal expression

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12 December 2020

Functional characterization of mouse cation transporter mOCT2 compared with mOCT1

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12 December 2020

Phenotype and genotype variation in primary carnitine deficiency

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12 December 2020

Current status of genetics research in inflammatory bowel disease.

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12 December 2020

Local inhibition of organic cation transporters increases extracellular serotonin in the medial hypothalamus.

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12 December 2020

Major facilitator superfamily

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12 December 2020

Functional expression of the organic cation/carnitine transporter 2 in rat astrocytes

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12 December 2020

Cysteine accessibility in the hydrophilic cleft of human organic cation transporter 2.

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12 December 2020

Identification of OCT6 as a novel organic cation transporter preferentially expressed in hematopoietic cells and leukemias

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12 December 2020

Subtype-specific affinity for corticosterone of rat organic cation transporters rOCT1 and rOCT2 depends on three amino acids within the substrate binding region

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12 December 2020

Transporters involved in the elimination of drugs in the kidney: organic anion transporters and organic cation transporters

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12 December 2020

Impaired activity of the extraneuronal monoamine transporter system known as uptake-2 in Orct3/Slc22a3-deficient mice

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12 December 2020

10.1007/S11095-007-9254-Z

Identifiers

DOI

1 reference

16 August 2017

1 reference

PubMed ID

17473959