(Q36812466)

English

Cofactor balance by nicotinamide nucleotide transhydrogenase (NNT) coordinates reductive carboxylation and glucose catabolism in the tricarboxylic acid (TCA) cycle

scientific article published on 15 March 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Cofactor balance by nicotinamide nucleotide transhydrogenase (NNT) coordinates reductive carboxylation and glucose catabolism in the tricarboxylic acid (TCA) cycle (English)

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

1 reference

based on heuristic

inferred from title

Gregory Stephanopoulos

5

object named as

Gregory Stephanopoulos

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

author name string

Paulo A Gameiro

1

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Laura A Laviolette

2

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Joanne K Kelleher

3

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Othon Iliopoulos

4

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Europe PubMed Central

PMC publication ID

16 August 2017

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publication date

15 March 2013

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Europe PubMed Central

PMC publication ID

16 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

16 August 2017

288

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Europe PubMed Central

PMC publication ID

16 August 2017

18

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

12967-12977

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

In vivo HIF-mediated reductive carboxylation is regulated by citrate levels and sensitizes VHL-deficient cells to glutamine deprivation

1 reference

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Mutations in NNT encoding nicotinamide nucleotide transhydrogenase cause familial glucocorticoid deficiency

1 reference

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1 reference

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1 reference

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Cancer-associated isocitrate dehydrogenase mutations inactivate NADPH-dependent reductive carboxylation

1 reference

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Silencing of nicotinamide nucleotide transhydrogenase impairs cellular redox homeostasis and energy metabolism in PC12 cells

1 reference

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1 reference

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1 reference

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Glutamine addiction: a new therapeutic target in cancer

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Diet-induced obesity in two C57BL/6 substrains with intact or mutant nicotinamide nucleotide transhydrogenase (Nnt) gene

1 reference

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Glutamine-dependent anapleurosis dictates glucose uptake and cell growth by regulating MondoA transcriptional activity.

1 reference

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Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2.

1 reference

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Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

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Quantifying reductive carboxylation flux of glutamine to lipid in a brown adipocyte cell line

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The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

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Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

1 reference

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The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis

1 reference

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HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

1 reference

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Nicotinamide nucleotide transhydrogenase: a key role in insulin secretion

1 reference

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Distribution of mitochondrial NADH fluorescence lifetimes: steady-state kinetics of matrix NADH interactions.

1 reference

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1 reference

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of NADH shuttle system in glucose-induced activation of mitochondrial metabolism and insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/23504317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial NADPH, transhydrogenase and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23504317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[The enzymatic properties of isocitric dehydrogenase]

1 reference

https://pubmed.ncbi.nlm.nih.gov/23504317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.396796

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

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