(Q36817224)

English

A small molecule antagonist inhibits thyrotropin receptor antibody-induced orbital fibroblast functions involved in the pathogenesis of Graves ophthalmopathy

scientific article published on 12 March 2013

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scholarly article

1 reference

Europe PubMed Central

16 August 2017

A small molecule antagonist inhibits thyrotropin receptor antibody-induced orbital fibroblast functions involved in the pathogenesis of Graves ophthalmopathy (English)

1 reference

Europe PubMed Central

16 August 2017

Graves' ophthalmopathy

1 reference

based on heuristic

inferred from title

author name string

Adina F Turcu

1

1 reference

Europe PubMed Central

16 August 2017

Seema Kumar

2

1 reference

Europe PubMed Central

16 August 2017

Susanne Neumann

3

1 reference

Europe PubMed Central

16 August 2017

Michael Coenen

4

1 reference

Europe PubMed Central

16 August 2017

Seethalakshmi Iyer

5

1 reference

Europe PubMed Central

16 August 2017

Pamela Chiriboga

6

1 reference

Europe PubMed Central

16 August 2017

Marvin C Gershengorn

7

1 reference

Europe PubMed Central

16 August 2017

Rebecca S Bahn

8

1 reference

Europe PubMed Central

16 August 2017

language of work or name

0 references

publication date

12 March 2013

1 reference

Europe PubMed Central

16 August 2017

The Journal of Clinical Endocrinology and Metabolism

1 reference

Europe PubMed Central

16 August 2017

98

1 reference

Europe PubMed Central

16 August 2017

5

1 reference

Europe PubMed Central

16 August 2017

2153-2159

1 reference

Europe PubMed Central

16 August 2017

Update in TSH receptor agonists and antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644605

29 September 2017

A drug-like antagonist inhibits thyrotropin receptor-mediated stimulation of cAMP production in Graves' orbital fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644605

29 September 2017

Autoimmunity and Graves' disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644605

29 September 2017

A stimulatory thyrotropin receptor antibody enhances hyaluronic acid synthesis in graves' orbital fibroblasts: inhibition by an IGF-I receptor blocking antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644605

29 September 2017

Mechanism of action of a nanomolar potent, allosteric antagonist of the thyroid-stimulating hormone receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644605

29 September 2017

Small-molecule thyrotropin receptor agonist activates naturally occurring thyrotropin-insensitive mutants and reveals their distinct cyclic adenosine monophosphate signal persistence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644605

29 September 2017

Autoimmunity in Graves' ophthalmopathy: the result of an unfortunate marriage between TSH receptors and IGF-1 receptors?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644605

29 September 2017

Thyrotropin receptor stimulates internalization-independent persistent phosphoinositide signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644605

29 September 2017

A stimulatory TSH receptor antibody enhances adipogenesis via phosphoinositide 3-kinase activation in orbital preadipocytes from patients with Graves' ophthalmopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644605

29 September 2017

A new small-molecule antagonist inhibits Graves' disease antibody activation of the TSH receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644605

29 September 2017

Pathogenesis of Graves' orbitopathy: a 2010 update.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644605

29 September 2017

A small molecule inverse agonist for the human thyroid-stimulating hormone receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644605

29 September 2017

Graves' ophthalmopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644605

29 September 2017

Thyrotropin receptor activation increases hyaluronan production in preadipocyte fibroblasts: contributory role in hyaluronan accumulation in thyroid dysfunction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644605

29 September 2017

Characterization of thyrotropin receptor antibody-induced signaling cascades

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644605

29 September 2017

A low-molecular-weight antagonist for the human thyrotropin receptor with therapeutic potential for hyperthyroidism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644605

29 September 2017

Stimulation of adipogenesis, peroxisome proliferator-activated receptor-gamma (PPARgamma), and thyrotropin receptor by PPARgamma agonist in human orbital preadipocyte fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644605

29 September 2017

Complete inhibition of rhTSH-, Graves' disease IgG-, and M22-induced cAMP production in differentiated orbital fibroblasts by a low-molecular-weight TSHR antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644605

5 September 2018

Effects of thyrotropin and thyrotropin-receptor-stimulating Graves' disease immunoglobulin G on cyclic adenosine monophosphate and hyaluronan production in nondifferentiated orbital fibroblasts of Graves' ophthalmopathy patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644605

5 September 2018

Human monoclonal thyroid stimulating autoantibody.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644605

5 September 2018

Presence of antibodies in the sera of patients with Graves' disease recognizing a 23 kilodalton fibroblast protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/23482611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation of human orbital preadipocyte fibroblasts induces expression of functional thyrotropin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/23482611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thyrotropin receptor-stimulating Graves' disease immunoglobulins induce hyaluronan synthesis by differentiated orbital fibroblasts from patients with Graves' ophthalmopathy not only via cyclic adenosine monophosphate signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/23482611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1210/JC.2013-1149

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

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