(Q36818068)

English

Lipopolysaccharide clearance, bacterial clearance, and systemic inflammatory responses are regulated by cell type-specific functions of TLR4 during sepsis

scientific article published on 5 April 2013

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Lipopolysaccharide clearance, bacterial clearance, and systemic inflammatory responses are regulated by cell type-specific functions of TLR4 during sepsis (English)

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

0 references

lipopolysaccharide

0 references

toll-like receptor

0 references

Timothy Billiar

8

object named as

Timothy R Billiar

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

author name string

Meihong Deng

1

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Melanie J Scott

2

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Patricia Loughran

3

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Gregory Gibson

4

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Chhinder Sodhi

5

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Simon Watkins

6

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

David Hackam

7

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

language of work or name

0 references

publication date

5 April 2013

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Journal of Immunology

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

190

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

10

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

5152-5160

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Intestinal epithelial Toll-like receptor 4 regulates goblet cell development and is required for necrotizing enterocolitis in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Moraxella catarrhalis activates murine macrophages through multiple toll like receptors and has reduced clearance in lungs from TLR4 mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

TLR2, TLR4 and the MYD88 signaling pathway are crucial for neutrophil migration in acute kidney injury induced by sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Hepatic uptake and deacylation of the LPS in bloodborne LPS-lipoprotein complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Current insights in sepsis: from pathogenesis to new treatment targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

The Toll-like receptor 4 agonist monophosphoryl lipid a augments innate host resistance to systemic bacterial infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Toll-like receptor-4 antagonist eritoran tetrasodium for severe sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Toll-like receptors in acute liver injury and regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Innate immune signaling in cardiac ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Early enhanced local neutrophil recruitment in peritonitis-induced sepsis improves bacterial clearance and survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Impaired Cd14 and Cd36 expression, bacterial clearance, and Toll-like receptor 4-Myd88 signaling in caveolin-1-deleted macrophages and mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Both TRIF- and MyD88-dependent signaling contribute to host defense against pulmonary Klebsiella infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Pattern recognition by Toll-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Early use of polymyxin B hemoperfusion in abdominal septic shock: the EUPHAS randomized controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Endotoxin uptake in mouse liver is blocked by endotoxin pretreatment through a suppressor of cytokine signaling-1-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Inefficient Toll-like receptor-4 stimulation enables Bordetella parapertussis to avoid host immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Immunodesign of experimental sepsis by cecal ligation and puncture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

MyD88 dependent signaling contributes to protective host defense against Burkholderia pseudomallei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Toll-like receptor 4 plays a role in macrophage phagocytosis during peritoneal sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

How important are Toll-like receptors for antimicrobial responses?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Effectiveness of polymyxin B-immobilized fiber column in sepsis: a systematic review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Sepsis-induced organ failure is mediated by different pathways in the kidney and liver: acute renal failure is dependent on MyD88 but not renal cell apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

TLR4 signaling is essential for survival in acute lung injury induced by virulent Pseudomonas aeruginosa secreting type III secretory toxins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity [corrected]

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Shock-induced neutrophil mediated priming for acute lung injury in mice: divergent effects of TLR-4 and TLR-4/FasL deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Differences in innate defense mechanisms in endotoxemia and polymicrobial septic peritonitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Sepsis: a pro- and anti-inflammatory disequilibrium syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Role of hepatocytes in direct clearance of lipopolysaccharide in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Comparative studies of endotoxin uptake by isolated rat Kupffer and peritoneal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Bacterial Endotoxins and Host Immune Responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

Genetic defect in responsiveness to the B cell mitogen lipopolysaccharide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

29 September 2017

The Asp299Gly polymorphism alters TLR4 signaling by interfering with recruitment of MyD88 and TRIF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

27 June 2018

A randomized, double-blind, placebo-controlled trial of TAK-242 for the treatment of severe sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

5 September 2018

Beta2-integrin-induced p38 MAPK activation is a key mediator in the CD14/TLR4/MD2-dependent uptake of lipopolysaccharide by hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

5 September 2018

Deletion of MyD88 markedly attenuates sepsis-induced T and B lymphocyte apoptosis but worsens survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

5 September 2018

Toll-like receptor 4 signaling leads to neutrophil migration impairment in polymicrobial sepsis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

5 September 2018

TLR-4 pathway mediates the inflammatory response but not bacterial elimination in E. coli pneumonia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

5 September 2018

Generation and functional characterization of a clonal murine periportal Kupffer cell line from H-2Kb -tsA58 mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

5 September 2018

Association between the Asp299Gly polymorphisms in the Toll-like receptor 4 and premature births in the Finnish population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

5 September 2018

Hepatic endosomal trafficking of lipoprotein-bound endotoxin in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

5 September 2018

Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

5 September 2018

Conditional gene targeting in macrophages and granulocytes using LysMcre mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

5 September 2018

Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644895

5 September 2018

Combination of imipenem and TAK-242, a Toll-like receptor 4 signal transduction inhibitor, improves survival in a murine model of polymicrobial sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23562812

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of myocardial dysfunction in sepsis: the Toll-like receptor antagonist approach

1 reference

https://pubmed.ncbi.nlm.nih.gov/23562812

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of a novel mechanism of accelerated bacterial clearance by lipopolysaccharide in CD14-deficient and Toll-like receptor 4-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23562812

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hepatocyte as a microbial product-responsive cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/23562812

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of cytokine tolerance requires internalization of Chylomicron-Bound LPS into hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23562812

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the in vivo clearance and detoxification of endotoxin by lung and liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/23562812

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The clearance, tissue distribution, and cellular localization of intravenously injected lipopolysaccharide in rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/23562812

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sepsis increases endocytosis of endotoxin into hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23562812

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23562812

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatocytes enhance effects of lipopolysaccharide on liver nonparenchymal cells through close cell interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/23562812

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.1300496

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q36818068&oldid=2086478069"