(Q36823697)

16 August 2017

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title

Current status of cardiovascular gene therapy (English)

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16 August 2017

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2

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16 August 2017

1

Tuomas T Rissanen

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16 August 2017

8 May 2007

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16 August 2017

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16 August 2017

15

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16 August 2017

7

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16 August 2017

1233-1247

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Cardiovascular gene therapy

16 August 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Tumour angiogenesis factor for revascularisation in ischaemia and myocardial infarction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Salvage of infarcted myocardium by angiogenic action of basic fibroblast growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

The VIVA trial: Vascular endothelial growth factor in Ischemia for Vascular Angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (the TRAFFIC study): a randomised trial

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Pharmacological treatment of coronary artery disease with recombinant fibroblast growth factor-2: double-blind, randomized, controlled clinical trial

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Adenoviral-mediated gene transfer induces sustained pericardial VEGF expression in dogs: effect on myocardial angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Gene transfer as a tool to induce therapeutic vascular growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Direct intramuscular gene transfer of naked DNA encoding vascular endothelial growth factor augments collateral development and tissue perfusion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Treatment of thromboangiitis obliterans (Buerger's disease) by intramuscular gene transfer of vascular endothelial growth factor: preliminary clinical results

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Randomized, single-blind, placebo-controlled pilot study of catheter-based myocardial gene transfer for therapeutic angiogenesis using left ventricular electromechanical mapping in patients with chronic myocardial ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

One-year follow-up of direct myocardial gene transfer of vascular endothelial growth factor-2 using naked plasmid deoxyribonucleic acid by way of thoracotomy in no-option patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Increased vascularity detected by digital subtraction angiography after VEGF gene transfer to human lower limb artery: a randomized, placebo-controlled, double-blinded phase II study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Safety and Feasibility of Catheter-Based Local Intracoronary Vascular Endothelial Growth Factor Gene Transfer in the Prevention of Postangioplasty and In-Stent Restenosis and in the Treatment of Chronic Myocardial Ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Direct intramyocardial plasmid vascular endothelial growth factor-A165 gene therapy in patients with stable severe angina pectoris A randomized double-blind placebo-controlled study: the Euroinject One trial

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Treatment with intramuscular vascular endothelial growth factor gene compared with placebo for patients with diabetes mellitus and critical limb ischemia: a double-blind randomized trial.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Gene transfer into the carotid artery using an adventitial collar: comparison of the effectiveness of the plasmid-liposome complexes, retroviruses, pseudotyped retroviruses, and adenoviruses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

In vivo myocardial gene transfer: Optimization, evaluation and direct comparison of gene transfer vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Adenoviral catheter-mediated intramyocardial gene transfer using the mature form of vascular endothelial growth factor-D induces transmural angiogenesis in porcine heart.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Myocardial angiogenesis after plasmid or adenoviral VEGF-A(165) gene transfer in rat myocardial infarction model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Electropermeabilization of skeletal muscle enhances gene transfer in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

In vivo gene transfer into muscle via electro-sonoporation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

beta-Galactosidase staining following intracoronary infusion of cationic liposomes in the in vivo rabbit heart is produced by microinfarction rather than effective gene transfer: a cautionary tale

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Inflammatory responses following direct injection of plasmid DNA into skeletal muscle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Long-term lowering of plasma cholesterol levels in LDL-receptor-deficient WHHL rabbits by gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Third-generation lentivirus vectors efficiently transduce and phenotypically modify vascular cells: implications for gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Feline immunodeficiency virus and retrovirus-mediated adventitial ex vivo gene transfer to rabbit carotid artery using autologous vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Multiply attenuated, self-inactivating lentiviral vectors efficiently transduce human coronary artery cells in vitro and rat arteries in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Baculovirus-mediated periadventitial gene transfer to rabbit carotid artery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Efficacy and safety of edifoligide, an E2F transcription factor decoy, for prevention of vein graft failure following coronary artery bypass graft surgery: PREVENT IV: a randomized controlled trial

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Results of PREVENT III: a multicenter, randomized trial of edifoligide for the prevention of vein graft failure in lower extremity bypass surgery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

The potential of oligonucleotides for therapeutic applications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Vascular permeability effect of adenovirus-mediated vascular endothelial growth factor gene transfer to the rabbit and rat skeletal muscle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Biology of E1-deleted adenovirus vectors in nonhuman primate muscle.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Blood flow remodels growing vasculature during vascular endothelial growth factor gene therapy and determines between capillary arterialization and sprouting angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Improved vascular gene transfer with a helper-dependent adenoviral vector

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Expression of the primary coxsackie and adenovirus receptor is downregulated during skeletal muscle maturation and limits the efficacy of adenovirus-mediated gene delivery to muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Evaluation of angiogenesis and side effects in ischemic rabbit hindlimbs after intramuscular injection of adenoviral vectors encoding VEGF and LacZ.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Adenovirus-mediated gene transfer to lower limb artery of patients with chronic critical leg ischemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Fibroblast growth factor 4 induces vascular permeability, angiogenesis and arteriogenesis in a rabbit hindlimb ischemia model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Adenovirus vectors based on human adenovirus type 19a have high potential for human muscle-directed gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

In vitro and in vivo characterisation of endothelial cell selective adenoviral vectors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Gene transfer into rabbit arteries with adeno-associated virus and adenovirus vectors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

AAV serotype-1 mediates early onset of gene expression in mouse hearts and results in better therapeutic effect

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Genetic fate of recombinant adeno-associated virus vector genomes in muscle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heart

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Widespread and early myocardial gene expression by adeno-associated virus vector type 6 with a beta-actin hybrid promoter.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Recombinant adeno-associated virus serotype 9 leads to preferential cardiac transduction in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Vascular bed-targeted in vivo gene delivery using tropism-modified adeno-associated viruses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Evidence of multiyear factor IX expression by AAV-mediated gene transfer to skeletal muscle in an individual with severe hemophilia B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Cardiomyocyte-specific gene expression following recombinant adeno-associated viral vector transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Adeno-associated viral vector delivers cardiac-specific and hypoxia-inducible VEGF expression in ischemic mouse hearts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Local adenovirus-mediated transfer of human endothelial nitric oxide synthase reduces luminal narrowing after coronary angioplasty in pigs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Local gene transfer of phVEGF-2 plasmid by gene-eluting stents: an alternative strategy for inhibition of restenosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Gene-eluting stents: comparison of adenoviral and adeno- associated viral gene delivery to the blood vessel wall in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Extracellular superoxide dismutase with vaccinia virus anti-inflammatory protein 35K or tissue inhibitor of metalloproteinase-1: Combination gene therapy in the treatment of vein graft stenosis in rabbits

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

In vivo myocardial gene transfer: optimization and evaluation of intracoronary gene delivery in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Focal angiogen therapy using intramyocardial delivery of an adenovirus vector coding for vascular endothelial growth factor 121.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

VEGF gene delivery to muscle: potential role for vasculogenesis in adults

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

VEGF gene delivery to myocardium: deleterious effects of unregulated expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Enhanced plasma cholesterol lowering effect of retrovirus-mediated LDL receptor gene transfer to WHHL rabbit liver after improved surgical technique and stimulation of hepatocyte proliferation by combined partial liver resection and thymidine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Vascular endothelial growth factors: biology and current status of clinical applications in cardiovascular medicine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Adenovirus‐mediated VEGF‐A gene transfer induces bone formationin vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Improved survival of ischemic cutaneous and musculocutaneous flaps after vascular endothelial growth factor gene transfer using adeno-associated virus vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Adeno-associated viral-vector-mediated hypoxia-inducible vascular endothelial growth factor gene expression attenuates ischemic brain injury after focal cerebral ischemia in mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Adenovirus-mediated VEGF(121) gene transfer stimulates angiogenesis in normoperfused skeletal muscle and preserves tissue perfusion after induction of ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Heterogeneity of the angiogenic response induced in different normal adult tissues by vascular permeability factor/vascular endothelial growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Localized arteriole formation directly adjacent to the site of VEGF-induced angiogenesis in muscle.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Induction of functional neovascularization by combined VEGF and angiopoietin-1 gene transfer using AAV vectors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

A VEGF165-induced phenotypic switch from increased vessel density to increased vessel diameter and increased endothelial NOS activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Magnetic resonance angiography reveals therapeutic enlargement of collateral vessels induced by VEGF in a murine model of peripheral arterial disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

The range of adaptation by collateral vessels after femoral artery occlusion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Bone marrow mononuclear cells are recruited to the sites of VEGF-induced neovascularization but are not incorporated into the newly formed vessels.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Angiogenesis is induced in a rabbit model of hindlimb ischemia by naked DNA encoding an HIF-1alpha/VP16 hybrid transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Adenovirus-mediated transfer of a minigene expressing multiple isoforms of VEGF is more effective at inducing angiogenesis than comparable vectors expressing individual VEGF cDNAs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Chimeric VEGF-E(NZ7)/PlGF promotes angiogenesis via VEGFR-2 without significant enhancement of vascular permeability and inflammation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Vascular endothelial growth factor-C gene therapy restores lymphatic flow across incision wounds.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

A novel type of vascular endothelial growth factor, VEGF-E (NZ-7 VEGF), preferentially utilizes KDR/Flk-1 receptor and carries a potent mitotic activity without heparin-binding domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Vascular endothelial growth factor-B promotes in vivo angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Adenovirus-Mediated Gene Transfer of Placental Growth Factor to Perivascular Tissue Induces Angiogenesis via Upregulation of the Expression of Endogenous Vascular Endothelial Growth Factor-A

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Compensation by fibroblast growth factor 1 (FGF1) does not account for the mild phenotypic defects observed in FGF2 null mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

In vivo angiogenesis induced by recombinant adenovirus vectors coding either for secreted or nonsecreted forms of acidic fibroblast growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Adenovirus-mediated expression of the secreted form of basic fibroblast growth factor (FGF-2) induces cellular proliferation and angiogenesis in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in an ischemic region of the heart

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Pericyte loss and microaneurysm formation in PDGF-B-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Polymeric system for dual growth factor delivery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Revascularization of ischemic tissues by PDGF-CC via effects on endothelial cells and their progenitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Transgenic overexpression of platelet-derived growth factor-C in the mouse heart induces cardiac fibrosis, hypertrophy, and dilated cardiomyopathy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Angiogenesis induced by hepatocyte growth factor in non-infarcted myocardium and infarcted myocardium: up-regulation of essential transcription factor for angiogenesis, ets.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Angiopoietin-1 protects the adult vasculature against plasma leakage.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Long-term and sustained COMP-Ang1 induces long-lasting vascular enlargement and enhanced blood flow.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Constitutively active HIF-1alpha improves perfusion and arterial remodeling in an endovascular model of limb ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Human endothelial nitric oxide synthase gene delivery promotes angiogenesis in a rat model of hindlimb ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Monocyte Chemotactic Protein-1 Increases Collateral and Peripheral Conductance After Femoral Artery Occlusion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Neovascularization of ischemic tissues by gene delivery of the extracellular matrix protein Del-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Gene transfer of stromal cell-derived factor-1alpha enhances ischemic vasculogenesis and angiogenesis via vascular endothelial growth factor/endothelial nitric oxide synthase-related pathway: next-generation chemokine therapy for therapeutic neovasc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Adrenomedullin gene transfer induces therapeutic angiogenesis in a rabbit model of chronic hind limb ischemia: benefits of a novel nonviral vector, gelatin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Id1 gene transfer confers angiogenic property on fully differentiated endothelial cells and contributes to therapeutic angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Sonic hedgehog myocardial gene therapy: tissue repair through transient reconstitution of embryonic signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Netrins promote developmental and therapeutic angiogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

START Trial: a pilot study on STimulation of ARTeriogenesis using subcutaneous application of granulocyte-macrophage colony-stimulating factor as a new treatment for peripheral vascular disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Intramuscular vascular endothelial growth factor gene therapy in patients with chronic critical leg ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Left ventricular electromechanical mapping to assess efficacy of phVEGF(165) gene transfer for therapeutic angiogenesis in chronic myocardial ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Myocardial Doppler tissue velocity improves following myocardial gene therapy with VEGF-A165 plasmid in patients with inoperable angina pectoris

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Intramyocardial injection of vascular endothelial growth factor-A165 plasmid followed by granulocyte-colony stimulating factor to induce angiogenesis in patients with severe chronic ischaemic heart disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Long-term (2-year) clinical events following transthoracic intramyocardial gene transfer of VEGF-2 in no-option patients.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Adenovirus-mediated gene transfer of VEGF(121) improves lower-extremity endothelial function and flow reserve

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Use of a constitutively active hypoxia-inducible factor-1alpha transgene as a therapeutic strategy in no-option critical limb ischemia patients: phase I dose-escalation experience

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Regional angiogenesis with vascular endothelial growth factor in peripheral arterial disease: a phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermitt

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Catheter-mediated vascular endothelial growth factor gene transfer to human coronary arteries after angioplasty

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Angiogenic Gene Therapy (AGENT) trial in patients with stable angina pectoris

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

A randomized, double-blind, placebo-controlled trial of Ad5FGF-4 gene therapy and its effect on myocardial perfusion in patients with stable angina

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Phase 1/2 placebo-controlled, double-blind, dose-escalating trial of myocardial vascular endothelial growth factor 2 gene transfer by catheter delivery in patients with chronic myocardial ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Angiogenic gene therapy in patients with nonrevascularizable ischemic heart disease: a phase 2 randomized, controlled trial of AdVEGF(121) (AdVEGF121) versus maximum medical treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Therapeutic angiogenesis for critical limb ischemia: design of the hepatocyte growth factor therapeutic angiogenesis clinical trial

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Oral imatinib mesylate (STI571/gleevec) improves the efficacy of local intravascular vascular endothelial growth factor-C gene transfer in reducing neointimal growth in hypercholesterolemic rabbits

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Gene transfer using the mature form of VEGF-D reduces neointimal thickening through nitric oxide-dependent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Angiogenesis-Dependent and Independent Phases of Intimal Hyperplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

VEGF-A, VEGF-D and VEGF-D(DeltaNDeltaC) induced intimal hyperplasia in carotid arteries

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Human endothelial nitric oxide synthase gene transfer inhibits vascular smooth muscle cell proliferation and neointima formation after balloon injury in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Prostacyclin synthase gene transfer accelerates reendothelialization and inhibits neointimal formation in rat carotid arteries after balloon injury

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Adenovirus-mediated extracellular superoxide dismutase gene therapy reduces neointima formation in balloon-denuded rabbit aorta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Local intracoronary administration of antisense oligonucleotide against c-myc for the prevention of in-stent restenosis: results of the randomized investigation by the Thoraxcenter of antisense DNA using local delivery and IVUS after coronary stenti

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Gene transfer to coronary artery bypass conduits

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Adenovirus-mediated expression of beta-adrenergic receptor kinase C-terminus reduces intimal hyperplasia and luminal stenosis of arteriovenous polytetrafluoroethylene grafts in pigs.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Adenovirus-mediated gene transfer of human inducible nitric oxide synthase in porcine vein grafts inhibits intimal hyperplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Tissue inhibitor of metalloproteinase 1 adenoviral gene therapy alone is equally effective in reducing restenosis as combination gene therapy in a rabbit restenosis model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Gene therapy for ischemic cardiovascular diseases: some lessons learned from the first clinical trials

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Genentech discloses safety concerns over Avastin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Vascular endothelial growth factor enhances cardiac allograft arteriosclerosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Combined angiopoietin-1 and vascular endothelial growth factor gene transfer restores cavernous angiogenesis and erectile function in a rat model of hypercholesterolemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Angiopoietin-1 Protects Against the Development of Cardiac Allograft Arteriosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Common protective and diverse smooth muscle cell effects of AAV-mediated angiopoietin-1 and -2 expression in rat cardiac allograft vasculopathy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Adenovirus-mediated gene transfer of soluble vascular cell adhesion molecule to porcine interposition vein grafts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Anti-MCP-1 gene therapy inhibits vascular smooth muscle cells proliferation and attenuates vein graft thickening both in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Ex-vivo gene therapy of human vascular bypass grafts with E2F decoy: the PREVENT single-centre, randomised, controlled trial

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Controlled release of small interfering RNA targeting midkine attenuates intimal hyperplasia in vein grafts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Gene therapy with novel adeno-associated virus vectors substantially diminishes atherosclerosis in a murine model of familial hypercholesterolemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Adeno-associated virus-mediated gene transfer of a secreted decoy human macrophage scavenger receptor reduces atherosclerotic lesion formation in LDL receptor knockout mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Complete prevention of atherosclerosis in apoE-deficient mice by hepatic human apoE gene transfer with adeno-associated virus serotypes 7 and 8.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Non-physiological overexpression of the low density lipoprotein receptor (LDLr) gene in the liver induces pathological intracellular lipid and cholesterol storage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Potent reduction of apolipoprotein B and low-density lipoprotein cholesterol by short-term administration of an antisense inhibitor of apolipoprotein B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Prevention of arterial thrombosis by adenovirus-mediated transfer of cyclooxygenase gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Gene therapy to promote thromboresistance: local overexpression of tissue plasminogen activator to prevent arterial thrombosis in an in vivo rabbit model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Local overexpression of thrombomodulin for in vivo prevention of arterial thrombosis in a rabbit model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Thromboresistance of balloon-injured porcine carotid arteries after local gene transfer of human tissue factor pathway inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Accelerated reendothelialization with suppressed thrombogenic property and neointimal hyperplasia of rabbit jugular vein grafts by adenovirus-mediated gene transfer of C-type natriuretic peptide.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Adenovirus-mediated transfer of human placental ectonucleoside triphosphate diphosphohydrolase to vascular smooth muscle cells suppresses platelet aggregation in vitro and arterial thrombus formation in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Potential of gene therapy strategy for the treatment of hypertension

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Targeting endothelial cells with adenovirus expressing nitric oxide synthase prevents elevation of blood pressure in stroke-prone spontaneously hypertensive rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Sustained inhibition of angiotensin I-converting enzyme (ACE) expression and long-term antihypertensive action by virally mediated delivery of ACE antisense cDNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Recombinant adeno-associated virus-mediated kallikrein gene therapy reduces hypertension and attenuates its cardiovascular injuries

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Regulatable atrial natriuretic peptide gene therapy for hypertension

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Gene transfer of human prostacyclin synthase ameliorates monocrotaline-induced pulmonary hypertension in rats.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Gene therapy with adenovirus-mediated myocardial transfer of vascular endothelial growth factor 121 improves cardiac performance in a pacing model of congestive heart failure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

In vivo acceleration of heart relaxation performance by parvalbumin gene delivery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Cardiac adenoviral S100A1 gene delivery rescues failing myocardium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Enhancement of cardiac function after adenoviral-mediated in vivo intracoronary beta2-adrenergic receptor gene delivery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Pharmacological- and gene therapy-based inhibition of protein kinase Calpha/beta enhances cardiac contractility and attenuates heart failure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

p38 Kinase rescues failing myocardium after myocardial infarction: evidence for angiogenic and anti-apoptotic mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Blocking caspase-activated apoptosis improves contractility in failing myocardium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Intracoronary adenovirus encoding adenylyl cyclase VI increases left ventricular function in heart failure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Gene therapy strategy for long-term myocardial protection using adeno-associated virus-mediated delivery of heme oxygenase gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Genes, stem cells and biological pacemakers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Gene transfer of a synthetic pacemaker channel into the heart: a novel strategy for biological pacing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Bioartificial sinus node constructed via in vivo gene transfer of an engineered pacemaker HCN Channel reduces the dependence on electronic pacemaker in a sick-sinus syndrome model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: a randomised, controlled study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300175

7 January 2021

Identifiers

DOI

10.1038/SJ.MT.6300175

1 reference

16 August 2017

1 reference

PubMed ID

17505481