(Q36823796)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23466691%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

title

mTOR activation is required for the anti-alcohol effect of ketamine, but not memantine, in alcohol-preferring rats (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23466691%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23466691%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Luca Steardo

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23466691%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Pietro Cottone

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23466691%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

author name string

Aditi R Narayan

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23466691%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Tamara Zeric

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23466691%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

language of work or name

English

0 references

publication date

4 March 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23466691%20AND%20SRC:MED&resulttype=core&format=json

Behavioural Brain Research

25 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23466691%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

volume

247

1 reference

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25 February 2020

page(s)

9-16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23466691%20AND%20SRC:MED&resulttype=core&format=json

The uncompetitive NMDA receptor antagonists ketamine and memantine preferentially increase the choice for a small, immediate reward in low-impulsive rats

25 February 2020

cites work

1 reference

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Antagonism of sigma-1 receptors blocks compulsive-like eating

29 September 2017

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New pharmacological treatment strategies for relapse prevention

29 September 2017

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GluN2B subunit deletion reveals key role in acute and chronic ethanol sensitivity of glutamate synapses in bed nucleus of the stria terminalis.

29 September 2017

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New advances in NMDA receptor pharmacology

29 September 2017

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Fighting neurodegeneration with rapamycin: mechanistic insights

29 September 2017

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Activation of σ-receptors induces binge-like drinking in Sardinian alcohol-preferring rats

29 September 2017

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Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders

29 September 2017

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Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

29 September 2017

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mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists

29 September 2017

1 reference

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Memantine preferentially blocks extrasynaptic over synaptic NMDA receptor currents in hippocampal autapses

29 September 2017

1 reference

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Glutamate receptor ion channels: structure, regulation, and function

29 September 2017

1 reference

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Phosphorylation regulates removal of synaptic N-methyl-D-aspartate receptors after withdrawal from chronic ethanol exposure

29 September 2017

1 reference

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Dissecting the role of mTOR: lessons from mTOR inhibitors

29 September 2017

1 reference

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mTOR signaling: at the crossroads of plasticity, memory and disease

29 September 2017

1 reference

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Memantine binding to a superficial site on NMDA receptors contributes to partial trapping

29 September 2017

1 reference

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Differential effects of chronic ethanol consumption and withdrawal on homer/glutamate receptor expression in subregions of the accumbens and amygdala of P rats

29 September 2017

1 reference

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Alcohol exposure alters NMDAR function in the bed nucleus of the stria terminalis

29 September 2017

1 reference

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Critical role for hypothalamic mTOR activity in energy balance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

mTOR-dependent signalling in Alzheimer's disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

The sigma-receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking

29 September 2017

1 reference

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Glutamatergic substrates of drug addiction and alcoholism

29 September 2017

1 reference

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When administered into the nucleus accumbens core or shell, the NMDA receptor antagonist AP-5 reinstates cocaine-seeking behavior in the rat.

29 September 2017

1 reference

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The growing role of mTOR in neuronal development and plasticity.

29 September 2017

1 reference

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Enhancement of long-term spatial memory in adult rats by the noncompetitive NMDA receptor antagonists, memantine and neramexane

29 September 2017

1 reference

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Mechanism of action of memantine

29 September 2017

1 reference

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Neuroprotective and abstinence-promoting effects of acamprosate: elucidating the mechanism of action

29 September 2017

1 reference

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Altered NMDA glutamate receptor antagonist response in individuals with a family vulnerability to alcoholism

29 September 2017

1 reference

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NMDA receptors in alcoholism

29 September 2017

1 reference

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N-methyl-D-aspartate glutamate receptors and alcoholism: reward, dependence, treatment, and vulnerability

29 September 2017

1 reference

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A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus

29 September 2017

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Treatment of alcohol-dependent outpatients with acamprosate: a clinical review

29 September 2017

1 reference

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The anti-craving compound acamprosate acts as a weak NMDA-receptor antagonist, but modulates NMDA-receptor subunit expression similar to memantine and MK-801.

29 September 2017

1 reference

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The relationships of a family history of alcohol dependence, a low level of response to alcohol and six domains of life functioning to the development of alcohol use disorders.

29 September 2017

1 reference

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Effects of a novel uncompetitive NMDA receptor antagonist, MRZ 2/579 on ethanol self-administration and ethanol withdrawal seizures in the rat.

29 September 2017

1 reference

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The NMDA receptor partial agonist, 1-aminocyclopropanecarboxylic acid (ACPC), reduces ethanol consumption in the rat.

29 September 2017

1 reference

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Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist--a review of preclinical data

29 September 2017

1 reference

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Animal models of alcoholism: neurobiology of high alcohol-drinking behavior in rodents

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Genetic and environmental contributions to alcohol abuse and dependence in a population-based sample of male twins

29 September 2017

1 reference

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Pharmacogenetic models of alcoholism.

29 September 2017

1 reference

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Cellular and behavioral neurobiology of alcohol: receptor-mediated neuronal processes.

29 September 2017

1 reference

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An 8-year follow-up of 450 sons of alcoholic and control subjects

29 September 2017

1 reference

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From controlled drug intake to loss of control: the irreversible development of drug addiction in the rat.

29 September 2017

1 reference

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Low level of response to alcohol as a predictor of future alcoholism

29 September 2017

1 reference

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Prospects for clinically tolerated NMDA antagonists: open-channel blockers and alternative redox states of nitric oxide

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Ethanol and the NMDA receptor

29 September 2017

1 reference

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NMDA receptors in mice bred to be prone or resistant to ethanol withdrawal seizures

29 September 2017

1 reference

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Anti-craving compounds for ethanol: new pharmacological tools to study addictive processes

29 September 2017

1 reference

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An increase in basal BDNF provokes hyperactivation of the Akt-mammalian target of rapamycin pathway and deregulation of local dendritic translation in a mouse model of Down's syndrome.

29 September 2017

1 reference

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Differences in degree of trapping of low-affinity uncompetitive N-methyl-D-aspartic acid receptor antagonists with similar kinetics of block.

27 June 2018

1 reference

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Ethanol reward and aversion in mice bred for sensitivity to ethanol withdrawal.

27 June 2018

1 reference

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ESBRA-Nordmann 1996 Award Lecture: ethanol drinking behaviour in Sardinian alcohol-preferring rats.

27 June 2018

1 reference

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Aminoadamantanes as NMDA receptor antagonists and antiparkinsonian agents--preclinical studies.

27 June 2018

1 reference

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In vivo studies on the effects of memantine on dopamine metabolism in the striatum and n. accumbens of the rat.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Replication of the Stockholm Adoption Study of alcoholism. Confirmatory cross-fostering analysis.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Effects of competitive N-methyl-d-aspartate antagonists on midbrain dopamine neurons: An electrophysiological and behavioral comparison to phencyclidine

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Electrophysiological effects of MK-801 on rat nigrostriatal and mesoaccumbal dopaminergic neurons

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Oral ethanol self-administration in rats is reduced by the administration of dopamine and glutamate receptor antagonists into the nucleus accumbens

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Differential behavioural and neurochemical effects of competitive and non-competitive NMDA receptor antagonists in rats

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Effects of the non-competitive NMDA receptor antagonist memantine on the volitional consumption of ethanol by alcohol-preferring rats

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Alcohol withdrawal-induced hippocampal neurotoxicity in vitro and seizures in vivo are both reduced by memantine

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Determination of amino acid levels in the rat striatum, after administration of ethanol alone and associated with ketamine, a glutamatergic antagonist

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Antiglutamatergic strategies for ethanol detoxification: comparison with placebo and diazepam.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Effect of memantine on cue-induced alcohol craving in recovering alcohol-dependent patients.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Dissociation between opioid and CRF1 antagonist sensitive drinking in Sardinian alcohol-preferring rats.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Effects of NMDA glutamate receptor antagonist drugs on the volitional consumption of ethanol by a genetic drinking rat.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

The role of NMDA receptor binding sites in ethanol place conditioning

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Acute and chronic ethanol alter glutamatergic transmission in rat central amygdala: an in vitro and in vivo analysis.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Effects of memantine, an NMDA receptor antagonist, on place preference conditioned with drug and nondrug reinforcers in mice

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Characterization of the discriminative stimulus effects of N-methyl- D-aspartate ligands under different ethanol training conditions in the cynomolgus monkey ( Macaca fascicularis).

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Attenuation of ketamine effects by nimodipine pretreatment in recovering ethanol dependent men: psychopharmacologic implications of the interaction of NMDA and L-type calcium channel antagonists

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Memantine, but not dizocilpine, ameliorates cognitive deficits in adult rats withdrawn from chronic ingestion of alcohol

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

N-methyl-D-aspartate receptor responses are differentially modulated by noncompetitive receptor antagonists and ethanol in inbred long-sleep and short-sleep mice: behavior and electrophysiology.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Memantine and ACPC affect conditioned place preference induced by cocaine in rats.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Effects of dizocilpine (MK 801) on noradrenaline, serotonin and dopamine release and uptake.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Blockade of the acquisition of ethanol-induced conditioned place preference by N-methyl-D-aspartate receptor antagonists.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

MK-801 reinstates drug-seeking behaviour in cocaine-trained rats.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

The NMDA antagonist, dizocilpine, enhances cocaine reinforcement without influencing mesoaccumbens dopamine transmission.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Discriminative stimulus effects of ethanol: effect of training dose on the substitution of N-methyl-D-aspartate antagonists.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Effects of dizocilpine in withdrawal seizure-prone (WSP) and withdrawal seizure-resistant (WSR) mice.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Effects of MK 801 and diazepam on the EEG of P and NP rats.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646912

Study on the role of glycine, strychnine-insensitive receptors (glycineB sites) in the discriminative stimulus effects of ethanol in the rat

5 September 2018

1 reference

12 December 2020

Ethanol-like discriminative stimulus effects of non-competitive n-methyl-d-aspartate antagonists

1 reference

12 December 2020

Ethanol-reinforced behaviour in the rat: effects of uncompetitive NMDA receptor antagonist, memantine

1 reference

12 December 2020

Ethanol inhibits NMDA-activated ion current in hippocampal neurons

1 reference

12 December 2020

Trapping channel block of NMDA-activated responses by amantadine and memantine

1 reference

12 December 2020

Evidence for alcohol anti-craving properties of memantine

1 reference

12 December 2020

On the roles of dopamine D-1 vs. D-2 receptors for the hyperactivity response elicited by MK-801

1 reference

12 December 2020

Ethanol and N -methyl- D -aspartate receptor complex interactions: a detailed drug discrimination study in the rat

1 reference

12 December 2020

Inheritance of alcohol abuse. Cross-fostering analysis of adopted men

1 reference

12 December 2020

10.1016/J.BBR.2013.02.030

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23466691%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23466691%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

PubMed publication ID

23466691

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23466691%20AND%20SRC:MED&resulttype=core&format=json