(Q36824250)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18485433%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Arsenite-induced mitotic death involves stress response and is independent of tubulin polymerization (English)

1 reference

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7 January 2020

4

1 reference

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7 January 2020

author name string

B Frazier Taylor

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18485433%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Samuel C McNeely

series ordinal

2

1 reference

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7 January 2020

Heather L Miller

series ordinal

3

1 reference

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7 January 2020

publication date

14 March 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18485433%20AND%20SRC:MED&resulttype=core&format=json

Toxicology and Applied Pharmacology

7 January 2020

published in

1 reference

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7 January 2020

volume

230

1 reference

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7 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18485433%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

page(s)

235-246

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describes a project that uses

7 January 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2504415/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Sensitivity to sodium arsenite in human melanoma cells depends upon susceptibility to arsenite-induced mitotic arrest.

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Exit from arsenite-induced mitotic arrest is p53 dependent

29 September 2017

1 reference

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Arsenite and monomethylarsonous acid generate oxidative stress response in human bladder cell culture

29 September 2017

1 reference

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p53 suppression of arsenite-induced mitotic catastrophe is mediated by p21CIP1/WAF1.

29 September 2017

1 reference

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17-AAG, an Hsp90 inhibitor, causes kinetochore defects: a novel mechanism by which 17-AAG inhibits cell proliferation

29 September 2017

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Dynamic regulation and involvement of the heat shock transcriptional response in arsenic carcinogenesis

29 September 2017

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Hsp70 protects mitotic cells against heat-induced centrosome damage and division abnormalities

29 September 2017

1 reference

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Phase I pharmacokinetic-pharmacodynamic study of 17-(allylamino)-17-demethoxygeldanamycin (17AAG, NSC 330507), a novel inhibitor of heat shock protein 90, in patients with refractory advanced cancers

29 September 2017

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Use of arsenic trioxide in haematological malignancies: insight into the clinical development of a novel agent

29 September 2017

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Arsenite delays progression through each cell cycle phase and induces apoptosis following G2/M arrest in U937 myeloid leukemia cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Arsenite induces prominent mitotic arrest via inhibition of G2 checkpoint activation in CGL-2 cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Geldanamycin induces mitotic catastrophe and subsequent apoptosis in human glioma cells

29 September 2017

1 reference

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Experimental and theoretical characterization of arsenite in water: insights into the coordination environment of As-O.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia

29 September 2017

1 reference

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Combined treatment with arsenic trioxide and all-trans-retinoic acid in patients with relapsed acute promyelocytic leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Taxanes: microtubule and centrosome targets, and cell cycle dependent mechanisms of action

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

EB1 targets to kinetochores with attached, polymerizing microtubules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

The assembly and intermolecular properties of the hsp70-Hop-hsp90 molecular chaperone complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Involvement of microtubules and mitochondria in the antagonism of arsenic trioxide on paclitaxel-induced apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Arsenite disrupts mitosis and induces apoptosis in SV40-transformed human skin fibroblasts.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

A constitutive 70 kDa heat-shock protein is localized on the fibres of spindles and asters at metaphase in an ATP-dependent manner: a new chaperone role is proposed

29 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

29 September 2017

12 December 2020

Requirement of Hsp90 for centrosomal function reflects its regulation of Polo kinase stability

1 reference

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29 September 2017

1 reference

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Clinical trials of arsenic trioxide in hematologic and solid tumors: overview of the National Cancer Institute Cooperative Research and Development Studies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

History of the development of arsenic derivatives in cancer therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Introduction: the history of arsenic trioxide in cancer therapy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Drug approval summaries: arsenic trioxide, tamoxifen citrate, anastrazole, paclitaxel, bexarotene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Sensitivity of myelomonocytic leukemia cells to arsenite-induced cell cycle disruption, apoptosis, and enhanced differentiation is dependent on the inter-relationship between arsenic concentration, duration of treatment, and cell cycle phase.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

A novel one-step, highly sensitive fluorometric assay to evaluate cell-mediated cytotoxicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Arsenite inhibits mitotic division and perturbs spindle dynamics in HeLa S3 cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Molecular chaperones and the cytoskeleton

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Bcl-2 phosphorylation required for anti-apoptosis function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Pharmacokinetic study of paclitaxel in malignant ascites from advanced gastric cancer patients

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Disruption of microtubule assembly and spindle formation as a mechanism for the induction of aneuploid cells by sodium arsenite and vanadium pentoxide.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Nucleated assembly of mitotic microtubules in living PTK2 cells after release from nocodazole treatment.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

hsp70 is localized to the centrosome of dividing HeLa cells

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Effects of sodium arsenite on the cytoskeleton and cellular glutathione levels in cultured cells

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

A phase II trial of 17-(Allylamino)-17-demethoxygeldanamycin in patients with papillary and clear cell renal cell carcinoma

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Induction of centrosome amplification during arsenite-induced mitotic arrest in CGL-2 cells.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Oxidation and methylation status determine the effects of arsenic on the mitotic apparatus

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Low concentrations of taxol cause mitotic delay followed by premature dissociation of p55CDC from Mad2 and BubR1 and abrogation of the spindle checkpoint, leading to aneuploidy

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Arsenic trioxide uptake by human and rat aquaglyceroporins

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Arsenic trioxide arrests cells early in mitosis leading to apoptosis

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Arsenic trioxide produces polymerization of microtubules and mitotic arrest before apoptosis in human tumor cell lines

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

The effect of different doses of cyclosporin A on the systemic exposure of orally administered paclitaxel

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Mechanisms of Taxol-induced cell death are concentration dependent.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Heat shock alters centrosome organization leading to mitotic dysfunction and cell death

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504415

Effects of heat shock protein 70 (Hsp70) on arsenite-induced genotoxicity

5 September 2018

1 reference

12 December 2020

Cooperative action of Hsp70, Hsp90, and DnaJ proteins in protein renaturation

1 reference

12 December 2020

17-dimethylaminoethylamino-17-demethoxygeldanamycin in patients with advanced-stage solid tumors and lymphoma: a phase I study

1 reference

12 December 2020

PAC fixed dose: pharmacokinetics of a 1-hour paclitaxel infusion and comparison to BSA-normalized drug dosing

1 reference

12 December 2020

A phase I trial of twice-weekly 17-allylamino-demethoxy-geldanamycin in patients with advanced cancer

1 reference

12 December 2020

Chinese folk treatment reveals power of arsenic to treat cancer, new studies under way

1 reference

12 December 2020

Microtubule disassembly delays the G2-M transition in vertebrates

1 reference

12 December 2020

Phase II study of 3-hour infusion of paclitaxel in previously untreated non-small cell lung cancer

1 reference

12 December 2020

Arsenic targets tubulins to induce apoptosis in myeloid leukemia cells

1 reference

12 December 2020

Constitutive hsp70 Is Essential to Mitosis during Early Cleavage of Paracentrotus lividus Embryos: The Blockage of Constitutive hsp70 Impairs Mitosis

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of 17-demethoxy 17-[[(2-dimethylamino)ethyl]amino]geldanamycin (17DMAG, NSC 707545) in C.B-17 SCID mice bearing MDA-MB-231 human breast cancer xenografts

1 reference

12 December 2020

10.1016/J.TAAP.2008.02.030

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18485433%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18485433%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PubMed publication ID

18485433

1 reference