(Q36825024)

English

Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness

scientific article published on 14 October 2005

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scholarly article

1 reference

Europe PubMed Central

16 August 2017

Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness (English)

1 reference

Europe PubMed Central

16 August 2017

Krzysztof Palczewski

10

object named as

Krzysztof Palczewski

1 reference

Europe PubMed Central

16 August 2017

William W Hauswirth

11

object named as

William W Hauswirth

1 reference

Europe PubMed Central

16 August 2017

Artur V Cideciyan

5

object named as

Artur V Cideciyan

1 reference

Europe PubMed Central

16 August 2017

Gregory M Acland

1

object named as

Gregory M Acland

1 reference

Europe PubMed Central

16 August 2017

author name string

Gustavo D Aguirre

2

1 reference

Europe PubMed Central

16 August 2017

Jean Bennett

3

1 reference

Europe PubMed Central

16 August 2017

Tomas S Aleman

4

1 reference

Europe PubMed Central

16 August 2017

Jeannette Bennicelli

6

1 reference

Europe PubMed Central

16 August 2017

Nadine S Dejneka

7

1 reference

Europe PubMed Central

16 August 2017

Susan E Pearce-Kelling

8

1 reference

Europe PubMed Central

16 August 2017

Albert M Maguire

9

1 reference

Europe PubMed Central

16 August 2017

Samuel G Jacobson

12

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Europe PubMed Central

16 August 2017

publication date

14 October 2005

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Europe PubMed Central

16 August 2017

Molecular Therapy

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Europe PubMed Central

16 August 2017

12

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Europe PubMed Central

16 August 2017

6

1 reference

Europe PubMed Central

16 August 2017

1072-1082

1 reference

Europe PubMed Central

16 August 2017

Identifying photoreceptors in blind eyes caused by RPE65 mutations: Prerequisite for human gene therapy success

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

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Recent advances in early-onset severe retinal degeneration: more than just basic research

1 reference

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29 September 2017

Leber congenital amaurosis: comprehensive survey of the genetic heterogeneity, refinement of the clinical definition, and genotype-phenotype correlations as a strategy for molecular diagnosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

29 September 2017

Isorhodopsin rather than rhodopsin mediates rod function in RPE65 knock-out mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

29 September 2017

Vitamin A metabolism in the retinal pigment epithelium: genes, mutations, and diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

29 September 2017

In vivo gene therapy in young and adult RPE65-/- dogs produces long-term visual improvement.

1 reference

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Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

29 September 2017

Molecular genetics of Leber congenital amaurosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

29 September 2017

Naturally occurring rhodopsin mutation in the dog causes retinal dysfunction and degeneration mimicking human dominant retinitis pigmentosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

29 September 2017

Recovery of visual functions in a mouse model of Leber congenital amaurosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

29 September 2017

Confronting complexity: the interlink of phototransduction and retinoid metabolism in the vertebrate retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

29 September 2017

Rapid restoration of visual pigment and function with oral retinoid in a mouse model of childhood blindness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

29 September 2017

Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated gene transfer to monkey retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

29 September 2017

Retinal dystrophy of Swedish briard/briard-beagle dogs is due to a 4-bp deletion in RPE65.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

29 September 2017

Neonatal gene transfer leads to widespread correction of pathology in a murine model of lysosomal storage disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

29 September 2017

Congenital stationary night blindness in the dog: common mutation in the RPE65 gene indicates founder effect.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

29 September 2017

Rod and cone specific domains in the interphotoreceptor matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

29 September 2017

Different RPGR exon ORF15 mutations in Canids provide insights into photoreceptor cell degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

27 June 2018

Postsurgical assessment and long-term safety of recombinant adeno-associated virus-mediated gene transfer into the retinas of dogs and primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

5 September 2018

Retinal degeneration 12 (rd12): a new, spontaneously arising mouse model for human Leber congenital amaurosis (LCA).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

5 September 2018

Quantifying rod photoreceptor-mediated vision in retinal degenerations: dark-adapted thresholds as outcome measures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

5 September 2018

In utero gene therapy rescues vision in a murine model of congenital blindness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

5 September 2018

The retinoid cycle and retina disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

5 September 2018

Recovery of the human photopic electroretinogram after bleaching exposures: estimation of pigment regeneration kinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

5 September 2018

Gene transfer in the RPE65 null mutation dog: relationship between construct volume, visual behavior and electroretinographic (ERG) results

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

5 September 2018

Functional and structural recovery of the retina after gene therapy in the RPE65 null mutation dog.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

5 September 2018

Rod and cone contributions to the a-wave of the electroretinogram of the macaque

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

5 September 2018

Retinal degeneration and RPE transplantation in Rpe65(-/-) mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

5 September 2018

Gene therapy restores vision in a canine model of childhood blindness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

5 September 2018

Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

5 September 2018

Persistent transgene product in retina, optic nerve and brain after intraocular injection of rAAV.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

5 September 2018

Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

5 September 2018

An alternative phototransduction model for human rod and cone ERG a-waves: normal parameters and variation with age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3647373

5 September 2018

Rhodopsin levels in the central retinas of normal miniature poodles and those with progressive rod-cone degeneration

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.008

7 January 2021

Retinal degenerations in the dog: IV. Early retinal degeneration (erd) in Norwegian elkhounds

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.008

7 January 2021

Anti-rhodopsin monoclonal antibodies of defined specificity: characterization and application

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2005.08.008

7 January 2021

Identifiers

10.1016/J.YMTHE.2005.08.008

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

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