(Q36826030)

16 August 2017

Design and synthesis of phosphotyrosine peptidomimetic prodrugs (English)

1 reference

16 August 2017

Hugo Garrido-Hernandez

1

1 reference

16 August 2017

Kyung D Moon

2

1 reference

16 August 2017

Robert L Geahlen

3

1 reference

16 August 2017

Richard F Borch

4

1 reference

16 August 2017

language of work or name

English

0 references

publication date

1 June 2006

1 reference

Journal of Medicinal Chemistry

16 August 2017

1 reference

16 August 2017

49

1 reference

16 August 2017

11

1 reference

16 August 2017

3368-3376

1 reference

Synthesis and biological evaluation of a cytarabine phosphoramidate prodrug

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2505179

Synthesis and biological studies of novel nucleoside phosphoramidate prodrugs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2505179

Synthesis and evaluation of pteroic acid-conjugated nitroheterocyclic phosphoramidates as folate receptor-targeted alkylating agents

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2505179

Activation mechanisms of nucleoside phosphoramidate prodrugs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2505179

Synthesis and biological activity of novel 5-fluoro-2'-deoxyuridine phosphoramidate prodrugs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2505179

SH2-directed ligands of the Lck tyrosine kinase.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2505179

SH2 domain protein interaction and possibilities for pharmacological intervention

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2505179

SH2 domain function is essential for the role of the Lck tyrosine kinase in T cell receptor signal transduction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2505179

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2505179

SH2 domains recognize specific phosphopeptide sequences

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2505179

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2505179

Involvement of pp60c-src with two major signaling pathways in human breast cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2505179

Activation of the pp60c-src protein kinase is an early event in colonic carcinogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2505179

SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2505179

Inhibition of SH2 domain/phosphoprotein association by a nonhydrolyzable phosphonopeptide

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2505179

Characterization of protein tyrosine kinases from human breast cancer: involvement of the c-src oncogene product.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2505179

Rosmarinic acid inhibits TCR-induced T cell activation and proliferation in an Lck-dependent manner

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2505179

Nonpeptidic, monocharged, cell permeable ligands for the p56lck SH2 domain.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2505179

X-Ray structure of citrate bound to Src SH2 leads to a high-affinity, bone-targeted Src SH2 inhibitor

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2505179

The Lck SH2 phosphotyrosine binding site is critical for efficient TCR-induced processive tyrosine phosphorylation of the zeta-chain and IL-2 production

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2505179

Ligands for the Tyrosine Kinase p56lckSH2 Domain: Discovery of Potent Dipeptide Derivatives with Monocharged, Nonhydrolyzable Phosphate Replacements

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2505179

Protonation of phosphoramide mustard and other phosphoramides

4 December 2018

1 reference

12 December 2020

Comparison of the protonation of isophosphoramide mustard and phosphoramide mustard

1 reference

12 December 2020

Synthesis and Biological Evaluation of 5-Fluoro-2'-deoxyuridine Phosphoramidate Analogs

1 reference

12 December 2020

Src homology-2 domains: structure, mechanisms, and drug discovery

1 reference

12 December 2020

Design and synthesis of a pyridone-based phosphotyrosine mimetic

1 reference

12 December 2020

Identifiers

DOI

10.1021/JM060142P

1 reference

16 August 2017

1 reference

16 August 2017

PubMed publication ID

16722656

1 reference