(Q36831801)

16 August 2017

Endothelial Notch1 Is Required for Proper Development of the Semilunar Valves and Cardiac Outflow Tract (English)

1 reference

Nitric oxide synthase 3, endothelial cell

16 August 2017

0 references

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Sara N Koenig

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27107132%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Freddy Radtke

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27107132%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Vidu Garg

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27107132%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Kevin Bosse

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27107132%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Uddalak Majumdar

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27107132%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Elizabeth M Bonachea

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27107132%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

language of work or name

1 reference

22 April 2016

1 reference

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

16 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27107132%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27107132%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27107132%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

4 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4843530/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Targeted next-generation sequencing identifies pathogenic variants in familial congenital heart disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Aortic dilatation in patients with bicuspid aortic valve.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Endothelial nitric oxide signaling regulates Notch1 in aortic valve disease.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Insufficient versican cleavage and Smad2 phosphorylation results in bicuspid aortic and pulmonary valves

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Deficient signaling via Alk2 (Acvr1) leads to bicuspid aortic valve development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Coordinating tissue interactions: Notch signaling in cardiac development and disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Loss of Gata5 in mice leads to bicuspid aortic valve

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Calcific aortic valve stenosis: methods, models, and mechanisms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Cardiac neural crest orchestrates remodeling and functional maturation of mouse semilunar valves

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Notch Signaling in the Vasculature

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

De novo copy number variants identify new genes and loci in isolated sporadic tetralogy of Fallot

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Murine Jagged1/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue-tissue interactions during outflow tract development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

The canonical Notch signaling pathway: unfolding the activation mechanism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

NOTCH1 mutations in individuals with left ventricular outflow tract malformations reduce ligand-induced signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Bicuspid aortic valve: clinical approach and scientific review of a common clinical entity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

A global double-fluorescent Cre reporter mouse

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Mutations in NOTCH1 cause aortic valve disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Cardiac outflow tract defects in mice lacking ALK2 in neural crest cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

The incidence of congenital heart disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Fate of the mammalian cardiac neural crest

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Neural crest cells contribute to normal aorticopulmonary septation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Compound heterozygous NOTCH1 mutations underlie impaired cardiogenesis in a patient with hypoplastic left heart syndrome.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Rare GATA5 sequence variants identified in individuals with bicuspid aortic valve

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Neural crest cells are required for correct positioning of the developing outflow cushions and pattern the arterial valve leaflets

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

A mechanism for gene-environment interaction in the etiology of congenital scoliosis.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Genetically alike Syrian hamsters display both bifoliate and trifoliate aortic valves.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

GATA5 interacts with GATA4 and GATA6 in outflow tract development

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Bicuspid aortic valves with different spatial orientations of the leaflets are distinct etiological entities.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Neural crest cells retain multipotential characteristics in the developing valves and label the cardiac conduction system.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

The right ventricle, outflow tract, and ventricular septum comprise a restricted expression domain within the secondary/anterior heart field

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

The outflow tract of the heart is recruited from a novel heart-forming field

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4843530

Conotruncal myocardium arises from a secondary heart field

5 September 2018

1 reference

12 December 2020

The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm

1 reference

12 December 2020

Burden of valvular heart diseases: a population-based study

1 reference

12 December 2020

Genetic contribution of bicuspid aortic valve morphology

1 reference

12 December 2020

Ranolazine: A Contemporary Review

1 reference

12 December 2020

Embryonic Development of the Bicuspid Aortic Valve

1 reference

12 December 2020

Pax3 is required for cardiac neural crest migration in the mouse: evidence from the splotch (Sp2H) mutant

1 reference

12 December 2020

Identifiers

DOI

10.1161/JAHA.115.003075

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27107132%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27107132%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

PubMed publication ID

27107132

1 reference