(Q36835706)

16 August 2017

Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer (English)

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16 August 2017

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14

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16 August 2017

19

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16 August 2017

Ana-Teresa Maia

8

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Paul D P Pharoah

18

object named as

Paul D P Pharoah

1 reference

16 August 2017

Adele Murrell

22

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Thibaud Koessler

2

object named as

Thibaud Koessler

1 reference

16 August 2017

17

Sheila Bingham

1 reference

16 August 2017

Yoko Ito

1

1 reference

16 August 2017

Ashraf E K Ibrahim

3

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16 August 2017

Sushma Rai

4

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16 August 2017

Sarah L Vowler

5

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16 August 2017

Sayeda Abu-Amero

6

1 reference

16 August 2017

Ana-Luisa Silva

7

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16 August 2017

Joanna E Huddleston

9

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16 August 2017

Santiago Uribe-Lewis

10

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16 August 2017

Kathryn Woodfine

11

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16 August 2017

Maja Jagodic

12

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16 August 2017

Raffaella Nativio

13

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16 August 2017

Gudrun Moore

15

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16 August 2017

Elena Klenova

16

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16 August 2017

Stephan Beck

20

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16 August 2017

Manjinder S Sandhu

21

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16 August 2017

9 June 2008

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16 August 2017

Human Molecular Genetics

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16 August 2017

17

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16 August 2017

17

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16 August 2017

2633-2643

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Distinct methylation changes at the IGF2-H19 locus in congenital growth disorders and cancer.

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Highly methylated genes in colorectal neoplasia: implications for screening

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Loss of imprinting in IGF2 in colorectal carcinoma assessed by microdissection.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Loss of imprinting of IGF2: a common epigenetic modifier of intestinal tumor risk

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Polymorphisms in the initiators of RET (rearranged during transfection) signaling pathway and susceptibility to sporadic medullary thyroid carcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Gene expression studies provide clues to the pathogenesis of uterine leiomyoma: new evidence and a systematic review

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Allele-specific methylation analysis on upstream promoter region of H19 by methylation-specific PCR with confronting two-pair primers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Genomic imprinting: CTCF protects the boundaries

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Sensitive and quantitative universal Pyrosequencing methylation analysis of CpG sites

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Distinct transcriptional profiles of adrenocortical tumors uncovered by DNA microarray analysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Tumor development in the Beckwith-Wiedemann syndrome is associated with a variety of constitutional molecular 11p15 alterations including imprinting defects of KCNQ1OT1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

An intragenic methylated region in the imprinted Igf2 gene augments transcription.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Genomic imprinting: parental influence on the genome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Igf2 imprinting in development and disease.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Abnormal RNA expression of 11p15 imprinted genes and kidney developmental genes in Wilms' tumor.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Loss of imprinting of IGF2 and not H19 in breast cancer, adjacent normal tissue and derived fibroblast cultures

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Biallelic expression of the H19 and IGF2 genes in hepatocellular carcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Multiple imprinted sense and antisense transcripts, differential methylation and tandem repeats in a putative imprinting control region upstream of mouse Igf2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Randomised controlled trial of faecal-occult-blood screening for colorectal cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Randomised study of screening for colorectal cancer with faecal-occult-blood test

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer Linkage Consortium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Examination of IGF2 and H19 loss of imprinting in bladder cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

LOI of IGF2 is associated with esophageal cancer and linked to methylation status of IGF2 DMR.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Analysis of gene-specific DNA methylation patterns by pyrosequencing technology.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Imprinting of IGF2 P0 transcript and novel alternatively spliced INS-IGF2 isoforms show differences between mouse and human.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Detection in fecal DNA of colon cancer-specific methylation of the nonexpressed vimentin gene.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Loss of imprinting of insulin growth factor II gene: a potential heritable biomarker for colon neoplasia predisposition.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Loss of insulin-like growth factor-II imprinting and the presence of screen-detected colorectal adenomas in women

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Epigenetic modifications in an imprinting cluster are controlled by a hierarchy of DMRs suggesting long-range chromatin interactions.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Deletion of a silencer element in Igf2 results in loss of imprinting independent of H19.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Maternal-specific footprints at putative CTCF sites in the H19 imprinting control region give evidence for insulator function.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Relaxation of IGF2 imprinting in Wilms tumours associated with specific changes in IGF2 methylation

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Frequent loss of imprinting of the H19 and IGF-II genes in ovarian tumors.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

EPIC-Norfolk: study design and characteristics of the cohort. European Prospective Investigation of Cancer

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Molecular subtypes and phenotypic expression of Beckwith–Wiedemann syndrome

20 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515372

Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive

4 December 2018

1 reference

12 December 2020

Frequent IGF2/H19 domain epigenetic alterations and elevated IGF2 expression in epithelial ovarian cancer

1 reference

12 December 2020

Clinicopathological characteristics of colorectal cancers with loss of imprinting of insulin-like growth factor 2

1 reference

12 December 2020

Improved marker combination for detection of de novo genetic variation and aberrant DNA in colorectal neoplasia

1 reference

12 December 2020

Heritable rather than age-related environmental and stochastic factors dominate variation in DNA methylation of the human IGF2/H19 locus

1 reference

12 December 2020

Loss of imprinting of insulin-like growth factor II is associated with increased risk of proximal colon cancer

1 reference

12 December 2020

Epigenetic heterogeneity at imprinted loci in normal populations

1 reference

12 December 2020

Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2

1 reference

12 December 2020

Loss of imprinting of IGF2 and H19 in osteosarcoma is accompanied by reciprocal methylation changes of a CTCF-binding site

1 reference

12 December 2020

Loss of IGF2 imprinting: a potential marker of colorectal cancer risk

1 reference

12 December 2020

Familial aggregation of abnormal methylation of parental alleles at the IGF2/H19 and IGF2R differentially methylated regions

1 reference

12 December 2020

Aging and DNA methylation in colorectal mucosa and cancer

1 reference

12 December 2020

Screening for genomic fragments that are methylated specifically in colorectal carcinoma with a methylated MLH1 promoter

1 reference

12 December 2020

Identifiers

DOI

10.1093/HMG/DDN163

1 reference

16 August 2017

1 reference

16 August 2017

PubMed publication ID

18541649

1 reference