(Q36835873)

16 August 2017

Inhibitor recognition specificity of MERS-CoV papain-like protease may differ from that of SARS-CoV (English)

1 reference

Middle East respiratory syndrome coronavirus

16 August 2017

0 references

0 references

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25746232%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Amy J Rice

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25746232%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

author name string

Hyun Lee

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25746232%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Hao Lei

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25746232%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Bernard D Santarsiero

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25746232%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Shuyi Cao

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25746232%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Kavankumar Patel

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25746232%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Michael Z Szypulinski

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25746232%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Isabel Ojeda

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25746232%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Arun K Ghosh

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25746232%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Michael E Johnson

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25746232%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

publication date

16 March 2015

1 reference

16 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25746232%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25746232%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

page(s)

1456-1465

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25746232%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25746232%20AND%20SRC:MED&resulttype=core&format=json

Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression

5 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

Crystal structure of the papain-like protease of MERS coronavirus reveals unusual, potentially druggable active-site features

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating Activity of SARS-CoV Papain-Like Protease

29 September 2017

1 reference

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X-ray Structural and Biological Evaluation of a Series of Potent and Highly Selective Inhibitors of Human Coronavirus Papain-like Proteases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

Structural basis for catalysis and ubiquitin recognition by the severe acute respiratory syndrome coronavirus papain-like protease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

MERS-CoV papain-like protease has deISGylating and deubiquitinating activities

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

Proteolytic processing, deubiquitinase and interferon antagonist activities of Middle East respiratory syndrome coronavirus papain-like protease

29 September 2017

1 reference

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Identification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screenings

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

Synergistic inhibitor binding to the papain-like protease of human SARS coronavirus: mechanistic and inhibitor design implications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

Hospital outbreak of Middle East respiratory syndrome coronavirus

29 September 2017

1 reference

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Clinical features and viral diagnosis of two cases of infection with Middle East Respiratory Syndrome coronavirus: a report of nosocomial transmission

29 September 2017

1 reference

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29 September 2017

1 reference

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Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group

29 September 2017

1 reference

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A novel coronavirus capable of lethal human infections: an emerging picture

29 September 2017

1 reference

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Human coronavirus EMC does not require the SARS-coronavirus receptor and maintains broad replicative capability in mammalian cell lines

29 September 2017

1 reference

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Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans

29 September 2017

1 reference

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Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia

29 September 2017

1 reference

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Is the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic?

29 September 2017

1 reference

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Severe Acute Respiratory Syndrome Coronavirus Papain-like Novel Protease Inhibitors: Design, Synthesis, Protein−Ligand X-ray Structure and Biological Evaluation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

Features and development of Coot

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

Structure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome-coronavirus papain-like protease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

Phasercrystallographic software

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

Drug design targeting the main protease, the Achilles' heel of coronaviruses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzyme

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

The papain-like protease of severe acute respiratory syndrome coronavirus has deubiquitinating activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

Bats are natural reservoirs of SARS-like coronaviruses

29 September 2017

1 reference

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Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats

29 September 2017

1 reference

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REFMAC5 dictionary: organization of prior chemical knowledge and guidelines for its use

29 September 2017

1 reference

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Identification of severe acute respiratory syndrome coronavirus replicase products and characterization of papain-like protease activity

29 September 2017

1 reference

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Molecular biology of severe acute respiratory syndrome coronavirus

29 September 2017

1 reference

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Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus

29 September 2017

1 reference

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Mechanisms and enzymes involved in SARS coronavirus genome expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

Crystal structure of a deubiquitinating enzyme (human UCH-L3) at 1.8 A resolution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

Deubiquitination, a new function of the severe acute respiratory syndrome coronavirus papain-like protease?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

First cases of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infections in France, investigations and implications for the prevention of human-to-human transmission, France, May 2013.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

Update: severe respiratory illness associated with a novel coronavirus--worldwide, 2012-2013.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

Pleiotropic effects of Ubp6 loss on drug sensitivities and yeast prion are due to depletion of the free ubiquitin pool

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

Emerging human coronaviruses--disease potential and preparedness

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4845099

Evaluation of enzyme inhibitors in drug discovery. A guide for medicinal chemists and pharmacologists

20 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25746232

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/CB500917M

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25746232%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25746232%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25746232%20AND%20SRC:MED&resulttype=core&format=json