(Q34683256)

English

Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression

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scholarly article

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Europe PubMed Central

PubMed publication ID

3 August 2017

Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Middle East respiratory syndrome coronavirus

0 references

structural biology

Middle East respiratory syndrome coronavirus

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Middle East respiratory syndrome

1 reference

based on heuristic

inferred from title

Puck B van Kasteren

object named as

Puck B van Kasteren

6

0 references

object named as

Brian L Mark

10

0 references

object named as

Eric J Snijder

8

0 references

Marjolein Kikkert

9

object named as

Marjolein Kikkert

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

author name string

Ben A Bailey-Elkin

1

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Robert C M Knaap

2

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Garrett G Johnson

3

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Tim J Dalebout

4

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Dennis K Ninaber

5

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Peter J Bredenbeek

7

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

language of work or name

0 references

publication date

15 October 2014

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

3 August 2017

289

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

50

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

34667-34682

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Catalytic function and substrate specificity of the papain-like protease domain of nsp3 from the Middle East respiratory syndrome coronavirus

1 reference

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1 reference

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7 July 2018

Crystal structure of the papain-like protease of MERS coronavirus reveals unusual, potentially druggable active-site features

1 reference

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Middle East respiratory syndrome coronavirus (MERS-CoV) RNA and neutralising antibodies in milk collected according to local customs from dromedary camels, Qatar, April 2014.

1 reference

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7 July 2018

Structural and functional characterization of MERS coronavirus papain-like protease

1 reference

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Evidence for camel-to-human transmission of MERS coronavirus

1 reference

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Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating Activity of SARS-CoV Papain-Like Protease

1 reference

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Productive replication of Middle East respiratory syndrome coronavirus in monocyte-derived dendritic cells modulates innate immune response.

1 reference

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1 reference

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7 July 2018

Structural basis for catalysis and ubiquitin recognition by the severe acute respiratory syndrome coronavirus papain-like protease

1 reference

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Nidovirus papain-like proteases: multifunctional enzymes with protease, deubiquitinating and deISGylating activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263872

7 July 2018

MERS-CoV papain-like protease has deISGylating and deubiquitinating activities

1 reference

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Proteolytic processing, deubiquitinase and interferon antagonist activities of Middle East respiratory syndrome coronavirus papain-like protease

1 reference

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MEROPS: the database of proteolytic enzymes, their substrates and inhibitors

1 reference

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Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment.

1 reference

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Assessing activity and inhibition of Middle East respiratory syndrome coronavirus papain-like and 3C-like proteases using luciferase-based biosensors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263872

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Regulation of proteolysis by human deubiquitinating enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263872

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The papain-like protease of porcine epidemic diarrhea virus negatively regulates type I interferon pathway by acting as a viral deubiquitinase

1 reference

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1 reference

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7 July 2018

Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells

1 reference

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Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans

1 reference

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Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia

1 reference

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The role of UBL domains in ubiquitin-specific proteases

1 reference

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Non-canonical translation in RNA viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263872

7 July 2018

The ubiquitin code

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263872

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Towards automated crystallographic structure refinement with phenix.refine

1 reference

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1 reference

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1 reference

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1 reference

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Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263872

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Papain-Like Protease 1 from Transmissible Gastroenteritis Virus: Crystal Structure and Enzymatic Activity toward Viral and Cellular Substrates

1 reference

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The cysteine protease domain of porcine reproductive and respiratory syndrome virus nonstructural protein 2 possesses deubiquitinating and interferon antagonism functions

1 reference

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1 reference

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Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases.

1 reference

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The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent

1 reference

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1 reference

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1 reference

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1 reference

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Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I

1 reference

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1 reference

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1 reference

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1 reference

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PLP2, a potent deubiquitinase from murine hepatitis virus, strongly inhibits cellular type I interferon production

1 reference

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1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263872

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The papain-like protease of severe acute respiratory syndrome coronavirus has deubiquitinating activity

1 reference

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21 January 2018

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M114.609644

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

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