(Q39924024)

15 September 2017

PLP2, a potent deubiquitinase from murine hepatitis virus, strongly inhibits cellular type I interferon production (English)

1 reference

15 September 2017

Mouse hepatitis virus

object named as

murine hepatitis virus

1 reference

4

Genhong Cheng

1 reference

15 September 2017

Dahai Zheng

1

1 reference

15 September 2017

Gang Chen

series ordinal

2

1 reference

15 September 2017

Beichu Guo

series ordinal

3

1 reference

15 September 2017

Hong Tang

series ordinal

5

1 reference

15 September 2017

1 November 2008

1 reference

15 September 2017

1 reference

15 September 2017

18

1 reference

15 September 2017

11

1 reference

15 September 2017

1105-1113

1 reference

https://scigraph.springernature.com/pub.10.1038/cr.2008.294

15 September 2017

0 references

cites work

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Cancer metastasis: building a framework

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Genetic determinants of cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Stromal fibroblasts in cancer initiation and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

21 January 2018

Fibroblasts in cancer

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Tumour-educated macrophages promote tumour progression and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Migratory neighbors and distant invaders: tumor-associated niche cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Alterations in components of the TGF-beta superfamily signaling pathways in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Requirement for activin A and transforming growth factor--beta 1 pro-regions in homodimer assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Mapping the domain(s) critical for the binding of human tumor necrosis factor-alpha to its two receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Mechanism of activation of the TGF-beta receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Smad transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

A self-enabling TGFbeta response coupled to stress signaling: Smad engages stress response factor ATF3 for Id1 repression in epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Nucleocytoplasmic shuttling of signal transducers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Specificity and versatility in tgf-beta signaling through Smads

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

C/EBPbeta at the core of the TGFbeta cytostatic response and its evasion in metastatic breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Synexpression groups in eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Genome-wide identification of Smad/Foxh1 targets reveals a role for Foxh1 in retinoic acid regulation and forebrain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Loss of transforming growth factor-beta type II receptor promotes metastatic head-and-neck squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Transforming growth factor beta receptor type II inactivation promotes the establishment and progression of colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Increased Malignancy of Neu-Induced Mammary Tumors Overexpressing Active Transforming Growth Factor β1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

21 January 2018

Focus on pancreas cancer

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Comparative lesion sequencing provides insights into tumor evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

The logic of TGFbeta signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Activin/TGF-beta induce apoptosis through Smad-dependent expression of the lipid phosphatase SHIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Mechanisms of TGF-beta-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Limited overlapping roles of P15(INK4b) and P18(INK4c) cell cycle inhibitors in proliferation and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Immune-mediated eradication of tumors through the blockade of transforming growth factor-beta signaling in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Regulation of the proinflammatory effects of Fas ligand (CD95L).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Immunoregulatory role of transforming growth factor beta (TGF-beta) in development of killer cells: comparison of active and latent TGF-beta 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

A multigenic program mediating breast cancer metastasis to bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Synergistic cooperation between hypoxia and transforming growth factor-beta pathways on human vascular endothelial growth factor gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

TGF-beta signaling in tumor suppression and cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Epithelial-mesenchymal transitions in tumour progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Differentiation plasticity regulated by TGF-beta family proteins in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

The epithelial-mesenchymal transition generates cells with properties of stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Molecular definition of breast tumor heterogeneity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Stable Overexpression of Smad7 in Human Melanoma Cells Impairs Bone Metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Molecular biology of bone metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-beta type I receptor kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Inhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

An anti-transforming growth factor beta antibody suppresses metastasis via cooperative effects on multiple cell compartments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Smad-binding defective mutant of transforming growth factor beta type I receptor enhances tumorigenesis but suppresses metastasis of breast cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP- and HGF-mediated signaling networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Transforming growth factor-beta regulates mammary carcinoma cell survival and interaction with the adjacent microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Enhanced hepatocyte growth factor signaling by type II transforming growth factor-beta receptor knockout fibroblasts promotes mammary tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

The loss of TGF-beta signaling promotes prostate cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Development of TGF-beta signalling inhibitors for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Genes that mediate breast cancer metastasis to lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Myc suppression of the p21 Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.294

Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein

21 January 2018

1 reference

12 December 2020

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

1 reference

12 December 2020

Group 2 coronaviruses prevent immediate early interferon induction by protection of viral RNA from host cell recognition

1 reference

12 December 2020

Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation

1 reference

12 December 2020

Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

1 reference

12 December 2020

Treatment of SARS with human interferons

1 reference

12 December 2020

The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.

1 reference

12 December 2020

Toll-like receptor 3 mediates a more potent antiviral response than Toll-like receptor 4

1 reference

12 December 2020

Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

1 reference

12 December 2020

Involvement of the IkappaB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation

1 reference

12 December 2020

Triggering the interferon response: the role of IRF-3 transcription factor

1 reference

12 December 2020

The host type I interferon response to viral and bacterial infections

1 reference

12 December 2020

The Immunobiology of SARS*.

1 reference

12 December 2020

Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus

1 reference

12 December 2020

Persistent infection promotes cross-species transmissibility of mouse hepatitis virus

1 reference

12 December 2020

Identification of mouse hepatitis virus papain-like proteinase 2 activity

1 reference

12 December 2020

Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage

1 reference

12 December 2020

Cell type-specific involvement of RIG-I in antiviral response

1 reference

12 December 2020

Systematic assembly of a full-length infectious cDNA of mouse hepatitis virus strain A59.

1 reference

12 December 2020

Interferon regulatory factor 7 is activated by a viral oncoprotein through RIP-dependent ubiquitination.

1 reference

12 December 2020

Specific cleavage of Mcl-1 by caspase-3 in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in Jurkat leukemia T cells

1 reference

12 December 2020

Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1.

1 reference

12 December 2020

Mouse hepatitis virus does not induce Beta interferon synthesis and does not inhibit its induction by double-stranded RNA.

1 reference

12 December 2020

SARS coronavirus and innate immunity

1 reference

12 December 2020

Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK

1 reference

12 December 2020

Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection

1 reference

12 December 2020

DUBA: a deubiquitinase that regulates type I interferon production

1 reference

12 December 2020

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction

1 reference

12 December 2020

Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif

1 reference

12 December 2020

An efficient one-step site-directed and site-saturation mutagenesis protocol

1 reference

12 December 2020

Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonists

1 reference

12 December 2020

Molecular determinants of polyubiquitin linkage selection by an HECT ubiquitin ligase

1 reference

12 December 2020

The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter

1 reference

12 December 2020

The papain-like protease of severe acute respiratory syndrome coronavirus has deubiquitinating activity

1 reference

12 December 2020

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

1 reference

12 December 2020

IRF3 mediates a TLR3/TLR4-specific antiviral gene program

1 reference

12 December 2020

IRF family of transcription factors as regulators of host defense

1 reference

12 December 2020

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

1 reference

12 December 2020

Isolation of coronavirus envelope glycoproteins and interaction with the viral nucleocapsid

1 reference

12 December 2020

Ubiquitin: structures, functions, mechanisms

1 reference

12 December 2020

Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain

1 reference

12 December 2020

Potent inhibition of SARS-associated coronavirus (SCOV) infection and replication by type I interferons (IFN-alpha/beta) but not by type II interferon (IFN-gamma).

1 reference

12 December 2020

Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20.

1 reference

12 December 2020

A new infectious disease challenge: Urbani severe acute respiratory syndrome (SARS) associated coronavirus

1 reference

12 December 2020

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

1 reference

12 December 2020

Toll-like receptors and innate immunity

1 reference

12 December 2020

Expression profile of immune response genes in patients with Severe Acute Respiratory Syndrome

1 reference

12 December 2020

Identifiers

DOI

10.1038/CR.2008.294

1 reference

Dimensions Publication ID

15 September 2017

0 references

0 references

1 reference