(Q28131738)

Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry

31 March 2020

1 reference

Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series

31 March 2020

1 reference

A genomic and functional inventory of deubiquitinating enzymes

31 March 2020

1 reference

Ubiquitin-binding domains

31 March 2020

1 reference

High incidence of ubiquitin-like domains in human ubiquitin-specific proteases

31 March 2020

1 reference

Ubiquitin and ubiquitin-like specific proteases targeted by infectious pathogens: Emerging patterns and molecular principles

31 March 2020

1 reference

Structure of the A20 OTU domain and mechanistic insights into deubiquitination

31 March 2020

1 reference

Catalytic mechanism in papain family of cysteine peptidases

31 March 2020

1 reference

Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde

31 March 2020

1 reference

Recognition of polyubiquitin isoforms by the multiple ubiquitin binding modules of isopeptidase T.

31 March 2020

1 reference

Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14

31 March 2020

1 reference

Amino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8)

31 March 2020

1 reference

The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module

31 March 2020

1 reference

Structural basis and specificity of human otubain 1-mediated deubiquitination

31 March 2020

1 reference

Molecular Basis for the Unique Deubiquitinating Activity of the NF-κB Inhibitor A20

31 March 2020

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Crystal structure of human otubain 2.

31 March 2020

1 reference

Structural Basis for Ubiquitin Recognition by the Otu1 Ovarian Tumor Domain Protein

31 March 2020

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Crystal structure of a deubiquitinating enzyme (human UCH-L3) at 1.8 A resolution

31 March 2020

1 reference

Structural basis for the specificity of ubiquitin C-terminal hydrolases

31 March 2020

1 reference

Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

31 March 2020

1 reference

Substrate filtering by the active site crossover loop in UCHL3 revealed by sortagging and gain-of-function mutations

31 March 2020

1 reference

Substrate specificity of deubiquitinating enzymes: ubiquitin C-terminal hydrolases

31 March 2020

1 reference

SCA3: neurological features, pathogenesis and animal models

31 March 2020

1 reference

The solution structure of the Josephin domain of ataxin-3: structural determinants for molecular recognition

31 March 2020

1 reference

Deubiquitinating function of ataxin-3: insights from the solution structure of the Josephin domain

31 March 2020

1 reference

Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains

31 March 2020

1 reference

Structure of the Jab1/MPN Domain and Its Implications for Proteasome Function

31 March 2020

1 reference

MPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function

31 March 2020

1 reference

A cryptic protease couples deubiquitination and degradation by the proteasome

31 March 2020

1 reference

Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1.

31 March 2020

1 reference

Activation of the endosome-associated ubiquitin isopeptidase AMSH by STAM, a component of the multivesicular body-sorting machinery

31 March 2020

1 reference

Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair

31 March 2020

1 reference

Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage

31 March 2020

1 reference

The Rap80-BRCC36 de-ubiquitinating enzyme complex antagonizes RNF8-Ubc13-dependent ubiquitination events at DNA double strand breaks

31 March 2020

1 reference

K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1

31 March 2020

1 reference

Positional-scanning fluorigenic substrate libraries reveal unexpected specificity determinants of DUBs (deubiquitinating enzymes).

31 March 2020

1 reference

Screen for ISG15-crossreactive deubiquitinases

31 March 2020

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Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses

31 March 2020

1 reference

UBP43 (USP18) specifically removes ISG15 from conjugated proteins

31 March 2020

1 reference

Identification of a novel isopeptidase with dual specificity for ubiquitin- and NEDD8-conjugated proteins

31 March 2020

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Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

31 March 2020

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Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation

31 March 2020

1 reference

Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1

31 March 2020

1 reference

Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains

31 March 2020

1 reference

DUBA: a deubiquitinase that regulates type I interferon production

31 March 2020

1 reference

AMSH is an endosome-associated ubiquitin isopeptidase

31 March 2020

1 reference

Clathrin anchors deubiquitinating enzymes, AMSH and AMSH-like protein, on early endosomes

31 March 2020

1 reference

The deubiquitinating enzyme ataxin-3, a polyglutamine disease protein, edits Lys63 linkages in mixed linkage ubiquitin chains.

31 March 2020

1 reference

Control of AMPK-related kinases by USP9X and atypical Lys(29)/Lys(33)-linked polyubiquitin chains

31 March 2020

1 reference

The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin

31 March 2020

1 reference

In vivo disassembly of free polyubiquitin chains by yeast Ubp14 modulates rates of protein degradation by the proteasome

31 March 2020

1 reference

The age of crosstalk: phosphorylation, ubiquitination, and beyond

31 March 2020

1 reference

Regulation of the deubiquitinating enzyme CYLD by IkappaB kinase gamma-dependent phosphorylation

31 March 2020

1 reference

14-3-3-dependent inhibition of the deubiquitinating activity of UBPY and its cancellation in the M phase.

31 March 2020

1 reference

Final stages of cytokinesis and midbody ring formation are controlled by BRUCE

31 March 2020

1 reference

Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis

31 March 2020

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Ubiquitination directly enhances activity of the deubiquitinating enzyme ataxin-3

31 March 2020

1 reference

Mechanism and consequences for paralog-specific sumoylation of ubiquitin-specific protease 25

31 March 2020

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Differential redox regulation within the PTP superfamily

31 March 2020

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Hydrogen peroxide prolongs nuclear localization of NF-kappaB in activated cells by suppressing negative regulatory mechanisms.

31 March 2020

1 reference

T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20

31 March 2020

1 reference

The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradation

31 March 2020

1 reference

Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kappaB activation

31 March 2020

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Ubiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteins

31 March 2020

1 reference

Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex

31 March 2020

1 reference

An inhibitor of a deubiquitinating enzyme regulates ubiquitin homeostasis

31 March 2020

1 reference

Protein partners of deubiquitinating enzymes

31 March 2020

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A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway

31 March 2020

1 reference

GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7

31 March 2020

1 reference

The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation

31 March 2020

1 reference

Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics

31 March 2020

1 reference

Regulation of mitochondrial morphology by USP30, a deubiquitinating enzyme present in the mitochondrial outer membrane

31 March 2020

1 reference

Nucleolar structure and function are regulated by the deubiquitylating enzyme USP36.

31 March 2020

1 reference

K63-linked ubiquitin chains as a specific signal for protein sorting into the multivesicular body pathway

31 March 2020

1 reference

Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation

31 March 2020

1 reference

Targeting ubiquitin specific proteases for drug discovery

31 March 2020

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Deubiquitinating enzymes as novel anticancer targets

31 March 2020

1 reference

Targeting the ubiquitin system in cancer therapy

31 March 2020

1 reference

The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer

31 March 2020

1 reference

The ubiquitin-specific protease USP28 is required for MYC stability

31 March 2020

1 reference

Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities

31 March 2020

1 reference

Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain

31 March 2020

1 reference

Endocytosis: the DUB version

31 March 2020

1 reference

The deubiquitinating enzyme UCH-L3 regulates the apical membrane recycling of the epithelial sodium channel

31 March 2020

1 reference

A deubiquitinating enzyme UBPY regulates the level of protein ubiquitination on endosomes

31 March 2020

1 reference

Vasopressin-inducible ubiquitin-specific protease 10 increases ENaC cell surface expression by deubiquitylating and stabilizing sorting nexin 3

31 March 2020

1 reference

Ubiquitination of a novel deubiquitinating enzyme requires direct binding to von Hippel-Lindau tumor suppressor protein

31 March 2020

1 reference

USP19 deubiquitinating enzyme supports cell proliferation by stabilizing KPC1, a ubiquitin ligase for p27Kip1

31 March 2020

1 reference

Neuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1

31 March 2020

1 reference

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

31 March 2020

1 reference

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

31 March 2020

1 reference

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

31 March 2020

1 reference

The p53--Mdm2--HAUSP complex is involved in p53 stabilization by HAUSP.

31 March 2020

1 reference

A20 inhibits NF-kappaB activation by dual ubiquitin-editing functions

31 March 2020

1 reference

Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome

31 March 2020

1 reference

Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome

31 March 2020

1 reference

Ubiquitin chains are remodeled at the proteasome by opposing ubiquitin ligase and deubiquitinating activities.

31 March 2020

1 reference

Multiple associated proteins regulate proteasome structure and function

31 March 2020

1 reference

Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1.

31 March 2020

1 reference

A ubiquitin stress response induces altered proteasome composition.

31 March 2020

1 reference

Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation.

31 March 2020

1 reference

The Doa4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathways

31 March 2020

1 reference

Analysis of the deubiquitinating enzymes of the yeast Saccharomyces cerevisiae

31 March 2020

1 reference

Role of ubiquitin- and Ubl-binding proteins in cell signaling

31 March 2020

1 reference

A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation

31 March 2020

1 reference

Regulation of cell cycle progression and gene expression by H2A deubiquitination

31 March 2020

1 reference

Human USP3 is a chromatin modifier required for S phase progression and genome stability

31 March 2020

1 reference

The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression

31 March 2020

1 reference

The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway

31 March 2020

1 reference

Deubiquitination of FANCD2 is required for DNA crosslink repair

31 March 2020

1 reference

Ubiquitin in NF-kappaB signaling.

31 March 2020

1 reference

Deubiquitylation and regulation of the immune response

31 March 2020

1 reference

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

31 March 2020

1 reference

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

31 March 2020

1 reference

Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma.

31 March 2020

1 reference

Frequent inactivation of A20 in B-cell lymphomas

31 March 2020

1 reference

TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma

31 March 2020

1 reference

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

31 March 2020

1 reference

The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20

31 March 2020

1 reference

The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signalling

31 March 2020

1 reference

NF-kappaB suppression by the deubiquitinating enzyme Cezanne: a novel negative feedback loop in pro-inflammatory signaling

31 March 2020

1 reference

FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination

31 March 2020

1 reference

USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity

31 March 2020

1 reference

Ab initio protein modelling reveals novel human MIT domains

31 March 2020

1 reference

The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence

31 March 2020

1 reference

Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases

31 March 2020

1 reference

Structure of a multipartite protein-protein interaction domain in splicing factor prp8 and its link to retinitis pigmentosa

31 March 2020

1 reference

Structure of the ubiquitin hydrolase UCH-L3 complexed with a suicide substrate

31 March 2020

1 reference

Josephin domain of ataxin-3 contains two distinct ubiquitin-binding sites.

31 March 2020

1 reference

12 December 2020

Defining the human deubiquitinating enzyme interaction landscape

1 reference

12 December 2020

Suppression of the deubiquitinating enzyme USP5 causes the accumulation of unanchored polyubiquitin and the activation of p53

1 reference

12 December 2020

Regulation of monoubiquitinated PCNA by DUB autocleavage

1 reference

12 December 2020

UAF1 is a subunit of multiple deubiquitinating enzyme complexes

1 reference

12 December 2020

Dissection of USP catalytic domains reveals five common insertion points

1 reference

12 December 2020

Identification of ubiquitinated histones 2A and 2B in Physarum polycephalum. Disappearance of these proteins at metaphase and reappearance at anaphase.

1 reference

12 December 2020

HAUSP is required for p53 destabilization

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRM2731

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

100815

1036789873

0 references

100815

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference