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The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20
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scholarly article
1 reference
stated in
PubMed
PubMed ID
18246070
retrieved
31 January 2017
title
The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20
(English)
1 reference
stated in
PubMed
PubMed ID
18246070
retrieved
31 January 2017
main subject
inflammation
0 references
Tax1 (human T cell leukemia virus type I) binding protein 1
1 reference
stated in
GOA release 2020-03-11
Receptor (TNFRSF)-interacting serine-threonine kinase 1
1 reference
stated in
GOA release 2020-03-11
Itchy, E3 ubiquitin protein ligase
1 reference
stated in
GOA release 2020-03-11
author
Neal G. Copeland
series ordinal
4
object named as
Neal G. Copeland
1 reference
stated in
PubMed
PubMed ID
18246070
retrieved
31 January 2017
Nancy A. Jenkins
series ordinal
5
object named as
Nancy A. Jenkins
1 reference
stated in
PubMed
PubMed ID
18246070
retrieved
31 January 2017
author name string
Noula Shembade
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
18246070
retrieved
31 January 2017
Nicole S. Harhaj
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
18246070
retrieved
31 January 2017
Kislay Parvatiyar
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
18246070
retrieved
31 January 2017
Lydia E. Matesic
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
18246070
retrieved
31 January 2017
Edward W. Harhaj
series ordinal
7
1 reference
stated in
PubMed
PubMed ID
18246070
retrieved
31 January 2017
language of work or name
English
0 references
publication date
1 March 2008
1 reference
stated in
PubMed
PubMed ID
18246070
retrieved
31 January 2017
published in
Nature Immunology
1 reference
stated in
PubMed
PubMed ID
18246070
retrieved
31 January 2017
volume
9
1 reference
stated in
PubMed
PubMed ID
18246070
retrieved
31 January 2017
issue
3
1 reference
stated in
PubMed
PubMed ID
18246070
retrieved
31 January 2017
page(s)
254–262
1 reference
stated in
PubMed
PubMed ID
18246070
retrieved
31 January 2017
cites work
Resolution phase of inflammation: novel endogenous anti-inflammatory and proresolving lipid mediators and pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappaB: linking inflammation and immunity to cancer development and progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic inflammation: a failure of resolution?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling to NF-kappaB
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Negative regulation of JNK signaling by the tumor suppressor CYLD.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappaB is essential for induction of CYLD, the negative regulator of NF-kappaB: evidence for a novel inducible autoregulatory feedback pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IkappaB kinase beta phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-kappaB pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential role for TAX1BP1 in the termination of TNF-alpha-, IL-1- and LPS-mediated NF-kappaB and JNK signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T6BP, a TRAF6-interacting protein involved in IL-1 signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T6BP and NDP52 are myosin VI binding partners with potential roles in cytokine signalling and cell adhesion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A human suppressor of c-Jun N-terminal kinase 1 activation by tumor necrosis factor alpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human T cell leukemia virus type I and neurologic disease: events in bone marrow, peripheral blood, and central nervous system during normal immune surveillance and neuroinflammation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of persistent NF-kappaB activation by HTLV-I tax.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human T-cell leukemia virus oncoprotein tax represses nuclear receptor-dependent transcription by targeting coactivator TAX1BP1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of a novel protein-binding module--the WW domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lethal cutaneous disease in transgenic mice conditionally expressing type I human T cell leukemia virus Tax.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ABIN-1 binds to NEMO/IKKgamma and co-operates with A20 in inhibiting NF-kappaB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
LIND/ABIN-3 is a novel lipopolysaccharide-inducible inhibitor of NF-kappaB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRAF1 is a negative regulator of TNF signaling. enhanced TNF signaling in TRAF1-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Retroviral oncoprotein Tax deregulates NF-kappaB by activating Tak1 and mediating the physical association of Tak1-IKK
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human T cell leukemia virus type I (HTLV-I) and human diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional dichotomy of A20 in apoptotic and necrotic cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of NF-kappa B by the human T cell leukemia virus type I Tax oncoprotein is associated with ubiquitin-dependent relocalization of I kappa B kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human T-cell leukemia virus type 1 Tax oncoprotein requires the ubiquitin-conjugating enzyme Ubc13 for NF-kappaB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI1563
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/NI1563
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4146237
OpenCitations bibliographic resource ID
4146237
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4146237
PubMed ID
18246070
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4146237
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