Wikidata

(Q21981433)

English

Receptor (TNFRSF)-interacting serine-threonine kinase 1

mammalian protein found in Mus musculus

  • receptor-interacting protein 1
  • RIP-1
  • cell death protein RIP
  • receptor-interacting serine/threonine-protein kinase 1
  • Ripk1
  • serine/threonine-protein kinase RIP
In more languages
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No label defined

No description defined

Statements

molecular function
protein binding
determination method or standard
IPI
17 references
retrieved
7 November 2018
stated in
PELI1 Selectively Targets Kinase-Active RIP3 for Ubiquitylation-Dependent Proteasomal Degradation.
GOA
curator
UniProt
UniProt protein ID
Q60855
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IPI
retrieved
7 November 2018
stated in
Pellino3 targets RIP1 and regulates the pro-apoptotic effects of TNF-α
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IPI
retrieved
7 November 2018
stated in
Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IPI
retrieved
7 November 2018
stated in
Optineurin negatively regulates TNFalpha- induced NF-kappaB activation by competing with NEMO for ubiquitinated RIP
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IPI
retrieved
7 November 2018
stated in
FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IPI
retrieved
7 November 2018
stated in
NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IPI
retrieved
7 November 2018
stated in
Beyond tumor necrosis factor receptor: TRADD signaling in toll-like receptors.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IPI
retrieved
7 November 2018
stated in
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IPI
retrieved
7 November 2018
stated in
Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IPI
retrieved
7 November 2018
stated in
cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IPI
retrieved
7 November 2018
stated in
Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IPI
retrieved
7 November 2018
stated in
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IPI
retrieved
7 November 2018
stated in
Tumour necrosis factor receptor 1 mediates endoplasmic reticulum stress-induced activation of the MAP kinase JNK
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IPI
retrieved
7 November 2018
stated in
The mitochondrial serine protease HtrA2/Omi cleaves RIP1 during apoptosis of Ba/F3 cells induced by growth factor withdrawal
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IPI
retrieved
7 November 2018
stated in
Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IPI
retrieved
7 November 2018
stated in
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IPI
retrieved
7 November 2018
stated in
The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IPI
protein serine/threonine kinase activity
determination method or standard
IBA
IDA
IEA
ISO
ISS
6 references
retrieved
7 November 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q60855
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
ISS
retrieved
7 November 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
ISO
retrieved
7 November 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q60855
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IEA
retrieved
7 November 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IEA
retrieved
7 November 2018
stated in
SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination.
GOA
curator
UniProt
UniProt protein ID
Q60855
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IDA
retrieved
7 November 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IBA
cell component
biological process
necroptosis
determination method or standard
IDA
IEA
IGI
ISO
6 references
retrieved
7 November 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
ISO
retrieved
7 November 2018
stated in
Caspase 8 inhibits programmed necrosis by processing CYLD
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IGI
retrieved
7 November 2018
stated in
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IGI
retrieved
7 November 2018
stated in
cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IGI
retrieved
7 November 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IEA
retrieved
7 November 2018
stated in
SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination.
GOA
curator
UniProt
UniProt protein ID
Q60855
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60855&geneProductId=UniProtKB:Q60855
determination method or standard
IDA

Identifiers

 
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                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21981433&oldid=2023206622"