(Q28593092)

31 January 2017

title

NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis (English)

1 reference

Fas (TNFRSF6)-associated via death domain

31 January 2017

0 references

0 references

1 reference

GOA release 2020-03-11

1 reference

Receptor (TNFRSF)-interacting serine-threonine kinase 1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

hepatocellular carcinoma

1 reference

Vangelis Kondylis

1

0 references

Beate K Straub

object named as

Beate Katharina Straub

5

0 references

Laura Ochoa-callejero

object named as

Laura Ochoa-Callejero

4

0 references

Manolis Pasparakis

object named as

Manolis Pasparakis

14

0 references

author name string

Apostolos Polykratis

2

1 reference

31 January 2017

Hanno Ehlken

3

1 reference

31 January 2017

Santosh Krishna-Subramanian

6

1 reference

31 January 2017

Trieu-My Van

7

1 reference

31 January 2017

Harald-Morten Curth

8

1 reference

31 January 2017

Nicole Heise

9

1 reference

31 January 2017

Falk Weih

10

1 reference

31 January 2017

Ulf Klein

11

1 reference

31 January 2017

Peter Schirmacher

12

1 reference

31 January 2017

Michelle Kelliher

13

1 reference

31 January 2017

publication date

9 November 2015

1 reference

31 January 2017

1 reference

31 January 2017

volume

28

1 reference

31 January 2017

issue

5

1 reference

31 January 2017

page(s)

582–598

1 reference

describes a project that uses

31 January 2017

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4644221/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members

17 March 2017

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17 March 2017

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TNF-alpha induces two distinct caspase-8 activation pathways

17 March 2017

1 reference

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Competitive control of independent programs of tumor necrosis factor receptor-induced cell death by TRADD and RIP1

17 March 2017

1 reference

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Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

17 March 2017

1 reference

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Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

17 March 2017

1 reference

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17 March 2017

Hepatocellular carcinoma

1 reference

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NF-kappaB functions as a tumour promoter in inflammation-associated cancer

7 April 2017

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7 April 2017

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7 April 2017

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Germinal center B cell maintenance and differentiation are controlled by distinct NF-κB transcription factor subunits

29 September 2017

1 reference

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RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis

29 September 2017

1 reference

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29 September 2017

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Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo

29 September 2017

1 reference

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Death receptor-independent FADD signalling triggers hepatitis and hepatocellular carcinoma in mice with liver parenchymal cell-specific NEMO knockout.

29 September 2017

1 reference

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29 September 2017

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29 September 2017

1 reference

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Control of life-or-death decisions by RIP1 kinase

29 September 2017

1 reference

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NEMO inhibits programmed necrosis in an NFκB-independent manner by restraining RIP1.

29 September 2017

1 reference

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The noncanonical NF-κB pathway

29 September 2017

1 reference

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29 September 2017

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29 September 2017

1 reference

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29 September 2017

1 reference

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NF-κB in the liver--linking injury, fibrosis and hepatocellular carcinoma

29 September 2017

1 reference

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Cell death and hepatocarcinogenesis: Dysregulation of apoptosis signaling pathways.

29 September 2017

1 reference

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Regulation of tissue homeostasis by NF-kappaB signalling: implications for inflammatory diseases

29 September 2017

1 reference

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A lymphotoxin-driven pathway to hepatocellular carcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4644221

Hepatocellular carcinoma: current trends in worldwide epidemiology, risk factors, diagnosis and therapeutics.

29 September 2017

1 reference

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NEMO/IKKgamma regulates an early NF-kappaB-independent cell-death checkpoint during TNF signaling

29 September 2017

1 reference

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NF-kappaB signaling, liver disease and hepatoprotective agents

29 September 2017

1 reference

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IKK1 and IKK2 cooperate to maintain bile duct integrity in the liver

29 September 2017

1 reference

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Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4644221

TNFR1 determines progression of chronic liver injury in the IKKγ/Nemo genetic model

29 September 2017

1 reference

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Genetic inactivation of RelA/p65 sensitizes adult mouse hepatocytes to TNF-induced apoptosis in vivo and in vitro.

3 June 2018

1 reference

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Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces non-apoptotic liver injury.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4644221

RelA and RelB transcription factors in distinct thymocyte populations control lymphotoxin-dependent interleukin-17 production in γδ T cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4644221

Canonical NF-κB Activity, Dispensable for B Cell Development, Replaces BAFF-Receptor Signals and Promotes B Cell Proliferation upon Activation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4644221

IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4644221

NEMO/IKK gamma-deficient mice model incontinentia pigmenti.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4644221

Hepatocyte-specific expression of Cre recombinase

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4644221

NEMO expression in human hepatocellular carcinoma and its association with clinical outcome

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/26555174

12 December 2020

inferred from PubMed ID database lookup

Deletion of NEMO/IKKγ in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular Carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/26555174

12 December 2020

inferred from PubMed ID database lookup

Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/26555174

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.CCELL.2015.10.001

1 reference

1 reference

1 reference

1 reference