(Q33797174)

29 July 2017

1 reference

title

Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases (English)

1 reference

Human T-lymphotropic virus 1

29 July 2017

main subject

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NF-κB

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author name string

S C Sun

series ordinal

1

1 reference

29 July 2017

D W Ballard

series ordinal

2

1 reference

29 July 2017

language of work or name

English

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publication date

1 November 1999

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29 July 2017

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29 July 2017

volume

18

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29 July 2017

issue

49

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29 July 2017

page(s)

6948-6958

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Characterization of peripheral blood T-lymphocytes transduced with HTLV-I Tax mutants with different trans-activating phenotypes

29 July 2017

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c-fos promoter trans-activation by the tax1 protein of human T-cell leukemia virus type I

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Interaction of HTLV-1 Tax1 with p67SRF causes the aberrant induction of cellular immediate early genes through CArG boxes

21 January 2018

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High rate of chromosomal abnormalities in HTLV-I-infected T-cell colonies derived from prodromal phase of adult T-cell leukemia: a study of IL-2-stimulated colony formation in methylcellulose

21 January 2018

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Cytogenetic studies on the adult T-cell leukemia in Japan.

21 January 2018

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Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases

21 January 2018

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Multiple mutations contribute to the oncogenicity of the retroviral oncoprotein v-Rel

21 January 2018

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Constitutive dephosphorylation and activation of a member of the nuclear factor of activated T cells, NF-AT1, in Tax-expressing and type I human T-cell leukemia virus-infected human T cells

21 January 2018

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Transformation to continuous growth of primary human T lymphocytes by human T-cell leukemia virus type I X-region genes transduced by a Herpesvirus saimiri vector

21 January 2018

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HIV-1, HTLV-1 and normal T-cell growth: transcriptional strategies and surprises

21 January 2018

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21 January 2018

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21 January 2018

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IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein

21 January 2018

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Induction of OX40, a receptor of gp34, on T cells by trans-acting transcriptional activator, Tax, of human T-cell leukemia virus type I.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

21 January 2018

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JNK or IKK, AP-1 or NF-kappaB, which are the targets for MEK kinase 1 action?

21 January 2018

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Ablation of transplanted HTLV-I Tax-transformed tumors in mice by antisense inhibition of NF-kappa B

21 January 2018

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Control of cAMP-regulated enhancers by the viral transactivator Tax through CREB and the co-activator CBP.

21 January 2018

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Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

21 January 2018

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MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

21 January 2018

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HTLV-1 transactivator induces interleukin-2 receptor expression through an NF-kappa B-like factor.

21 January 2018

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Recombinant IkappaB kinases alpha and beta are direct kinases of Ikappa Balpha

21 January 2018

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Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

21 January 2018

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Identification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis

21 January 2018

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The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

21 January 2018

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Cotranslational biogenesis of NF-kappaB p50 by the 26S proteasome

21 January 2018

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The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-kappaB acting through the NF-kappaB-inducing kinase and IkappaB kinases

21 January 2018

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NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

21 January 2018

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Phosphorylation of p105 PEST sequence via a redox-insensitive pathway up-regulates processing of p50 NF-kappaB.

21 January 2018

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21 January 2018

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Signal transduction through NF-kappa B.

21 January 2018

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21 January 2018

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p105 and p98 precursor proteins play an active role in NF-kappa B-mediated signal transduction

21 January 2018

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IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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HTLV-1 Tax enhances NF-kappa B2 expression and binds to the products p52 and p100, but does not suppress the inhibitory function of p100.

21 January 2018

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Transcriptional activation of the interleukin-6 gene by HTLV-1 p40tax through an NF-kappa B-like binding site

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Molecular mechanisms of promoter regulation of the gp34 gene that is trans-activated by an oncoprotein Tax of human T cell leukemia virus type I.

21 January 2018

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Structural motifs involved in ubiquitin-mediated processing of the NF-kappaB precursor p105: roles of the glycine-rich region and a downstream ubiquitination domain

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

21 January 2018

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The human T-lymphotropic virus type I tax gene can cooperate with the ras oncogene to induce neoplastic transformation of cells

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Expression of the pX gene of HTLV-I: general splicing mechanism in the HTLV family

21 January 2018

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Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I.

21 January 2018

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Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes

21 January 2018

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A transcriptional activator protein encoded by the x-lor region of the human T-cell leukemia virus

21 January 2018

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Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel gene

21 January 2018

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NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

21 January 2018

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Autoregulation of the NF-kappa B transactivator RelA (p65) by multiple cytoplasmic inhibitors containing ankyrin motifs

21 January 2018

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The trans-activator tax of human T-cell leukemia virus type 1 (HTLV-1) interacts with cAMP-responsive element (CRE) binding and CRE modulator proteins that bind to the 21-base-pair enhancer of HTLV-1.

21 January 2018

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Oncogenic transformation by the tax gene of human T-cell leukemia virus type I in vitro

21 January 2018

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Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

21 January 2018

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c-sis/PDGF-B promoter transactivation by the Yax protein of human T-cell leukemia virus type 1.

21 January 2018

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NF-kappaB-inducing kinase and IkappaB kinase participate in human T-cell leukemia virus I Tax-mediated NF-kappaB activation

21 January 2018

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Transcriptional repression of p53 by human T-cell leukemia virus type I Tax protein

21 January 2018

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HTLV x-gene product: requirement for the env methionine initiation codon.

21 January 2018

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HTLV-I Tax protein stimulation of DNA binding of bZIP proteins by enhancing dimerization

21 January 2018

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Stable expression of the tax gene of type I human T-cell leukemia virus in human T cells activates specific cellular genes involved in growth

21 January 2018

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I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity

21 January 2018

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IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

21 January 2018

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Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203220

HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation

21 January 2018

1 reference

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Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease

21 January 2018

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Direct Phosphorylation of IB by IKK and IKK: Discrimination Between Free and NF-B-Bound Substrate

21 January 2018

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Interaction of the human T-cell lymphotrophic virus type I (HTLV-I) transcriptional activator Tax with cellular factors that bind specifically to the 21-base-pair repeats in the HTLV-I enhancer

21 January 2018

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Human T-cell lymphotropic virus type I (HTLV-I) transcriptional activator, Tax, enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interaction

21 January 2018

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Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta

21 January 2018

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Human T-cell leukemia virus type I Tax induces expression of the Rel-related family of kappa B enhancer-binding proteins: evidence for a pretranslational component of regulation

21 January 2018

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7 January 2021

Interaction of HTLV-I Tax with the human proteasome: implications for NF-kappa B induction

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7 January 2021

IKAP is a scaffold protein of the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203220

7 January 2021

Induction of tumor necrosis factor alpha in human neuronal cells by extracellular human T-cell lymphotropic virus type 1 Tax.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203220

7 January 2021

Persistent activation of NF-kappa B/Rel by human T-cell leukemia virus type 1 tax involves degradation of I kappa B beta.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203220

7 January 2021

NF-kappa B and Rel: participants in a multiform transcriptional regulatory system.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203220

7 January 2021

Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203220

7 January 2021

Extracellular Tax1 protein stimulates tumor necrosis factor-beta and immunoglobulin kappa light chain expression in lymphoid cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203220

7 January 2021

Strong trans activation of the human cytomegalovirus major immediate-early enhancer by p40tax of human T-cell leukemia virus type I via two repetitive tax-responsive sequence elements

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203220

7 January 2021

Activation of endogenous c-fos proto-oncogene expression by human T-cell leukemia virus type I-encoded p40tax protein in the human T-cell line, Jurkat

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203220

7 January 2021

Immortalization of CD4(+) and CD8(+) T lymphocytes by human T-cell leukemia virus type 1 Tax mutants expressed in a functional molecular clone

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203220

7 January 2021

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203220

7 January 2021

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203220

7 January 2021

Mutational analysis of human T-cell leukemia virus type I Tax: regions necessary for function determined with 47 mutant proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203220

7 January 2021

Chromosome abnormalities, sister chromatid exchanges, and cell cycle analysis in phytohemagglutinin-stimulated adult T cell leukemia lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203220

7 January 2021

Differential transactivation of the intercellular adhesion molecule 1 gene promoter by Tax1 and Tax2 of human T-cell leukemia viruses.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203220

7 January 2021

NF-kappa B: a lesson in family values

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203220

7 January 2021

I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203220

7 January 2021

Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203220

7 January 2021

A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203220

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203220

1 reference

Dimensions Publication ID

29 July 2017

1022270894

0 references

1 reference