(Q36836192)

English

The effect of difluoromethylornithine on decreasing prostate size and polyamines in men: results of a year-long phase IIb randomized placebo-controlled chemoprevention trial

scientific article published on February 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

The effect of difluoromethylornithine on decreasing prostate size and polyamines in men: results of a year-long phase IIb randomized placebo-controlled chemoprevention trial (English)

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

0 references

Hoda Anton-Culver

10

object named as

Hoda Anton-Culver

0 references

Argyrios Ziogas

4

object named as

Argyrios Ziogas

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Thomas E Ahlering

0 references

Frank L. Meyskens, Jr.

11

object named as

Frank L Meyskens

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

author name string

Anne R Simoneau

1

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Eugene W Gerner

2

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Ray Nagle

3

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Sharon Fujikawa-Brooks

5

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Hagit Yerushalmi

6

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Thomas E Ahlering

7

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Ronald Lieberman

8

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Christine E McLaren

9

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

publication date

1 February 2008

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Cancer Epidemiology, Biomarkers & Prevention

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

17

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

292-299

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

29 September 2017

Rationale for, and design of, a clinical trial targeting polyamine metabolism for colon cancer chemoprevention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

29 September 2017

Ornithine decarboxylase polymorphism modification of response to aspirin treatment for colorectal adenoma prevention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

29 September 2017

A comprehensive strategy to combat colon cancer targeting the adenomatous polyposis coli tumor suppressor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

29 September 2017

Polyamines and cancer: old molecules, new understanding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

29 September 2017

Polyamines as clinical laboratory tools

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

29 September 2017

Pathological and molecular mechanisms of prostate carcinogenesis: implications for diagnosis, detection, prevention, and treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

29 September 2017

The influence of finasteride on the development of prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

29 September 2017

Pronounced reduction in adenoma recurrence associated with aspirin use and a polymorphism in the ornithine decarboxylase gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

29 September 2017

Phase III randomized study of postradiotherapy chemotherapy with combination alpha-difluoromethylornithine-PCV versus PCV for anaplastic gliomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

29 September 2017

The ageing male: demographics and challenges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

29 September 2017

Phase III trial of accelerated hyperfractionation with or without difluromethylornithine (DFMO) versus standard fractionated radiotherapy with or without DFMO for newly diagnosed patients with glioblastoma multiforme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

29 September 2017

Toxicity evaluation of difluoromethylornithine: doses for chemoprevention trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

29 September 2017

Serum prostate-specific antigen in a community-based population of healthy men. Establishment of age-specific reference ranges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

29 September 2017

Polyamines in normal and cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

29 September 2017

Inhibition of tumor promotion by DL-alpha-difluoromethylornithine, a specific irreversible inhibitor of ornithine decarboxylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

29 September 2017

Altered polyamine profiles in prostatic hyperplasia and in kidney tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

29 September 2017

A phase II breast cancer chemoprevention trial of oral alpha-difluoromethylornithine: breast tissue, imaging, and serum and urine biomarkers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

27 June 2018

Polyamines in the male reproductive system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

27 June 2018

Gastrointestinal tissue polyamine contents of patients with Barrett's esophagus treated with alpha-difluoromethylornithine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

27 June 2018

The growth of MAT-LyLu rat prostatic adenocarcinoma can be prevented in vivo by polyamine deprivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

27 June 2018

Polyamine contents in rectal and buccal mucosae in humans treated with oral difluoromethylornithine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

27 June 2018

Effects of α-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on testosterone-induced regeneration of prostate and seminal vesicle in castrated rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

27 June 2018

Effect of α-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on polyamine levels in rat tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

27 June 2018

Results of a phase II double-blinded randomized clinical trial of difluoromethylornithine for cervical intraepithelial neoplasia grades 2 to 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

5 September 2018

Differences in ornithine decarboxylase and androgen receptor allele frequencies among ethnic groups

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

5 September 2018

Chemoprevention of prostate cancer in men at high risk: rationale and design of the reduction by dutasteride of prostate cancer events (REDUCE) trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

5 September 2018

Activated polyamine catabolism depletes acetyl-CoA pools and suppresses prostate tumor growth in TRAMP mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

5 September 2018

Annual report to the nation on the status of cancer, 1975-2001, with a special feature regarding survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

5 September 2018

Association among an ornithine decarboxylase polymorphism, androgen receptor gene (CAG) repeat length and prostate cancer risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

5 September 2018

Chemoprevention of prostate carcinogenesis by DFMO and/or finasteride treatment in male Wistar rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

5 September 2018

Modulation of biologic endpoints by topical difluoromethylornithine (DFMO), in subjects at high-risk for nonmelanoma skin cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

5 September 2018

SELECT: the next prostate cancer prevention trial. Selenum and Vitamin E Cancer Prevention Trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

5 September 2018

Effects of difluoromethylornithine chemoprevention on audiometry thresholds and otoacoustic emissions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

5 September 2018

Alpha-difluoromethylornithine and polyamine levels in the human prostate: results of a phase IIa trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

5 September 2018

Phase III randomized study of postradiotherapy chemotherapy with alpha-difluoromethylornithine-procarbazine, N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosurea, vincristine (DFMO-PCV) versus PCV for glioblastoma multiforme.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

5 September 2018

A randomized, placebo-controlled trial of low-dose alpha-difluoromethylornithine in individuals at risk for colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

5 September 2018

Effect of alpha-difluoromethylornithine on rectal mucosal levels of polyamines in a randomized, double-blinded trial for colon cancer prevention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

5 September 2018

Cell transformation, invasion, and angiogenesis: a regulatory role for ornithine decarboxylase and polyamines?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

5 September 2018

Ornithine decarboxylase and polyamines in colorectal neoplasia and mucosa.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

5 September 2018

Dose de-escalation chemoprevention trial of alpha-difluoromethylornithine in patients with colon polyps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515594

5 September 2018

Predictors of mortality after androgen-deprivation therapy in patients with rapidly rising prostate-specific antigen levels after local therapy for prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18268112

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemoprevention of prostate carcinogenesis by alpha-difluoromethylornithine in TRAMP mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18268112

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemoprevention of human actinic keratoses by topical 2-(difluoromethyl)-dl-ornithine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18268112

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-performance liquid chromatographic procedure for the simultaneous determination of the natural polyamines and their monoacetyl derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/18268112

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Copenhagen rat prostatic tumor ornithine decarboxylase activity (ODC) and the effect of the ODC inhibitor alpha-difluoromethylornithine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18268112

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The development of human benign prostatic hyperplasia with age

1 reference

https://pubmed.ncbi.nlm.nih.gov/18268112

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Androgen regulation of ornithine decarboxylase in human prostatic cells identified using differential display

1 reference

https://pubmed.ncbi.nlm.nih.gov/18268112

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predictors of prostate cancer-specific mortality after radical prostatectomy or radiation therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18268112

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pretreatment predictors of posttreatment PSA doubling times for patients undergoing three-dimensional conformal radiotherapy for clinically localized prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18268112

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1055-9965.EPI-07-0658

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

ResearchGate publication ID

0 references

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