(Q36837342)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125256%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

title

The design, synthesis, and evaluation of organ-specific iron chelators (English)

1 reference

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22 December 2019

4

1 reference

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22 December 2019

author name string

Raymond J Bergeron

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125256%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

Jan Wiegand

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125256%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

James S McManis

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125256%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

language of work or name

English

0 references

publication date

1 November 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125256%20AND%20SRC:MED&resulttype=core&format=json

Journal of Medicinal Chemistry

22 December 2019

published in

1 reference

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22 December 2019

volume

49

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125256%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

issue

24

1 reference

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22 December 2019

page(s)

7032-7043

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125256%20AND%20SRC:MED&resulttype=core&format=json

(S)-4,5-dihydro-2-(2-hydroxy-4-hydroxyphenyl)-4-methyl-4-thiazolecarboxylic acid polyethers: a solution to nephrotoxicity

22 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

The evolution of iron chelators for the treatment of iron overload disease and cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

Iron chelators and iron toxicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

Results of long term iron chelation treatment with deferoxamine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

Mechanism of iron toxicity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

The roles of iron in health and disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

Current issues with blood transfusions in sickle cell disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

Iron absorption and transport

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to oxidize alpha-amino acids to a family of reactive aldehydes. Mechanistic studies identifying labile intermediates along the reaction pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

Iron-chelating therapy and the treatment of thalassemia.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

Efficacy of deferoxamine in preventing complications of iron overload in patients with thalassemia major

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

Iron-catalyzed hydroxyl radical formation. Stringent requirement for free iron coordination site

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

Oxygen radicals in ulcerative colitis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

Iron chelation promoted by desazadesferrithiocin analogs: An enantioselective barrier

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

Hepatic iron concentration and total body iron stores in thalassemia major.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

Long-term treatment of transfusional iron overload with the oral iron chelator deferiprone (L1): a Dutch multicenter trial.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

Partition-variant desferrithiocin analogues: organ targeting and increased iron clearance

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

Nontransferrin-bound iron uptake by hepatocytes is increased in the Hfe knockout mouse model of hereditary hemochromatosis

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

Methoxylation of desazadesferrithiocin analogues: enhanced iron clearing efficiency

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

Insulin sensitivity and beta-cell secretion in thalassaemia major with secondary haemochromatosis: assessment by oral glucose tolerance test

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

Desferrithiocin analogue based hexacoordinate iron(III) chelators

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

Microbial iron transport: iron acquisition by pathogenic microorganisms

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2516204

Long-term outcome of continuous 24-hour deferoxamine infusion via indwelling intravenous catheters in high-risk beta-thalassemia

5 September 2018

1 reference

12 December 2020

Iron-induced liver injury

1 reference

12 December 2020

Natural history of C282Y homozygotes for hemochromatosis

1 reference

12 December 2020

The Metabolism of Iron-Dextran Given as a Total-Dose Infusion to Iron Deficient Jamaican Subjects

1 reference

12 December 2020

Survival and causes of death in thalassaemia major

1 reference

12 December 2020

A comparative evaluation of iron clearance models

1 reference

12 December 2020

Evaluation of desferrithiocin and its synthetic analogues as orally effective iron chelators

1 reference

12 December 2020

A comparison of the iron-clearing properties of 1,2-dimethyl-3-hydroxypyrid-4-one, 1,2-diethyl-3-hydroxypyrid-4-one, and deferoxamine

1 reference

12 December 2020

A comparative study of the iron-clearing properties of desferrithiocin analogues with desferrioxamine B in a Cebus monkey model

1 reference

12 December 2020

Free radicals and antioxidants: a personal view

1 reference

12 December 2020

Synthesis and biological evaluation of naphthyldesferrithiocin iron chelators

1 reference

12 December 2020

HBED: A potential alternative to deferoxamine for iron-chelating therapy

1 reference

12 December 2020

The origin of the differences in (R)- and (S)-desmethyldesferrithiocin. Iron-clearing properties

1 reference

12 December 2020

Desazadesmethyldesferrithiocin analogues as orally effective iron chelators

1 reference

12 December 2020

Effects of C-4 stereochemistry and C-4' hydroxylation on the iron clearing efficiency and toxicity of desferrithiocin analogues

1 reference

12 December 2020

Identifiers

DOI

10.1021/JM0608816

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125256%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125256%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

PubMed publication ID

17125256

1 reference