(Q36837509)

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Cellular and animal models for high-throughput screening of therapeutic agents for the treatment of the diseases of the elderly in general and Alzheimer's disease in particular(†).

scientific article published on 13 May 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Cellular and animal models for high-throughput screening of therapeutic agents for the treatment of the diseases of the elderly in general and Alzheimer's disease in particular(†). (English)

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Alzheimer's disease

0 references

author name string

Jordan L Holtzman

1

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

publication date

13 May 2013

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Frontiers in Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

4

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

59

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Long-term use of standardised Ginkgo biloba extract for the prevention of Alzheimer's disease (GuidAge): a randomised placebo-controlled trial

1 reference

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Effect of immunotherapy with bapineuzumab on cerebrospinal fluid biomarker levels in patients with mild to moderate Alzheimer disease

1 reference

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Solanezumab for the treatment of mild-to-moderate Alzheimer's disease

1 reference

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The Alzheimer's β-secretase enzyme BACE1 is required for accurate axon guidance of olfactory sensory neurons and normal glomerulus formation in the olfactory bulb

1 reference

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ER tubules mark sites of mitochondrial division

1 reference

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Mitochondria: the next (neurode)generation

1 reference

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A membrane is born: origin of the autophagosomal compartment

1 reference

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Docosahexaenoic acid supplementation and cognitive decline in Alzheimer disease: a randomized trial

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Mitochondrial autophagy in neural function, neurodegenerative disease, neuron cell death, and aging

1 reference

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BACE1 deficiency causes altered neuronal activity and neurodegeneration

1 reference

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The secretases: enzymes with therapeutic potential in Alzheimer disease

1 reference

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Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: a randomized controlled trial

1 reference

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APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

1 reference

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MAM: more than just a housekeeper

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Mitofusin 2 builds a bridge between ER and mitochondria

1 reference

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29 September 2017

Ginkgo biloba for prevention of dementia: a randomized controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3651961

29 September 2017

Growth hormone secretagogue MK-677: no clinical effect on AD progression in a randomized trial

1 reference

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Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

1 reference

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Chronic administration of R-flurbiprofen attenuates learning impairments in transgenic amyloid precursor protein mice

1 reference

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The effect of aging on the chaperone concentrations in the hepatic, endoplasmic reticulum of male rats: the possible role of protein misfolding due to the loss of chaperones in the decline in physiological function seen with age

1 reference

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BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3651961

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An evolving view of the eukaryotic oligosaccharyltransferase

1 reference

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In cerebrospinal fluid ER chaperones ERp57 and calreticulin bind beta-amyloid

1 reference

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The 1,25D3-MARRS protein: contribution to steroid stimulated calcium uptake in chicks and rats

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Biological roles of APP in the epidermis

1 reference

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Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3651961

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Ribozyme knockdown functionally links a 1,25(OH)2D3 membrane binding protein (1,25D3-MARRS) and phosphate uptake in intestinal cells.

1 reference

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Transmembrane movement of dolichol linked carbohydrates during N-glycoprotein biosynthesis in the endoplasmic reticulum

1 reference

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A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3651961

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Oligosaccharyltransferase: a complex multisubunit enzyme of the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3651961

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Age-related cognitive deficits, impaired long-term potentiation and reduction in synaptic marker density in mice lacking the beta-amyloid precursor protein

1 reference

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Molecular cloning and complete amino-acid sequence of form-I phosphoinositide-specific phospholipase C

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Prevention of age-related spatial memory deficits in a transgenic mouse model of Alzheimer's disease by chronic Ginkgo biloba treatment

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Age-dependent accumulation of dolichol in rat liver: is tissue dolichol a biomarker of aging?

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N-linked protein glycosylation in the rat parotid gland during aging

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Solubilization of rat liver vasopressin receptors as a complex with a guanine-nucleotide-binding protein and phosphoinositide-specific phospholipase C.

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Purification and characterization of a new isozyme of thiol:protein-disulfide oxidoreductase from rat hepatic microsomes. Relationship of this isozyme to cytosolic phosphatidylinositol-specific phospholipase C form 1A.

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What the halted phase III γ-secretase inhibitor trial may (or may not) be telling us.

1 reference

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Progesterone and estrogen regulate Alzheimer-like neuropathology in female 3xTg-AD mice.

1 reference

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1 reference

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17Alpha-estradiol and 17beta-estradiol treatments are effective in lowering cerebral amyloid-beta levels in AbetaPPSWE transgenic mice

1 reference

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Serum insulin-like growth factor I regulates brain amyloid-beta levels

1 reference

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A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

1 reference

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Effect of methoxychlor administration to male rats on hepatic, microsomal iodothyronine 5'-deiodinase, form I.

1 reference

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Developmental regulation and tissue-specific expression of hamster dolichol-P-dependent N-acetylglucosamine-1-P transferase (GPT).

1 reference

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Effects of treatment on morbidity in hypertension. Results in patients with diastolic blood pressures averaging 115 through 129 mm Hg

1 reference

https://pubmed.ncbi.nlm.nih.gov/23717280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of treatment on morbidity in hypertension. II. Results in patients with diastolic blood pressure averaging 90 through 114 mm Hg

1 reference

https://pubmed.ncbi.nlm.nih.gov/23717280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-β protein precursor gene expression in alzheimer's disease and other conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/23717280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The reported cDNA sequence for phospholipase C alpha encodes protein disulfide isomerase, isozyme Q-2 and not phospholipase-C

1 reference

https://pubmed.ncbi.nlm.nih.gov/23717280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FPHAR.2013.00059

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

ResearchGate publication ID

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