(Q36838785)

English

Ubiquitin ligase Smurf1 mediates tumor necrosis factor-induced systemic bone loss by promoting proteasomal degradation of bone morphogenetic signaling proteins

scientific article published on 19 June 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Ubiquitin ligase Smurf1 mediates tumor necrosis factor-induced systemic bone loss by promoting proteasomal degradation of bone morphogenetic signaling proteins (English)

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

1 reference

based on heuristic

inferred from title

author name string

Ruolin Guo

1

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Motozo Yamashita

2

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Qian Zhang

3

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Quan Zhou

4

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Di Chen

5

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

David G Reynolds

6

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Hani A Awad

7

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Laura Yanoso

8

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Lan Zhao

9

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Edward M Schwarz

10

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Ying E Zhang

11

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Brendan F Boyce

12

1 reference

Europe PubMed Central

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16 August 2017

Lianping Xing

13

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

language of work or name

0 references

publication date

19 June 2008

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

283

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

34

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

23084-23092

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

TNF-alpha inhibits BMP-induced osteoblast differentiation through activating SAPK/JNK signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Endogenous TNFalpha lowers maximum peak bone mass and inhibits osteoblastic Smad activation through NF-kappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

LIM mineralization protein-1 potentiates bone morphogenetic protein responsiveness via a novel interaction with Smurf1 resulting in decreased ubiquitination of Smads

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Activation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational change

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Negative regulation of the E3 ubiquitin ligase itch via Fyn-mediated tyrosine phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Smad6 interacts with Runx2 and mediates Smad ubiquitin regulatory factor 1-induced Runx2 degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Regulating the regulators: control of protein ubiquitination and ubiquitin-like modifications by extracellular stimuli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

The p55 TNF receptor mediates TNF inhibition of osteoblast differentiation independently of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Bone morphogenetic proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

MEKK1 regulates the AP-1 dimer repertoire via control of JunB transcription and Fra-2 protein stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Regulation of the TGFbeta signalling pathway by ubiquitin-mediated degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Inflammatory Mediators as Essential Elements in Bone Remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Pathogenesis of bone and cartilage destruction in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

E3 Ubiquitin Ligase Smurf1 Mediates Core-binding Factor α1/Runx2 Degradation and Plays A Specific Role in Osteoblast Differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Signalling pathways that mediate skeletal muscle hypertrophy and atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Disruption of Mekk2 in mice reveals an unexpected role for MEKK2 in modulating T-cell receptor signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Identification of ubiquitin ligases required for skeletal muscle atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Expression of vascular endothelial growth factor C and vascular endothelial growth factor receptor 3 in corneal lymphangiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Inhibition of osteoblast differentiation by tumor necrosis factor-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Advances in our understanding of the bone and joint pathology caused by Staphylococcus aureus infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun and JunD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Osteoblast programmed cell death (apoptosis): modulation by growth factors and cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Requirement for NF-kappaB in osteoclast and B-cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Induction of apoptosis in murine clonal osteoblasts expressed by human T-cell leukemia virus type I tax by NF-kappa B and TNF-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Effects of interleukin-1 beta and tumor necrosis factor-alpha on osteoblastic expression of osteocalcin and mineralized extracellular matrix in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

29 September 2017

Proinflammatory cytokines tumor necrosis factor-alpha and IL-6, but not IL-1, down-regulate the osteocalcin gene promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

27 June 2018

Expression of the osteoblast differentiation factor RUNX2 (Cbfa1/AML3/Pebp2alpha A) is inhibited by tumor necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709848200

21 January 2018

Systemic tumor necrosis factor alpha mediates an increase in peripheral CD11bhigh osteoclast precursors in tumor necrosis factor alpha-transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709848200

21 January 2018

Light-activated gene transduction of recombinant adeno-associated virus in human mesenchymal stem cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709848200

21 January 2018

Osteoporosis in the patients with rheumatoid arthritis (3) : the efficacy and the selection of the osteoporosis therapeutic drug

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517001

5 September 2018

Neuroendocrine Modulation Induced by Selective Blockade of TNF- in Rheumatoid Arthritis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709848200

21 January 2018

Ubiquitin-mediated degradation a mechanism for fine-tuning TGF-beta signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/18567580

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Balancing BMP Signaling through Integrated Inputs into the Smad1 Linker

1 reference

https://pubmed.ncbi.nlm.nih.gov/18567580

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor-alpha inhibits pre-osteoblast differentiation through its type-1 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18567580

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphological and mechanical properties of caudal vertebrae in the SAMP6 mouse model of senile osteoporosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18567580

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ceramide-induced nuclear translocation of NF-kappa B is a potential mediator of the apoptotic response to TNF-alpha in murine clonal osteoblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/18567580

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Therapy with anti-TNF antibodies in patients with Crohn disease]

1 reference

https://pubmed.ncbi.nlm.nih.gov/18567580

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M709848200

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

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