(Q36841614)

16 August 2017

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title

HIF-1 mediates the Warburg effect in clear cell renal carcinoma (English)

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16 August 2017

1

Gregg L Semenza

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16 August 2017

language of work or name

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1 June 2007

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Journal of Bioenergetics and Biomembranes

16 August 2017

published in

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16 August 2017

volume

39

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16 August 2017

issue

3

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16 August 2017

page(s)

231-234

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A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

16 August 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10863-007-9081-2

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

21 January 2018

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Reversion of transformed glycolysis to normal by inhibition of protein synthesis in rat kidney cells infected with temperature-sensitive mutant of Rous sarcoma virus

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12 December 2020

Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

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12 December 2020

Induction of HIF-1alpha in response to hypoxia is instantaneous

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12 December 2020

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

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12 December 2020

Proteomic identification of a role for the von Hippel Lindau tumour suppressor in changes in the expression of mitochondrial proteins and septin 2 in renal cell carcinoma

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12 December 2020

Glycolysis in chick embryo cell cultures transformed by Rous sarcoma virus

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12 December 2020

Why do cancers have high aerobic glycolysis?

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12 December 2020

Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway

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12 December 2020

Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

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12 December 2020

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

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12 December 2020

A conserved family of prolyl-4-hydroxylases that modify HIF

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12 December 2020

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

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12 December 2020

Purification and characterization of hypoxia-inducible factor 1

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12 December 2020

HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron

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12 December 2020

Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences

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12 December 2020

Temporal, spatial, and oxygen-regulated expression of hypoxia-inducible factor-1 in the lung

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12 December 2020

Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1.

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12 December 2020

Regulation of angiogenesis by hypoxia-inducible factor 1.

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12 December 2020

Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha

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12 December 2020

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

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12 December 2020

Hypoxic Regulation of Lactate Dehydrogenase A

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12 December 2020

Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

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12 December 2020

Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1

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12 December 2020

Proteomic changes in renal cancer and co-ordinate demonstration of both the glycolytic and mitochondrial aspects of the Warburg effect

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12 December 2020

Decrease of mitochondrial DNA content and energy metabolism in renal cell carcinoma

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12 December 2020

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

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12 December 2020

Low mitochondrial respiratory chain content correlates with tumor aggressiveness in renal cell carcinoma

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12 December 2020

Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways

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12 December 2020

Targeting HIF-1 for cancer therapy

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HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

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12 December 2020

HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

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12 December 2020

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1α

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12 December 2020

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

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12 December 2020

Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

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12 December 2020

Alterations in glucose metabolism in chick-embryo cells transformed by Rous sarcoma virus: intracellular levels of glycolytic intermediates

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12 December 2020

Mitochondrial disorders in renal tumors.

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12 December 2020

Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex

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12 December 2020

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

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12 December 2020

Prognostic factors for survival of patients with stage IV renal cell carcinoma: memorial sloan-kettering cancer center experience.

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12 December 2020

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

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12 December 2020

A new role for the von Hippel-Lindau tumor suppressor protein: stimulation of mitochondrial oxidative phosphorylation complex biogenesis

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12 December 2020

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

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12 December 2020

HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity

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12 December 2020

Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells.

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12 December 2020

Mechanical loading regulates expression of talin and its mRNA, which are concentrated at myotendinous junctions

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1007/S10863-007-9081-2

Identifiers

DOI

10.1007/S10863-007-9081-2

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16 August 2017

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