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A compass that points to lupus: genetic studies on type I interferon pathway.
scientific article published on 21 June 2007
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Europe PubMed Central
PubMed ID
17581625
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17581625%20AND%20SRC:MED&resulttype=core&format=json
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1 January 2020
review article
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Europe PubMed Central
title
A compass that points to lupus: genetic studies on type I interferon pathway
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
17581625
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17581625%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
author
Naoyuki Tsuchiya
series ordinal
2
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Europe PubMed Central
PubMed ID
17581625
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1 January 2020
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Kyogoku C
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1
1 reference
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Europe PubMed Central
PubMed ID
17581625
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1 January 2020
publication date
21 June 2007
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Europe PubMed Central
PubMed ID
17581625
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1 January 2020
published in
Genes and Immunity
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Europe PubMed Central
PubMed ID
17581625
reference URL
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retrieved
1 January 2020
volume
8
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Europe PubMed Central
PubMed ID
17581625
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17581625%20AND%20SRC:MED&resulttype=core&format=json
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1 January 2020
issue
6
1 reference
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Europe PubMed Central
PubMed ID
17581625
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17581625%20AND%20SRC:MED&resulttype=core&format=json
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1 January 2020
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445-455
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Europe PubMed Central
PubMed ID
17581625
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1 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/sj.gene.6364409
0 references
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The combination of apoptotic U937 cells and lupus IgG is a potent IFN-alpha inducer
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Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
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The interferon-inducible p202 protein as a modulator of transcription: inhibition of NF-kappa B, c-Fos, and c-Jun activities
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21 January 2018
Immune Interferon in the Circulation of Patients with Autoimmune Disease
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Serum interferon levels in patients with systemic lupus erythematosus
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Systemic lupus erythematosus: presence in human serum of an unusual acid-labile leukocyte interferon
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Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies
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Antibodies against double-stranded DNA and development of polymyositis during treatment with interferon
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Autoimmune Phenomena in Patients with Malignant Carcinoid Tumors During Interferon-α Treatment
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Induction of clinical autoimmune disease by therapeutic interferon-alpha
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Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.
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A RUNX trio with a taste for autoimmunity
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Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
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Interferon and granulopoiesis signatures in systemic lupus erythematosus blood
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Coordinate overexpression of interferon-alpha-induced genes in systemic lupus erythematosus
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Elevated serum levels of interferon-regulated chemokines are biomarkers for active human systemic lupus erythematosus
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Virus interference. I. The interferon
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Type I interferons (alpha/beta) in immunity and autoimmunity
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Neutralizing interferon alpha as a therapeutic approach to autoimmune diseases
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A road map for those who don't know JAK-STAT
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High levels of circulating early apoptic peripheral blood mononuclear cells in systemic lupus erythematosus
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Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus.
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Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes
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Patients with systemic lupus erythematosus (SLE) have a circulating inducer of interferon-alpha (IFN-alpha) production acting on leucocytes resembling immature dendritic cells
1 reference
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7 January 2021
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Activation of natural interferon-alpha producing cells by apoptotic U937 cells combined with lupus IgG and its regulation by cytokines
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7 January 2021
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Importance of CpG dinucleotides in activation of natural IFN-alpha-producing cells by a lupus-related oligodeoxynucleotide
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A pivotal role for the natural interferon alpha-producing cells (plasmacytoid dendritic cells) in the pathogenesis of lupus
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Fc gamma RIIa is expressed on natural IFN-alpha-producing cells (plasmacytoid dendritic cells) and is required for the IFN-alpha production induced by apoptotic cells combined with lupus IgG
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Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6
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7 January 2021
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A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
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TLR signaling
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Innate immune recognition of viral infection
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7 January 2021
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Toll-like receptor control of the adaptive immune responses
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IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors
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Plasmacytoid dendritic cells in immunity
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Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8
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A Toll-like receptor recognizes bacterial DNA
1 reference
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Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
1 reference
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7 January 2021
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Polyclonal B-cell activation of autoantibodies (CBA/N x NZB)F1 mice by polyinosinic polycytidylic acid
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7 January 2021
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Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice
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7 January 2021
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Type I Interferon controls the onset and severity of autoimmune manifestations in lpr mice
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7 January 2021
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Inhibition of lupus by genetic alteration of the interferon-alpha/beta receptor
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7 January 2021
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Dichotomic effects of IFN-gamma on the development of systemic lupus erythematosus-like syndrome in MRL-lpr / lpr mice
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Interferon-gamma is required for lupus nephritis in mice treated with the hydrocarbon oil pristane
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7 January 2021
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Treatment of murine lupus with cDNA encoding IFN-gammaR/Fc
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the interferon-alpha pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease.
1 reference
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7 January 2021
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Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus
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7 January 2021
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Analysis of gene expression profiles in human systemic lupus erythematosus using oligonucleotide microarray
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7 January 2021
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Microarray analysis of gene expression in lupus
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7 January 2021
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Protein interaction for an interferon-inducible systemic lupus associated gene, IFIT1.
1 reference
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7 January 2021
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Gene expression profiling in human autoimmunity.
1 reference
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7 January 2021
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The emerging role of interferon in human systemic lupus erythematosus
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7 January 2021
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Optimization of Rolling-Circle Amplified Protein Microarrays for Multiplexed Protein Profiling
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7 January 2021
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Development and standardization of multiplexed antibody microarrays for use in quantitative proteomics
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7 January 2021
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Derivation of the SLEDAI. A disease activity index for lupus patients. The Committee on Prognosis Studies in SLE.
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Reliability and validity of six systems for the clinical assessment of disease activity in systemic lupus erythematosus
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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
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7 January 2021
based on heuristic
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A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
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7 January 2021
based on heuristic
inferred from DOI database lookup
Fcgamma receptor gene polymorphisms in Japanese patients with systemic lupus erythematosus: contribution of FCGR2B to genetic susceptibility
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of Fc gamma receptor IIb polymorphism in the genetic background of systemic lupus erythematosus: insights from Asia
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
FcgammaRIIB Ile232Thr transmembrane polymorphism associated with human systemic lupus erythematosus decreases affinity to lipid rafts and attenuates inhibitory effects on B cell receptor signaling.
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
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7 January 2021
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Role of B cell inhibitory receptor polymorphisms in systemic lupus erythematosus: a negative times a negative makes a positive.
1 reference
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7 January 2021
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Association of a common complement receptor 2 haplotype with increased risk of systemic lupus erythematosus
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus
1 reference
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reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
IFNs and STATs in innate immunity to microorganisms
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
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7 January 2021
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IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors
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7 January 2021
based on heuristic
inferred from DOI database lookup
Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
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7 January 2021
based on heuristic
inferred from DOI database lookup
IRF family of transcription factors as regulators of host defense
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
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7 January 2021
based on heuristic
inferred from DOI database lookup
Comparative analysis of IRF and IFN-alpha expression in human plasmacytoid and monocyte-derived dendritic cells
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
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7 January 2021
based on heuristic
inferred from DOI database lookup
Two discrete promoters regulate the alternatively spliced human interferon regulatory factor-5 isoforms. Multiple isoforms with distinct cell type-specific expression, localization, regulation, and function
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
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7 January 2021
based on heuristic
inferred from DOI database lookup
Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9.
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
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7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus
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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
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7 January 2021
based on heuristic
inferred from DOI database lookup
Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes.
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
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7 January 2021
based on heuristic
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Regulation of the type I IFN induction: a current view
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Negative regulation of Toll-like-receptor signaling by IRF-4.
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
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7 January 2021
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inferred from DOI database lookup
Multiple regulatory domains of IRF-5 control activation, cellular localization, and induction of chemokines that mediate recruitment of T lymphocytes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
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7 January 2021
based on heuristic
inferred from DOI database lookup
The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
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7 January 2021
based on heuristic
inferred from DOI database lookup
Virus-induced heterodimer formation between IRF-5 and IRF-7 modulates assembly of the IFNA enhanceosome in vivo and transcriptional activity of IFNA genes
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
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7 January 2021
based on heuristic
inferred from DOI database lookup
Global and distinct targets of IRF-5 and IRF-7 during innate response to viral infection
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
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7 January 2021
based on heuristic
inferred from DOI database lookup
Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis
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7 January 2021
based on heuristic
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Genetic modifiers of systemic lupus erythematosus in FcgammaRIIB(-/-) mice
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7 January 2021
based on heuristic
inferred from DOI database lookup
A y chromosome associated factor in strain bxsb producing accelerated autoimmunity and lymphoproliferation
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7 January 2021
based on heuristic
inferred from DOI database lookup
Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication
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7 January 2021
based on heuristic
inferred from DOI database lookup
A Tlr7 translocation accelerates systemic autoimmunity in murine lupus
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7 January 2021
based on heuristic
inferred from DOI database lookup
Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural insertion/deletion variation in IRF5 is associated with a risk haplotype and defines the precise IRF5 isoforms expressed in systemic lupus erythematosus.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic analysis of genome-wide variation in human gene expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mapping determinants of human gene expression by regional and genome-wide association
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A haplotype map of the human genome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The 3' untranslated region of messenger RNA: A molecular 'hotspot' for pathology?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A history of poly A sequences: from formation to factors to function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Translational control by CPEB: a means to the end
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of IRF5 in UK SLE families identifies a variant involved in polyadenylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ICSBP/IRF-8 transactivation: a tale of protein-protein interaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Systemic lupus erythematosus: all roads lead to type I interferons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Type I interferon in systemic lupus erythematosus and other autoimmune diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Replication of the genetic effects of IFN regulatory factor 5 (IRF5) on systemic lupus erythematosus in a Korean population
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A human genome diversity cell line panel
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of IRF-4-binding protein leads to the spontaneous development of systemic autoimmunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Roles of genetic variations in signalling/immunoregulatory molecules in susceptibility to systemic lupus erythematosus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.GENE.6364409
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.GENE.6364409
1 reference
stated in
Europe PubMed Central
PubMed ID
17581625
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17581625%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
PubMed ID
17581625
1 reference
stated in
Europe PubMed Central
PubMed ID
17581625
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17581625%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
ResearchGate publication ID
6254904
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