(Q36863949)

English

Local administration of TLR ligands rescues the function of tumor-infiltrating CD8 T cells and enhances the antitumor effect of lentivector immunization

scientific article published on 22 April 2013

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scholarly article

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Europe PubMed Central

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29 February 2020

Local administration of TLR ligands rescues the function of tumor-infiltrating CD8 T cells and enhances the antitumor effect of lentivector immunization (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23610140%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

toll-like receptor

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8

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29 February 2020

David L Bartlett

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David L Bartlett

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29 February 2020

author name string

Haiyan Xiao

1

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29 February 2020

Yibing Peng

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29 February 2020

Yuan Hong

3

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29 February 2020

Lei Huang

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29 February 2020

Z Sheng Guo

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29 February 2020

Ning Fu

7

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29 February 2020

Andrew Mellor

9

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29 February 2020

Yukai He

10

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29 February 2020

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22 April 2013

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29 February 2020

Journal of Immunology

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29 February 2020

190

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29 February 2020

11

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29 February 2020

5866-5873

1 reference

Europe PubMed Central

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29 February 2020

Engineering DNA nanoparticles as immunomodulatory reagents that activate regulatory T cells

1 reference

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29 September 2017

Immunoglobulin Fc fragment tagging allows strong activation of endogenous CD4 T cells to reshape the tumor milieu and enhance the antitumor effect of lentivector immunization

1 reference

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Ovarian cancer progression is controlled by phenotypic changes in dendritic cells

1 reference

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29 September 2017

TLR2 signaling depletes IRAK1 and inhibits induction of type I IFN by TLR7/9.

1 reference

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29 September 2017

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1 reference

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29 September 2017

Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cells

1 reference

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29 September 2017

Lentivector prime and vaccinia virus vector boost generate high-quality CD8 memory T cells and prevent autochthonous mouse melanoma

1 reference

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29 September 2017

Exhaustion of tumor-specific CD8⁺ T cells in metastases from melanoma patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3660440

29 September 2017

Combination of lentivector immunization and low-dose chemotherapy or PD-1/PD-L1 blocking primes self-reactive T cells and induces anti-tumor immunity

1 reference

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29 September 2017

CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans

1 reference

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29 September 2017

Lentivector expressing HBsAg and immunoglobulin Fc fusion antigen induces potent immune responses and results in seroconversion in HBsAg transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3660440

29 September 2017

The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity

1 reference

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29 September 2017

Blockade of programmed death-1 pathway rescues the effector function of tumor-infiltrating T cells and enhances the antitumor efficacy of lentivector immunization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3660440

29 September 2017

Tumor-resident CD8+ T-cell: the critical catalyst in IL-12-mediated reversal of tumor immune suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3660440

29 September 2017

Cutting edge: delay and reversal of T cell tolerance by intratumoral injection of antigen-loaded dendritic cells in an autochthonous tumor model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3660440

29 September 2017

Toll-like receptor 3-mediated suppression of TRAMP prostate cancer shows the critical role of type I interferons in tumor immune surveillance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3660440

29 September 2017

Cutting edge: the Th1 response inhibits the generation of peripheral regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3660440

29 September 2017

Dendritic cell recovery post-lymphodepletion: a potential mechanism for anti-cancer adoptive T cell therapy and vaccination

1 reference

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29 September 2017

Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3660440

29 September 2017

Lentivector immunization stimulates potent CD8 T cell responses against melanoma self-antigen tyrosinase-related protein 1 and generates antitumor immunity in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3660440

29 September 2017

Melanoma progression despite infiltration by in vivo-primed TRP-2-specific T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3660440

29 September 2017

T-cell modulation combined with intratumoral CpG cures lymphoma in a mouse model without the need for chemotherapy

1 reference

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29 September 2017

Cancer immunotherapy by dendritic cells

1 reference

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29 September 2017

Rapid tolerization of virus-activated tumor-specific CD8+ T cells in prostate tumors of TRAMP mice

1 reference

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29 September 2017

Cancer-related inflammation

1 reference

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29 September 2017

Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs

1 reference

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29 September 2017

Targeting the effector site with IFN-alphabeta-inducing TLR ligands reactivates tumor-resident CD8 T cell responses to eradicate established solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3660440

29 September 2017

Antagonistic nature of T helper 1/2 developmental programs in opposing peripheral induction of Foxp3+ regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3660440

29 September 2017

Failure at the effector phase: immune barriers at the level of the melanoma tumor microenvironment

1 reference

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29 September 2017

Plasmid DNA and viral vector-based vaccines for the treatment of cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3660440

29 September 2017

Development of TLR9 agonists for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3660440

29 September 2017

A cytokine-mediated link between innate immunity, inflammation, and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3660440

29 September 2017

Recombinant viral vectors: cancer vaccines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3660440

29 September 2017

CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3660440

29 September 2017

Skin-derived dendritic cells induce potent CD8(+) T cell immunity in recombinant lentivector-mediated genetic immunization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3660440

29 September 2017

Regulatory T cells, tumour immunity and immunotherapy

1 reference

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29 September 2017

Effector-phase tolerance: another mechanism of how cancer escapes antitumor immune response

1 reference

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29 September 2017

Restoring function in exhausted CD8 T cells during chronic viral infection

1 reference

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29 September 2017

Induction of effective therapeutic antitumor immunity by direct in vivo administration of lentiviral vectors

1 reference

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29 September 2017

Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection

1 reference

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29 September 2017

Type I interferon dependence of plasmacytoid dendritic cell activation and migration.

1 reference

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29 September 2017

T-cell epitope peptide vaccines.

1 reference

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29 September 2017

Cancer immunotherapy: moving beyond current vaccines

1 reference

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29 September 2017

Quiescent phenotype of tumor-specific CD8+ T cells following immunization

1 reference

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Intravenous injection of a lentiviral vector encoding NY-ESO-1 induces an effective CTL response

1 reference

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29 September 2017

Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells.

1 reference

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29 September 2017

In vivo administration of a lentiviral vaccine targets DCs and induces efficient CD8(+) T cell responses

1 reference

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29 September 2017

Critical role for alpha/beta and gamma interferons in persistence of lymphocytic choriomeningitis virus by clonal exhaustion of cytotoxic T cells

1 reference

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Viral immune evasion due to persistence of activated T cells without effector function

1 reference

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Injection of IL-12 gene-transduced dendritic cells into mouse liver tumor lesions activates both innate and acquired immunity

1 reference

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1 reference

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1 reference

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4 September 2018

Immunization with lentiviral vector-transduced dendritic cells induces strong and long-lasting T cell responses and therapeutic immunity

1 reference

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4 September 2018

Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease

1 reference

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4 September 2018

Dendritic Cell-Induced Memory T Cell Activation in Nonlymphoid Tissues

1 reference

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4 December 2018

Lymphoma immunotherapy with CpG oligodeoxynucleotides requires TLR9 either in the host or in the tumor itself

1 reference

https://pubmed.ncbi.nlm.nih.gov/23610140

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An inflammatory link

1 reference

https://pubmed.ncbi.nlm.nih.gov/23610140

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A convenient microassay for cytolysis and cytostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23610140

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Toll-like trigger for autoimmune disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23610140

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.1203470

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Europe PubMed Central

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29 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23610140%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

Europe PubMed Central

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29 February 2020

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