(Q36864001)

English

Cannabidiol Counteracts Amphetamine-Induced Neuronal and Behavioral Sensitization of the Mesolimbic Dopamine Pathway through a Novel mTOR/p70S6 Kinase Signaling Pathway

scientific article published on May 2016

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scholarly article

1 reference

Europe PubMed Central

16 August 2017

Cannabidiol Counteracts Amphetamine-Induced Neuronal and Behavioral Sensitization of the Mesolimbic Dopamine Pathway through a Novel mTOR/p70S6 Kinase Signaling Pathway (English)

1 reference

Europe PubMed Central

16 August 2017

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object named as

Laura G Rosen

3

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Michael Loureiro

object named as

Michael Loureiro

2

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object named as

Susanne Schmid

6

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author name string

Justine Renard

1

1 reference

Europe PubMed Central

16 August 2017

Jordan Zunder

4

1 reference

Europe PubMed Central

16 August 2017

Cleusa de Oliveira

5

1 reference

Europe PubMed Central

16 August 2017

Walter J Rushlow

7

1 reference

Europe PubMed Central

16 August 2017

Steven R Laviolette

8

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Europe PubMed Central

16 August 2017

language of work or name

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publication date

1 May 2016

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Europe PubMed Central

16 August 2017

Journal of Neuroscience

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Europe PubMed Central

16 August 2017

36

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Europe PubMed Central

16 August 2017

18

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Europe PubMed Central

16 August 2017

5160-5169

1 reference

Europe PubMed Central

16 August 2017

Hippocampal cannabinoid transmission modulates dopamine neuron activity: impact on rewarding memory formation and social interaction

1 reference

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Long-term consequences of adolescent cannabinoid exposure in adult psychopathology

1 reference

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Functional variants in DPYSL2 sequence increase risk of schizophrenia and suggest a link to mTOR signaling

1 reference

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1 reference

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29 September 2017

Amphetamine sensitization alters reward processing in the human striatum and amygdala.

1 reference

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Is the mTOR-signalling cascade disrupted in Schizophrenia?

1 reference

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Delta-9-tetrahydrocannabinol-induced dopamine release as a function of psychosis risk: 18F-fallypride positron emission tomography study

1 reference

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Cannabidiol inhibits THC-elicited paranoid symptoms and hippocampal-dependent memory impairment

1 reference

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Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia

1 reference

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Chronic Δ⁹-tetrahydrocannabinol exposure induces a sensitization of dopamine D₂/₃ receptors in the mesoaccumbens and nigrostriatal systems.

1 reference

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Are you or aren't you? Challenges associated with physiologically identifying dopamine neurons

1 reference

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Haloperidol regulates the state of phosphorylation of ribosomal protein S6 via activation of PKA and phosphorylation of DARPP-32

1 reference

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The mTOR signaling pathway in the prefrontal cortex is compromised in major depressive disorder

1 reference

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mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists

1 reference

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29 September 2017

Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1).

1 reference

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Does dopamine mediate the psychosis-inducing effects of cannabis? A review and integration of findings across disciplines

1 reference

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mTOR signaling: at the crossroads of plasticity, memory and disease

1 reference

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Opposite effects of delta-9-tetrahydrocannabinol and cannabidiol on human brain function and psychopathology

1 reference

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Roles of the Akt/GSK-3 and Wnt signaling pathways in schizophrenia and antipsychotic drug action

1 reference

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What is the mechanism whereby cannabis use increases risk of psychosis?

1 reference

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Schizophrenia: a concise overview of incidence, prevalence, and mortality

1 reference

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29 September 2017

Activation of the canonical Wnt pathway by the antipsychotics haloperidol and clozapine involves dishevelled-3

1 reference

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29 September 2017

Risk factors for schizophrenia--all roads lead to dopamine

1 reference

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29 September 2017

Cannabidiol reverses MK-801-induced disruption of prepulse inhibition in mice

1 reference

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Mechanisms of action of second generation antipsychotic drugs in schizophrenia: insights from brain imaging studies

1 reference

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Impact of atypical antipsychotics on quality of life in patients with schizophrenia

1 reference

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The Psychotomimetic Effects of Intravenous Delta-9-Tetrahydrocannabinol in Healthy Individuals: Implications for Psychosis

1 reference

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Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review

1 reference

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Antidepressant effects of ketamine in depressed patients

1 reference

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Comparison of dopamine receptor antagonists on hyperlocomotion induced by cocaine, amphetamine, MK-801 and the dopamine D1 agonist C-APB in mice

1 reference

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Sensorimotor gating and schizophrenia. Human and animal model studies

1 reference

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Removal of S6K1 and S6K2 leads to divergent alterations in learning, memory, and synaptic plasticity.

1 reference

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27 June 2018

Withdrawal from repeated amphetamine administration leads to disruption of prepulse inhibition but not to disruption of latent inhibition

1 reference

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Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia

1 reference

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Neurochemical sensitization in the pathophysiology of schizophrenia: deficits and dysfunction in neuronal regulation and plasticity

1 reference

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Time course of extracellular dopamine and behavioral sensitization to cocaine. II. Dopamine perikarya.

1 reference

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Intracellular and extracellular electrophysiology of nigral dopaminergic neurons--1. Identification and characterization.

1 reference

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Adolescent Cannabinoid Exposure Induces a Persistent Sub-Cortical Hyper-Dopaminergic State and Associated Molecular Adaptations in the Prefrontal Cortex.

1 reference

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Amphetamine sensitisation and memory in healthy human volunteers: a functional magnetic resonance imaging study

1 reference

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1 reference

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Clozapine pre-treatment has a protracted hypolocomotor effect on the induction and expression of amphetamine sensitization.

1 reference

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Haloperidol promotes mTORC1-dependent phosphorylation of ribosomal protein S6 via dopamine- and cAMP-regulated phosphoprotein of 32 kDa and inhibition of protein phosphatase-1.

1 reference

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1 reference

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Effect of cannabidiol in a MK-801-rodent model of aspects of schizophrenia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854973

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Axonal branching patterns of nucleus accumbens neurons in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854973

4 September 2018

Effects of neonatal MK-801 treatment on p70S6K-S6/eIF4B signal pathways and protein translation in the frontal cortex of the developing rat brain

1 reference

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Amphetamine sensitization in rats as an animal model of schizophrenia

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Cannabidiol inhibits the hyperlocomotion induced by psychotomimetic drugs in mice

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Antipsychotics alter the protein expression levels of beta-catenin and GSK-3 in the rat medial prefrontal cortex and striatum

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Uniform inhibition of dopamine neurons in the ventral tegmental area by aversive stimuli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854973

4 September 2018

Amphetamine-sensitized animals show a sensorimotor gating and neurochemical abnormality similar to that of schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854973

4 September 2018

Clozapine and haloperidol block the induction of behavioral sensitization to amphetamine and associated genomic responses in rats.

1 reference

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4 September 2018

Efferent projections of the nucleus accumbens in the rat with special reference to subdivision of the nucleus: biotinylated dextran amine study.

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4 September 2018

Expression of D1 receptor, D2 receptor, substance P and enkephalin messenger RNAs in the neurons projecting from the nucleus accumbens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854973

4 September 2018

Electrophysiological effects of cocaine in the mesoaccumbens dopamine system: studies in the ventral tegmental area.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4854973

4 September 2018

Projections from the rat prefrontal cortex to the ventral tegmental area: target specificity in the synaptic associations with mesoaccumbens and mesocortical neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/27147666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of endogenous sensitization in the pathophysiology of schizophrenia: implications from recent brain imaging studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/27147666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A circuitry model of the expression of behavioral sensitization to amphetamine-like psychostimulants

1 reference

https://pubmed.ncbi.nlm.nih.gov/27147666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Feedback control of mesolimbic somatodendritic dopamine release in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/27147666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of cannabidiol in animal models predictive of antipsychotic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/27147666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.3387-15.2016

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

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