(Q36883347)

English

Rationale, design and baseline characteristics of a large, simple, randomized trial of combined folic acid and vitamins B6 and B12 in high-risk patients: the Heart Outcomes Prevention Evaluation (HOPE)-2 trial

scientific article published on January 2006

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

Rationale, design and baseline characteristics of a large, simple, randomized trial of combined folic acid and vitamins B6 and B12 in high-risk patients: the Heart Outcomes Prevention Evaluation (HOPE)-2 trial (English)

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

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C Held

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Europe PubMed Central

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16 August 2017

Jeffrey L Probstfield

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J Probstfield

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Europe PubMed Central

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16 August 2017

author name string

E Lonn

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Europe PubMed Central

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16 August 2017

J M O Arnold

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16 August 2017

M McQueen

5

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Europe PubMed Central

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16 August 2017

M Micks

6

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Europe PubMed Central

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16 August 2017

J Pogue

7

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Europe PubMed Central

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16 August 2017

P Sheridan

8

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Europe PubMed Central

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16 August 2017

J Bosch

9

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Europe PubMed Central

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16 August 2017

J Genest

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16 August 2017

S Yusuf

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16 August 2017

HOPE-2 Investigators

12

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16 August 2017

publication date

1 January 2006

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Europe PubMed Central

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16 August 2017

The Canadian Journal of Cardiology

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16 August 2017

22

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16 August 2017

1

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16 August 2017

47-53

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Europe PubMed Central

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16 August 2017

Homocysteine-lowering trials for prevention of cardiovascular events: a review of the design and power of the large randomized trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538982

29 September 2017

Angiotensin-converting-enzyme inhibition in stable coronary artery disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538982

29 September 2017

The Women's Antioxidant Cardiovascular Study: design and baseline characteristics of participants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538982

29 September 2017

Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538982

29 September 2017

MTHFR 677C-->T polymorphism and risk of coronary heart disease: a meta-analysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538982

29 September 2017

Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538982

29 September 2017

The VITATOPS (Vitamins to Prevent Stroke) Trial: rationale and design of an international, large, simple, randomised trial of homocysteine-lowering multivitamin therapy in patients with recent transient ischaemic attack or stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538982

29 September 2017

Homocyst(e)ine and cardiovascular disease: a critical review of the epidemiologic evidence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538982

29 September 2017

Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538982

29 September 2017

The metabolism of homocysteine: pathways and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538982

29 September 2017

A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538982

29 September 2017

The natural history of homocystinuria due to cystathionine beta-synthase deficiency.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538982

29 September 2017

Intensive lipid lowering with atorvastatin in patients with stable coronary disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538982

4 September 2018

Folate therapy and in-stent restenosis after coronary stenting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538982

4 September 2018

Background and rationale of the SU.FOL.OM3 study: double-blind randomized placebo-controlled secondary prevention trial to test the impact of supplementation with folate, vitamin B6 and B12 and/or omega-3 fatty acids on the prevention of recurrent i

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538982

4 September 2018

Secondary prevention with folic acid: effects on clinical outcomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538982

4 September 2018

Total homocysteine lowering treatment among coronary artery disease patients in the era of folic acid-fortified cereal grain flour

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538982

4 September 2018

Folic acid improves endothelial function in coronary artery disease via mechanisms largely independent of homocysteine lowering

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538982

4 September 2018

Decreased rate of coronary restenosis after lowering of plasma homocysteine levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538982

4 September 2018

Folic Acid Reverts Dysfunction of Endothelial Nitric Oxide Synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16450017

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homocystinemia. Vascular injury and arterial thrombosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16450017

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homocysteine theory of arteriosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16450017

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of sulfinpyrazone on homocysteine-induced endothelial injury and arteriosclerosis in baboons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16450017

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperhomocysteinemia: an independent risk factor for vascular disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16450017

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Quantitative Assessment of Plasma Homocysteine as a Risk Factor for Vascular Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16450017

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-Methyltetrahydrofolate, the Active Form of Folic Acid, Restores Endothelial Function in Familial Hypercholesterolemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16450017

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homocysteine and atherothrombosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16450017

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lowering blood homocysteine with folic acid based supplements: meta-analysis of randomised trials. Homocysteine Lowering Trialists' Collaboration

1 reference

https://pubmed.ncbi.nlm.nih.gov/16450017

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of folic acid fortification on plasma folate and total homocysteine concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/16450017

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heterozygosity for Homocystinuria in Premature Peripheral and Cerebral Occlusive Arterial Disease

1 reference

https://api.crossref.org/works/10.1016%2FS0828-282X%2806%2970238-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0828-282X(06)70238-0

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

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