(Q36890646)

English

12/15-Lipoxygenase mediates high-fat diet-induced endothelial tight junction disruption and monocyte transmigration: a new role for 15(S)-hydroxyeicosatetraenoic acid in endothelial cell dysfunction

scientific article published on 15 April 2013

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scholarly article

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28 February 2020

12/15-Lipoxygenase mediates high-fat diet-induced endothelial tight junction disruption and monocyte transmigration: a new role for 15(S)-hydroxyeicosatetraenoic acid in endothelial cell dysfunction (English)

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28 February 2020

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Venkatesh Kundumani-Sridharan

1

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28 February 2020

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Elena Dyukova

2

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28 February 2020

Dale E Hansen

3

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28 February 2020

Gadiparthi N Rao

4

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15 April 2013

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28 February 2020

Journal of Biological Chemistry

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28 February 2020

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28 February 2020

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28 February 2020

15830-15842

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28 February 2020

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1 reference

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12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet

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Control of oxygenation in lipoxygenase and cyclooxygenase catalysis

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Protein phosphatases 2A and 1 interact with occludin and negatively regulate the assembly of tight junctions in the CACO-2 cell monolayer

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Depletion of E-cadherin disrupts establishment but not maintenance of cell junctions in Madin-Darby canine kidney epithelial cells

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ESAM supports neutrophil extravasation, activation of Rho, and VEGF-induced vascular permeability

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29 September 2017

Signaling mechanisms regulating endothelial permeability

1 reference

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29 September 2017

12/15-lipoxygenase regulates intercellular adhesion molecule-1 expression and monocyte adhesion to endothelium through activation of RhoA and nuclear factor-kappaB.

1 reference

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Inflammation, atherosclerosis, and coronary artery disease

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Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis

1 reference

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New risk factors for atherosclerosis and patient risk assessment

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29 September 2017

Endothelial cell-cell junctions: happy together

1 reference

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29 September 2017

Increased Production of 12/15 Lipoxygenase Eicosanoids Accelerates Monocyte/Endothelial Interactions in Diabetic db/db Mice

1 reference

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29 September 2017

Signalling to and from tight junctions

1 reference

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29 September 2017

Low density lipoprotein receptor-related protein-mediated membrane translocation of 12/15-lipoxygenase is required for oxidation of low density lipoprotein by macrophages

1 reference

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29 September 2017

Atherosclerotic lesions grow through recruitment and proliferation of circulating monocytes in a murine model

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29 September 2017

Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins

1 reference

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Endothelial claudin: claudin-5/TMVCF constitutes tight junction strands in endothelial cells

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Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice

1 reference

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The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy

1 reference

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Overexpression, purification and characterization of human recombinant 15-lipoxygenase

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Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man

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Role of oxidized low density lipoprotein in atherogenesis

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1 reference

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27 June 2018

Fibroblasts that overexpress 15-lipoxygenase generate bioactive and minimally modified LDL.

1 reference

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Attenuation of diet-induced atherosclerosis in rabbits with a highly selective 15-lipoxygenase inhibitor lacking significant antioxidant properties

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A leukocyte type of 12-lipoxygenase is expressed in human vascular and mononuclear cells. Evidence for upregulation by angiotensin II.

1 reference

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Induction of 15-lipoxygenase mRNA and protein in early atherosclerotic lesions

1 reference

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27 June 2018

Lipoxygenase-mediated transformation of human low density lipoprotein to an oxidized and cytotoxic complex.

1 reference

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Hypercholesterolemia enhances 15-lipoxygenase-mediated vasorelaxation and acetylcholine-induced hypotension

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1 reference

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Lipoxygenase pathways as mediators of early inflammatory events in atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23589307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of 15-lipoxygenase in vascular endothelium accelerates early atherosclerosis in LDL receptor-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23589307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperlipidemia and atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23589307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of 15-HETE as a major hydroxyeicosatetraenoic acid in the atherosclerotic vessel wall

1 reference

https://pubmed.ncbi.nlm.nih.gov/23589307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M113.453290

1 reference

Europe PubMed Central

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28 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23589307%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23589307%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

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