(Q36890842)

16 August 2017

Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans (English)

1 reference

16 August 2017

14

Detlef Schuppan

1 reference

16 August 2017

Alessia Omenetti

1

1 reference

16 August 2017

Alessandro Porrello

2

1 reference

16 August 2017

Youngmi Jung

3

1 reference

16 August 2017

Liu Yang

4

1 reference

16 August 2017

Yury Popov

5

1 reference

16 August 2017

Steve S Choi

6

1 reference

16 August 2017

Rafal P Witek

7

1 reference

16 August 2017

Gianfranco Alpini

8

1 reference

16 August 2017

Juliet Venter

9

1 reference

16 August 2017

Hendrika M Vandongen

10

1 reference

16 August 2017

Wing-Kin Syn

11

1 reference

16 August 2017

Gianluca Svegliati Baroni

12

1 reference

16 August 2017

Antonio Benedetti

13

1 reference

16 August 2017

Anna Mae Diehl

15

1 reference

16 August 2017

language of work or name

English

0 references

publication date

1 October 2008

1 reference

Journal of Clinical Investigation

16 August 2017

1 reference

16 August 2017

118

1 reference

16 August 2017

10

1 reference

16 August 2017

3331-3342

1 reference

describes a project that uses

16 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2542850/fullTextXML

inferred from PubMed Central ID database lookup

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29 September 2017

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29 September 2017

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29 September 2017

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Mice with a targeted mutation of patched2 are viable but develop alopecia and epidermal hyperplasia

29 September 2017

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29 September 2017

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Hepatocyte growth factor attenuates liver fibrosis induced by bile duct ligation

29 September 2017

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The epithelial-mesenchymal transition: new insights in signaling, development, and disease

29 September 2017

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Complex networks orchestrate epithelial-mesenchymal transitions

29 September 2017

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Hedgehog signaling maintains resident hepatic progenitors throughout life

29 September 2017

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29 September 2017

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Role for hedgehog signaling in hepatic stellate cell activation and viability

29 September 2017

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Snail induction is an early response to Gli1 that determines the efficiency of epithelial transformation

29 September 2017

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Molecular requirements for epithelial-mesenchymal transition during tumor progression

29 September 2017

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Wnt, hedgehog and snail: sister pathways that control by GSK-3beta and beta-Trcp in the regulation of metastasis

29 September 2017

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Inducible nitric oxide synthase up-regulates Notch-1 in mouse cholangiocytes: implications for carcinogenesis

29 September 2017

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Portal fibroblasts regulate the proliferation of bile duct epithelia via expression of NTPDase2.

29 September 2017

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29 September 2017

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29 September 2017

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Tissue repair and stem cell renewal in carcinogenesis

29 September 2017

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The cholangiopathies: disorders of biliary epithelia

29 September 2017

1 reference

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An in vivo comparative study of sonic, desert and Indian hedgehog reveals that hedgehog pathway activity regulates epidermal stem cell homeostasis

29 September 2017

1 reference

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Hedgehog signalling in prostate regeneration, neoplasia and metastasis

29 September 2017

1 reference

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NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression

29 September 2017

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Liver regeneration and repair: hepatocytes, progenitor cells, and stem cells

29 September 2017

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Origin and characterization of a human bipotent liver progenitor cell line

29 September 2017

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Hedgehog signalling in cancer formation and maintenance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Epithelial-mesenchymal transition and its implications for fibrosis

29 September 2017

1 reference

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Epithelial-mesenchymal transitions in development and pathologies

29 September 2017

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Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

29 September 2017

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Identifying biological themes within lists of genes with EASE

29 September 2017

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Exploration, normalization, and summaries of high density oligonucleotide array probe level data

29 September 2017

1 reference

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CRIM1 regulates the rate of processing and delivery of bone morphogenetic proteins to the cell surface.

29 September 2017

1 reference

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Reciprocal modulation of matrix metalloproteinase-13 and type I collagen genes in rat hepatic stellate cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

DAVID: Database for Annotation, Visualization, and Integrated Discovery

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Summaries of Affymetrix GeneChip probe level data

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lung

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Hepatic progenitor cells in human liver diseases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Evidence that fibroblasts derive from epithelium during tissue fibrosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Pentoxifylline downregulates profibrogenic cytokines and procollagen I expression in rat secondary biliary fibrosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Creating the gene ontology resource: design and implementation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Transducing the hedgehog signal

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Inhibition of MMH (Met murine hepatocyte) cell differentiation by TGF(beta) is abrogated by pre-treatment with the heritable differentiation effector FGF1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Pathological relevance of epithelial and mesenchymal phenotype plasticity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Early role of Fsp1 in epithelial-mesenchymal transformation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Altered neural cell fates and medulloblastoma in mouse patched mutants

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Identification and characterization of a fibroblast marker: FSP1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Hepatic lipocytes: the principal collagen-producing cells of normal rat liver

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Biliary physiology in rats with bile ductular cell hyperplasia. Evidence for a secretory function of proliferated bile ductules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Glucagon-like peptide-1 and its receptor agonist exendin-4 modulate cholangiocyte adaptive response to cholestasis

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Patched2 modulates tumorigenesis in patched1 heterozygous mice

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

The normal patched allele is expressed in medulloblastomas from mice with heterozygous germ-line mutation of patched

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Aquaporin water channels in liver: their significance in bile formation

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Silymarin retards collagen accumulation in early and advanced biliary fibrosis secondary to complete bile duct obliteration in rats

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Isolation and morphologic characterization of bile duct epithelial cells from normal rat liver.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Procollagen expression by nonparenchymal rat liver cells in experimental biliary fibrosis.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Characterization of fat-storing cell lines derived from normal and CCl4-cirrhotic livers. Differences in the production of interleukin-6

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

The hedgehog pathway regulates remodelling responses to biliary obstruction in rats.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Bile ductules and stromal cells express hedgehog ligands and/or hedgehog target genes in primary biliary cirrhosis.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

The gatekeeper effect of epithelial-mesenchymal transition regulates the frequency of breast cancer metastasis.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

The myofibroblastic conversion of peribiliary fibrogenic cells distinct from hepatic stellate cells is stimulated by platelet-derived growth factor during liver fibrogenesis.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

Hepatic stellate cell proliferation is an early platelet-derived growth factor-mediated cellular event in rat cholestatic liver injury

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

PDGF-mediated chemoattraction of hepatic stellate cells by bile duct segments in cholestatic liver injury

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2542850

4 September 2018

1 reference

12 December 2020

Transforming growth factor-beta and substrate stiffness regulate portal fibroblast activation in culture

1 reference

12 December 2020

Evidence for the epithelial to mesenchymal transition in biliary atresia fibrosis

1 reference

12 December 2020

Epithelial-mesenchymal transition contributes to portal tract fibrogenesis during human chronic liver disease

1 reference

12 December 2020

Keratin immunohistochemistry in normal human liver. Cytokeratin pattern of hepatocytes, bile ducts and acinar gradient

1 reference

12 December 2020

Proliferation and phenotypic modulation of portal fibroblasts in the early stages of cholestatic fibrosis in the rat

1 reference

12 December 2020

Secretion of MCP-1/CCL2 by bile duct epithelia induces myofibroblastic transdifferentiation of portal fibroblasts

1 reference

12 December 2020

Primary culture of cholangiocytes from normal mouse liver

1 reference

12 December 2020

Indian hedgehog is a major mediator of progesterone signaling in the mouse uterus

1 reference

12 December 2020

Biliary epithelial-mesenchymal transition in posttransplantation recurrence of primary biliary cirrhosis

1 reference

12 December 2020

Hedgehog-mediated mesenchymal–epithelial interactions modulate hepatic response to bile duct ligation

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI35875

1 reference

16 August 2017

1 reference

16 August 2017

1 reference