(Q36900791)

English

Hyperglycemic oxoaldehyde, glyoxal, causes barrier dysfunction, cytoskeletal alterations, and inhibition of angiogenesis in vascular endothelial cells: aminoguanidine protection.

scientific article published on 8 July 2009

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scholarly article

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2 February 2020

Hyperglycemic oxoaldehyde, glyoxal, causes barrier dysfunction, cytoskeletal alterations, and inhibition of angiogenesis in vascular endothelial cells: aminoguanidine protection (English)

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2 February 2020

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Sainath R Kotha

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2 February 2020

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Sashwati Roy

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2 February 2020

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Sean M Sliman

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2 February 2020

Timothy D Eubank

2

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2 February 2020

M Lakshmi Kuppusamy

4

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2 February 2020

Shariq I Sherwani

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2 February 2020

Elizabeth Susan O'Connor Butler

6

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2 February 2020

Periannan Kuppusamy

7

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2 February 2020

Clay B Marsh

9

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2 February 2020

David M Stern

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2 February 2020

Narasimham L Parinandi

11

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2 February 2020

publication date

8 July 2009

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2 February 2020

Molecular and Cellular Biochemistry

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2 February 2020

333

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2 February 2020

1-2

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2 February 2020

9-26

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2 February 2020

https://scigraph.springernature.com/pub.10.1007/s11010-009-0199-x

0 references

Protective effects of high-molecular weight polyethylene glycol (PEG) in human lung endothelial cell barrier regulation: role of actin cytoskeletal rearrangement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

The role of cytoskeleton in the regulation of vascular endothelial barrier function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Protein and nucleotide damage by glyoxal and methylglyoxal in physiological systems--role in ageing and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Advanced glycation endproducts in chronic heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Regulation of endothelial junctional permeability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Type 2 diabetes mellitus: prevention of macrovascular complications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Endothelial dysfunction in normal and abnormal glucose metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Endogenous secretory receptor for advanced glycation end-products and cardiovascular disease in end-stage renal disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Glutathione-S-transferase protects against oxidative injury of endothelial cell tight junctions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Advanced glycation end-products (AGEs) and heart failure: pathophysiology and clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Role of advanced glycation end products in hypertension and atherosclerosis: therapeutic implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Nitroaspirin (NCX-4016), an NO donor, is antiangiogenic through induction of loss of redox-dependent viability and cytoskeletal reorganization in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Endogenous alpha-oxoaldehydes and formation of protein and nucleotide advanced glycation endproducts in tissue damage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Methylglyoxal, oxidative stress, and hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Advanced glycation end products induce actin rearrangement and subsequent hyperpermeability of endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Protein modification in aging: an update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Advanced glycation endproducts (AGEs): Pharmacological inhibition in diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Advanced glycation end products: sparking the development of diabetic vascular injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Is methylglyoxal a causative factor for hypertension development?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Inhibitors of the Maillard reaction and AGE breakers as therapeutics for multiple diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Nuclear proteasome activation and degradation of carboxymethylated histones in human keratinocytes following glyoxal treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Advanced glycation endproducts--role in pathology of diabetic complications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Endogenous DNA damage in humans: a review of quantitative data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Regulation of tight junctions and loss of barrier function in pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Advanced glycation end-products and the progress of diabetic vascular complications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Role of methylglyoxal adducts in the development of vascular complications in diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Toxicity of glyoxals--role of oxidative stress, metabolic detoxification and thiamine deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Novel monoclonal antibody recognition of oxidative DNA damage adduct, deoxycytidine-glyoxal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Alteration of the intracellular pH and apoptosis induction in a retinal cell line by the AGE-inducing agent glyoxal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Mitochondrial dysfunction is an early indicator of doxorubicin-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Effect of glycation on basic fibroblast growth factor induced angiogenesis and activation of associated signal transduction pathways in vascular endothelial cells: possible relevance to wound healing in diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Pimagedine: a novel therapy for diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Protein glycation: creation of catalytic sites for free radical generation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Blood cells and vascular cell interactions in diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Aluminum toxicity is associated with mitochondrial dysfunction and the production of reactive oxygen species in plant cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Albumin-derived advanced glycation end-products trigger the disruption of the vascular endothelial cadherin complex in cultured human and murine endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Endothelial dysfunction and type 2 diabetes. Part 1: physiology and methods for exploring the endothelial function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Hyperglycemia and cardiovascular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Oxidant stress and endothelial cell dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Regulation of intercellular tight junctions by zonula occludens toxin and its eukaryotic analogue zonulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Induction of apoptosis by glyoxal in human embryonic lung epithelial cell line L132.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Hyperglycemia and cardiovascular disease in type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

BCL-2 expression or antioxidants prevent hyperglycemia-induced formation of intracellular advanced glycation endproducts in bovine endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Receptor-mediated endothelial cell dysfunction in diabetic vasculopathy. Soluble receptor for advanced glycation end products blocks hyperpermeability in diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Enhanced cellular oxidant stress by the interaction of advanced glycation end products with their receptors/binding proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Advanced glycation end products (AGEs) on the surface of diabetic erythrocytes bind to the vessel wall via a specific receptor inducing oxidant stress in the vasculature: a link between surface-associated AGEs and diabetic complications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Mechanism of autoxidative glycosylation: identification of glyoxal and arabinose as intermediates in the autoxidative modification of proteins by glucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

29 September 2017

Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

27 June 2018

Methylglyoxal: its presence and potential scavengers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

4 September 2018

Mercury activates vascular endothelial cell phospholipase D through thiols and oxidative stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

4 September 2018

Vitamin C-induced activation of phospholipase D in lung microvascular endothelial cells: regulation by MAP kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

4 September 2018

Dicarbonyl stress and apoptosis of vascular cells: prevention by alphaB-crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

4 September 2018

LPA and S1P increase corneal epithelial and endothelial cell transcellular resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

4 September 2018

Mechanism of advanced glycation end products-induced hyperpermeability in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

4 September 2018

Methylglyoxal administration induces diabetes-like microvascular changes and perturbs the healing process of cutaneous wounds.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

4 September 2018

The cytotoxic mechanism of glyoxal involves oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

4 September 2018

DNA damage by carbonyl stress in human skin cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

4 September 2018

Advanced glycation end products and endothelial dysfunction in type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

4 September 2018

Glyoxal and methylglyoxal trigger distinct signals for map family kinases and caspase activation in human endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3671881

4 September 2018

Enterocyte viability and mitochondrial function after graded intestinal ischemia and reperfusion in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19585224

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual roles of tight junction-associated protein, zonula occludens-1, in sphingosine 1-phosphate-mediated endothelial chemotaxis and barrier integrity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19585224

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of AGE precursor formation following unilateral ureteral obstruction in mouse kidneys by transgenic expression of alpha-dicarbonyl/L-xylulose reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19585224

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Protein glycation and endothelium dysfunction]

1 reference

https://pubmed.ncbi.nlm.nih.gov/19585224

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Demonstration of the cytotoxic effect of Advanced Glycation Endproducts (AGE-s)]

1 reference

https://pubmed.ncbi.nlm.nih.gov/19585224

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial dysfunction in diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19585224

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylglyoxal and advanced glycation endproducts: new therapeutic horizons?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19585224

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The early effects of elevated glucose on endothelial function as a target in the treatment of type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19585224

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reaction of metformin with dicarbonyl compounds. Possible implication in the inhibition of advanced glycation end product formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19585224

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The endothelial cell binding site for advanced glycation end products consists of a complex: an integral membrane protein and a lactoferrin-like polypeptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/19585224

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of protein modification by glyoxal and glycolaldehyde, reactive intermediates of the Maillard reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/19585224

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11010-009-0199-X

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19585224%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19585224%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19585224%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

ResearchGate publication ID

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