(Q36906352)

English

Transforming growth factor-beta suppresses the activation of CD8+ T-cells when naive but promotes their survival and function once antigen experienced: a two-faced impact on autoimmunity

scientific article published on 8 August 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Transforming growth factor-beta suppresses the activation of CD8+ T-cells when naive but promotes their survival and function once antigen experienced: a two-faced impact on autoimmunity (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Matthias G von Herrath

8

object named as

Matthias G von Herrath

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Richard Flavell

7

object named as

Richard A Flavell

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

author name string

Christophe M Filippi

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Amy E Juedes

2

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Janine E Oldham

3

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Ellie Ling

4

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Lisa Togher

5

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Yufeng Peng

6

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Europe PubMed Central

PMC publication ID

17 August 2017

language of work or name

0 references

publication date

8 August 2008

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Europe PubMed Central

PMC publication ID

17 August 2017

number of pages

9

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inferred from page(s)

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Europe PubMed Central

PMC publication ID

17 August 2017

57

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Europe PubMed Central

PMC publication ID

17 August 2017

10

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

2684-2692

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2551678/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

IL-6-dependent spontaneous proliferation is required for the induction of colitogenic IL-17-producing CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

29 September 2017

Innocuous IFNgamma induced by adjuvant-free antigen restores normoglycemia in NOD mice through inhibition of IL-17 production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

29 September 2017

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

29 September 2017

Tissue expression of PD-L1 mediates peripheral T cell tolerance.

1 reference

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29 September 2017

Restoring function in exhausted CD8 T cells during chronic viral infection

1 reference

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29 September 2017

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

29 September 2017

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

29 September 2017

Interleukin-17 family members and inflammation

1 reference

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29 September 2017

PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

29 September 2017

TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

29 September 2017

Tgf-beta inhibits activation and uveitogenicity of primary but not of fully polarized retinal antigen-specific memory-effector T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

29 September 2017

CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes

1 reference

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29 September 2017

The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

1 reference

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29 September 2017

CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

29 September 2017

CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

29 September 2017

Transforming growth factor-beta in T-cell biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

29 September 2017

Immune-mediated eradication of tumors through the blockade of transforming growth factor-beta signaling in T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

29 September 2017

Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

29 September 2017

Requirement for transforming growth factor beta1 in controlling T cell apoptosis

1 reference

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29 September 2017

Cyclin A2 transcriptional regulation: modulation of cell cycle control at the G1/S transition by peripheral cues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

29 September 2017

Transforming growth factor beta1 inhibits Fas ligand expression and subsequent activation-induced cell death in T cells via downregulation of c-Myc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

29 September 2017

Regulation of immune responses by TGF-beta

1 reference

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The dynamics of cyclin dependent kinase structure

1 reference

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29 September 2017

Control of CD4 effector fate: transforming growth factor beta 1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

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Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

29 September 2017

TGF-beta1 alters APC preference, polarizing islet antigen responses toward a Th2 phenotype

1 reference

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27 June 2018

Coordinate regulation of complex T cell populations responding to bacterial infection.

1 reference

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Coexpression of B7-1 and viral ("self") transgenes in pancreatic beta cells can break peripheral ignorance and lead to spontaneous autoimmune diabetes

1 reference

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Presentation of endogenous viral proteins in association with major histocompatibility complex class II: on the role of intracellular compartmentalization, invariant chain and the TAP transporter system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

27 June 2018

Fas- and activation-induced apoptosis are reduced in human T cells preactivated in the presence of TGF-beta 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

27 June 2018

Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

27 June 2018

Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

27 June 2018

Involvement of both T cell receptor V alpha and V beta variable region domains and alpha chain junctional region in viral antigen recognition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

27 June 2018

Cross-priming of diabetogenic T cells dissociated from CTL-induced shedding of beta cell autoantigens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

4 September 2018

TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

4 September 2018

TGF-β1 Regulates Lymphocyte Homeostasis by Preventing Activation and Subsequent Apoptosis of Peripheral Lymphocytes

1 reference

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4 September 2018

Expression of transgene encoded TGF-beta in islets prevents autoimmune diabetes in NOD mice by a local mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

4 September 2018

A role for TGF-beta in the generation and expansion of CD4+CD25+ regulatory T cells from human peripheral blood

1 reference

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4 September 2018

TGF-beta1 somatic gene therapy prevents autoimmune disease in nonobese diabetic mice

1 reference

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4 September 2018

Transforming growth factor-beta fails to inhibit allograft rejection or virus-induced autoimmune diabetes in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

4 September 2018

How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

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Genomic and biological variation among commonly used lymphocytic choriomeningitis virus strains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2551678

4 September 2018

Regulatory T-cells protect from type 1 diabetes after induction by coxsackievirus infection in the context of transforming growth factor-beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/18689691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/18689691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of TGF-beta1 on immune responses of naïve versus memory CD4+ Th1/Th2 T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18689691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential activation of CD8+ T cells by transforming growth factor-beta 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18689691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGF-beta 1 overexpression in murine pancreas induces chronic pancreatitis and, together with TNF-alpha, triggers insulin-dependent diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18689691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral administration of the immunodominant B-chain of insulin reduces diabetes in a co-transfer model of diabetes in the NOD mouse and is associated with a switch from Th1 to Th2 cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/18689691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct effects of TGF-beta 1 on CD4+ and CD8+ T cell survival, division, and IL-2 production: a role for T cell intrinsic Smad3

1 reference

https://pubmed.ncbi.nlm.nih.gov/18689691

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2337/DB08-0609

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

release_63p2n4ntzveyzckq4pqjfmngla

1 reference

https://api.fatcat.wiki/v0/release/63p2n4ntzveyzckq4pqjfmngla

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

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