(Q36908712)

English

A versatile bifunctional chelate for radiolabeling humanized anti-CEA antibody with In-111 and Cu-64 at either thiol or amino groups: PET imaging of CEA-positive tumors with whole antibodies

scientific article published on 8 November 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

A versatile bifunctional chelate for radiolabeling humanized anti-CEA antibody with In-111 and Cu-64 at either thiol or amino groups: PET imaging of CEA-positive tumors with whole antibodies (English)

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Andrew Raubitschek

9

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Andrew Raubitschek

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author name string

Lin Li

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

James Bading

2

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Europe PubMed Central

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17 August 2017

Paul J Yazaki

3

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Amitkumar H Ahuja

4

1 reference

Europe PubMed Central

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17 August 2017

Desiree Crow

5

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

David Colcher

6

1 reference

Europe PubMed Central

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17 August 2017

Lawrence E Williams

7

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Jeffrey Y C Wong

8

1 reference

Europe PubMed Central

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17 August 2017

Andrew Raubitschek

9

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Europe PubMed Central

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17 August 2017

John E Shively

10

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Europe PubMed Central

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17 August 2017

publication date

8 November 2007

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17 August 2017

Bioconjugate Chemistry

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17 August 2017

19

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Europe PubMed Central

PMC publication ID

17 August 2017

1

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

89-96

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Europe PubMed Central

PMC publication ID

17 August 2017

Improved biodistribution and radioimmunoimaging with poly(ethylene glycol)-DOTA-conjugated anti-CEA diabody

1 reference

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Tailoring antibodies for radionuclide delivery

1 reference

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Comparative uptakes and biodistributions of internalizing vs. noninternalizing copper-64 radioimmunoconjugates in cell and animal models of colon cancer

1 reference

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The promise of immuno-PET in radioimmunotherapy

1 reference

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Humanization of the anti-CEA T84.66 antibody based on crystal structure data

1 reference

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Tumor targeting of radiometal labeled anti-CEA recombinant T84.66 diabody and t84.66 minibody: comparison to radioiodinated fragments

1 reference

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In vivo transchelation of copper-64 from TETA-octreotide to superoxide dismutase in rat liver.

1 reference

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High-resolution microPET imaging of carcinoembryonic antigen-positive xenografts by using a copper-64-labeled engineered antibody fragment

1 reference

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Pathogenesis of IgA nephropathy.

1 reference

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Expression, purification, and characterization of a two domain carcinoembryonic antigen minigene (N-A3) in pichia pastoris. The essential role of the N-domain.

1 reference

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Newer approaches to the radiolabeling of monoclonal antibodies by use of metal chelates

1 reference

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29 September 2017

Selective reduction and proteolysis in the hinge region of liganded and unliganded antibodies. Identical kinetics suggest lack of major conformational change in the hinge region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2553277

29 September 2017

A facile, water-soluble method for modification of proteins with DOTA. Use of elevated temperature and optimized pH to achieve high specific activity and high chelate stability in radiolabeled immunoconjugates

1 reference

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27 June 2018

Performance of immuno-positron emission tomography with zirconium-89-labeled chimeric monoclonal antibody U36 in the detection of lymph node metastases in head and neck cancer patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2553277

4 September 2018

Optimization of labeling and metabolite analysis of copper-64-labeled azamacrocyclic chelators by radio-LC-MS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2553277

4 September 2018

Comparative in vivo stability of copper-64-labeled cross-bridged and conventional tetraazamacrocyclic complexes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2553277

4 September 2018

In vivo evaluation of pretargeted 64Cu for tumor imaging and therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2553277

4 September 2018

In vivo comparison of macrocyclic and acyclic ligands for radiolabeling of monoclonal antibodies with 177Lu for radioimmunotherapeutic applications

1 reference

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4 September 2018

Vinyl sulfone bifunctional derivatives of DOTA allow sulfhydryl- or amino-directed coupling to antibodies. Conjugates retain immunoreactivity and have similar biodistributions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2553277

4 September 2018

Numerical selection of optimal tumor imaging agents with application to engineered antibodies

1 reference

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4 September 2018

Maleimidocysteineamido-DOTA derivatives: new reagents for radiometal chelate conjugation to antibody sulfhydryl groups undergo pH-dependent cleavage reactions

1 reference

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4 September 2018

A comparative study of copper-67 radiolabeling and kinetic stabilities of antibody-macrocycle chelate conjugates.

1 reference

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4 September 2018

Labeling of immunoglobulins with bifunctional, sulfhydryl-selective, and photoreactive coumarins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17988078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo drug-linker stability of an anti-CD30 dipeptide-linked auristatin immunoconjugate

1 reference

https://pubmed.ncbi.nlm.nih.gov/17988078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new and convenient method for purification of 86Y using a Sr(II) selective resin and comparison of biodistribution of 86Y and 111In labeled Herceptin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17988078

12 December 2020

based on heuristic

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Identifiers

10.1021/BC700161P

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

release_k4pnbdx5q5eylpl4jj5ezyme3m

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24 November 2022

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

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