(Q36909378)

17 August 2017

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title

T-cell receptor gene therapy for cancer: the progress to date and future objectives (English)

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17 August 2017

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Sharyn Thomas

1

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17 August 2017

Daniel P Hart

2

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17 August 2017

Shao-An Xue

3

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17 August 2017

Michela Cesco-Gaspere

4

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17 August 2017

Hans J Stauss

5

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17 August 2017

language of work or name

English

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publication date

1 August 2007

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Expert Opinion on Biological Therapy

17 August 2017

published in

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17 August 2017

volume

7

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17 August 2017

issue

8

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17 August 2017

page(s)

1207-1218

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Cancer immunotherapy: insights from transgenic animal models

17 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Animal models of tumor immunity, immunotherapy and cancer vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Identification of a highly immunogenic HLA-A*01-binding T cell epitope of WT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Detection of Wilms' tumor antigen--specific CTL in tumor-draining lymph nodes of patients with early breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Melan-A/MART-1-specific CD4 T cells in melanoma patients: identification of new epitopes and ex vivo visualization of specific T cells by MHC class II tetramers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Genetic approaches for the induction of a CD4+ T cell response in cancer immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Tumor antigen-specific T helper cells in cancer immunity and immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Adoptive transfer of costimulated T cells induces lymphocytosis in patients with relapsed/refractory non-Hodgkin lymphoma following CD34+-selected hematopoietic cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Adoptive transfer of allogeneic antigen-specific T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

A phase I study of nonmyeloablative chemotherapy and adoptive transfer of autologous tumor antigen-specific T lymphocytes in patients with metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Human T lymphocytes transduced by lentiviral vectors in the absence of TCR activation maintain an intact immune competence

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

IL-21 sustains CD28 expression on IL-15-activated human naive CD8+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Transfer of specificity for human immunodeficiency virus type 1 into primary human T lymphocytes by introduction of T-cell receptor genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Functional reconstitution of class II MHC-restricted T cell immunity mediated by retroviral transfer of the alpha beta TCR complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

High efficiency TCR gene transfer into primary human lymphocytes affords avid recognition of melanoma tumor antigen glycoprotein 100 and does not alter the recognition of autologous melanoma antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Peptide fine specificity of anti-glycoprotein 100 CTL is preserved following transfer of engineered TCR alpha beta genes into primary human T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Reconstitution of CD8+ T cells by retroviral transfer of the TCR alpha beta-chain genes isolated from a clonally expanded P815-infiltrating lymphocyte.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Potentiation of tumor eradication by adoptive immunotherapy with T-cell receptor gene-transduced T-helper type 1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Reprogramming of virus-specific T cells into leukemia-reactive T cells using T cell receptor gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

A critical role of T cell antigen receptor-transduced MHC class I-restricted helper T cells in tumor protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Elimination of human leukemia cells in NOD/SCID mice by WT1-TCR gene-transduced human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Transfer of TCR genes into mature T cells is accompanied by the maintenance of parental T cell avidity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Adoptive transfer of allogeneic cytotoxic T lymphocytes equipped with a HLA-A2 restricted MART-1 T-cell receptor: a phase I trial in metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Cancer regression in patients after transfer of genetically engineered lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Development of WT1 peptide cancer vaccine against hematopoietic malignancies and solid cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Designer T cells by T cell receptor replacement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Efficiency of T-cell receptor expression in dual-specific T cells is controlled by the intrinsic qualities of the TCR chains within the TCR-CD3 complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Grafting primary human T lymphocytes with cancer-specific chimeric single chain and two chain TCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

The MHC reactivity of the T cell repertoire prior to positive and negative selection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Facilitating matched pairing and expression of TCR chains introduced into human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Enhanced antitumor activity of T cells engineered to express T-cell receptors with a second disulfide bond.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Gene therapy. Second child in French trial is found to have leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Gene therapy: therapeutic gene causing lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Gene therapy: is IL2RG oncogenic in T-cell development?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Gene therapy: X-SCID transgene leukaemogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Retroviral vector integration deregulates gene expression but has no consequence on the biology and function of transplanted T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

An inducible caspase 9 safety switch for T-cell therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Genetic modification of human T cells with CD20: a strategy to purify and lyse transduced cells with anti-CD20 antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Transcription start regions in the human genome are favored targets for MLV integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Retrovirus vectors: toward the plentivirus?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Codon bias and heterologous protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Codon modification of T cell receptors allows enhanced functional expression in transgenic human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Characterization of T cell receptors engineered for high affinity against toxic shock syndrome toxin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

High-affinity, peptide-specific T cell receptors can be generated by mutations in CDR1, CDR2 or CDR3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Class II-restricted T cell receptor engineered in vitro for higher affinity retains peptide specificity and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

TCRs with high affinity for foreign pMHC show self-reactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Generation of functional antigen-specific T cells in defined genetic backgrounds by retrovirus-mediated expression of TCR cDNAs in hematopoietic precursor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Long-term in vivo provision of antigen-specific T cell immunity by programming hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Rapid analysis of T-cell selection in vivo using T cell-receptor retrogenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Extrathymic generation of tumor-specific T cells from genetically engineered human hematopoietic stem cells via Notch signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Type and position of promoter elements in retroviral vectors have substantial effects on the expression level of an enhanced green fluorescent protein reporter gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

CD4 T cells in tumor immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Simultaneous generation of CD8+ and CD4+ melanoma-reactive T cells by retroviral-mediated transfer of a single T-cell receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Primary human lymphocytes transduced with NY-ESO-1 antigen-specific TCR genes recognize and kill diverse human tumor cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Generation of tumor-specific, HLA class I-restricted human Th1 and Tc1 cells by cell engineering with tumor peptide-specific T-cell receptor genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Generation of T cell help through a MHC class I-restricted TCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

Redirecting human CD4+ T lymphocytes to the MHC class I-restricted melanoma antigen MAGE-A1 by TCR alphabeta gene transfer requires CD8alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

CD8 alpha coreceptor to improve TCR gene transfer to treat melanoma: down-regulation of tumor-specific production of IL-4, IL-5, and IL-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.8.1207

10.1517/14712598.7.8.1207

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference