(Q36911407)

English

Toxoplasma gondii rhoptry 16 kinase promotes host resistance to oral infection and intestinal inflammation only in the context of the dense granule protein GRA15.

scientific article published on April 2013

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23545295%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Toxoplasma gondii rhoptry 16 kinase promotes host resistance to oral infection and intestinal inflammation only in the context of the dense granule protein GRA15 (English)

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27 February 2020

Toxoplasma gondii

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host resistance

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based on heuristic

inferred from title

4

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27 February 2020

9

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27 February 2020

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object named as

Lindsay Julien

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27 February 2020

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Kirk D C Jensen

1

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27 February 2020

Kenneth Hu

2

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27 February 2020

Ryan J Whitmarsh

3

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27 February 2020

Diana Lu

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27 February 2020

Lieping Chen

7

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27 February 2020

Christopher A Hunter

8

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27 February 2020

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1 April 2013

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27 February 2020

Infection and Immunity

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27 February 2020

81

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27 February 2020

6

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27 February 2020

2156-2167

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27 February 2020

Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells

1 reference

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29 September 2017

Integrated bioinformatic and targeted deletion analyses of the SRS gene superfamily identify SRS29C as a negative regulator of Toxoplasma virulence

1 reference

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29 September 2017

The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology

1 reference

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29 September 2017

The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response.

1 reference

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29 September 2017

Targeted disruption of Toxoplasma gondii serine protease inhibitor 1 increases bradyzoite cyst formation in vitro and parasite tissue burden in mice

1 reference

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29 September 2017

Insights into inflammatory bowel disease using Toxoplasma gondii as an infectious trigger

1 reference

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29 September 2017

Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it

1 reference

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29 September 2017

Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676013

29 September 2017

A critical role for SOCS3 in innate resistance to Toxoplasma gondii

1 reference

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29 September 2017

Toxoplasma gondii effectors are master regulators of the inflammatory response

1 reference

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29 September 2017

Toxoplasma polymorphic effectors determine macrophage polarization and intestinal inflammation.

1 reference

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29 September 2017

Control of Toxoplasma reactivation by rescue of dysfunctional CD8+ T-cell response via PD-1-PDL-1 blockade

1 reference

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29 September 2017

Strain-specific activation of the NF-kappaB pathway by GRA15, a novel Toxoplasma gondii dense granule protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676013

29 September 2017

Toxoplasma rhoptry protein 16 (ROP16) subverts host function by direct tyrosine phosphorylation of STAT6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676013

29 September 2017

Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676013

29 September 2017

A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676013

29 September 2017

Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection

1 reference

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29 September 2017

Small intestinal inflammation following oral infection with Toxoplasma gondii does not occur exclusively in C57BL/6 mice: review of 70 reports from the literature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676013

29 September 2017

Virulent Toxoplasma gondii evade immunity-related GTPase-mediated parasite vacuole disruption within primed macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676013

29 September 2017

Alternative activation of macrophages: an immunologic functional perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676013

29 September 2017

Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

1 reference

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29 September 2017

Two ways to survive infection: what resistance and tolerance can teach us about treating infectious diseases

1 reference

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29 September 2017

Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine

1 reference

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29 September 2017

Gr1(+) inflammatory monocytes are required for mucosal resistance to the pathogen Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3676013

29 September 2017

PD-1 and its ligands in tolerance and immunity

1 reference

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29 September 2017

Bradyzoite-specific surface antigen SRS9 plays a role in maintaining Toxoplasma gondii persistence in the brain and in host control of parasite replication in the intestine

1 reference

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29 September 2017

Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue

1 reference

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29 September 2017

Polymorphic secreted kinases are key virulence factors in toxoplasmosis

1 reference

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29 September 2017

Prevalence of latent and reactivated Toxoplasma gondii parasites in HIV-patients from Uganda

1 reference

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29 September 2017

The host cell transcription factor hypoxia-inducible factor 1 is required for Toxoplasma gondii growth and survival at physiological oxygen levels

1 reference

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29 September 2017

Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases.

1 reference

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29 September 2017

New lessons from old pathogens: what parasitic infections have taught us about the role of nuclear factor-kappaB in the regulation of immunity

1 reference

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1 reference

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29 September 2017

Association of CD4+ T cell-dependent, interferon-gamma-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii

1 reference

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29 September 2017

GM-CSF: a role in immune and inflammatory reactions in the intestine

1 reference

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1 reference

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Effect of the strain of Toxoplasma gondii on the development of toxoplasmic encephalitis in mice treated with antibody to interferon-gamma

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Genetic regulation of early survival and cyst number after peroral Toxoplasma gondii infection of A x B/B x A recombinant inbred and B10 congenic mice

1 reference

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27 June 2018

Immune responses associated with early survival after peroral infection with Toxoplasma gondii.

1 reference

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Interleukin-15-dependent NKp46+ innate lymphoid cells control intestinal inflammation by recruiting inflammatory monocytes.

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IL-10-independent STAT3 activation by Toxoplasma gondii mediates suppression of IL-12 and TNF-alpha in host macrophages.

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TNF-alpha, nitric oxide and IFN-gamma are all critical for development of necrosis in the small intestine and early mortality in genetically susceptible mice infected perorally with Toxoplasma gondii

1 reference

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4 September 2018

IL-10 is required for prevention of necrosis in the small intestine and mortality in both genetically resistant BALB/c and susceptible C57BL/6 mice following peroral infection with Toxoplasma gondii

1 reference

https://pubmed.ncbi.nlm.nih.gov/23545295

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii. Role for synthesis of inorganic nitrogen oxides from L-arginine

1 reference

https://pubmed.ncbi.nlm.nih.gov/23545295

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early kinetics of Toxoplasma gondii infection in mice infected orally with cysts of an avirulent strain

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternatively activated macrophages inhibit T-cell proliferation by Stat6-dependent expression of PD-L2

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

A Cluster of Interferon-γ-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/IAI.01185-12

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23545295%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23545295%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23545295%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

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